Effect of HOIL-1 and HOIP mutations in fibroblasts and monocytes

HOIL-1: heme-oxidized IRP2 ubiquitin ligase-1; HOIP: HOIL-1 interacting protein; IL-1R: interleukin-1 receptor; MyD88: myeloid differentiation primary response protein 88; IRAK: interleukin-1 receptor-associated kinase; NEMO: nuclear factor (NF)-kappa-B essential modulator; IKK: inhibitor of nuclear factor (NF)-kappa-B kinase; NF-kappa-B: nuclear factor (NF) for the kappa light chain enhancer in B cells.