Lung protection strategy for patients with inadequate oxygenation (eg, PARDS) |
- PIP: Adjust for target tidal volume 4 to 6 mL/kg (maximum 10 mL/kg); higher PIP (up to 30 to 40 cm H2O) required for poor lung compliance
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- PEEP: Increase for hypoxemia, atelectasis, may be >10 cm H2O
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- SpO2: Target 88 to 92%/55 to 88 mmHg
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- PaO2: Target 88 to 92%/55 to 88 mmHg
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Obstructive airway disease causing inadequate ventilation (eg, status asthmaticus or bronchiolitis) |
- RR: Near or below physiologic to prevent breath-stacking and dynamic hyperinflation
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- IT: Low/normal, goal I:E of 1:3 to 1:5 or greater
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- PIP: >Plateau pressure and <40 cm H2O
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- PaCO2: Permissive hypercapnia, goal pH >7.20
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Airway protection |
- Minimize settings to maintain adequate oxygenation and ventilation and avoid ventilator-associated lung injury
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