Overview of the diagnostic evaluation for neonatal acute kidney injury (AKI)*

SCr: serum creatinine.
* This algorithm reflects the diagnostic evaluation of the author for the UpToDate topic on the evaluation, management, and prognosis of neonatal acute kidney injury.
¶ Details of the underlying etiologies can be found in the UpToDate topic on etiology of neonatal AKI.
Δ Refer to UpToDate topics on renal cystic disease and renal hypodysplasia.
◊ The fluid challenge consists of the intravenous administration of 10 to 20 mL/kg of isotonic saline given over one to two hours.