Emergencies associated with pancytopenia

Neutropenia (new diagnosis or associated with fever/infection)
Symptomatic anemia (eg, cardiac ischemia, hemodynamic instability, worsening congestive heart failure)
Thrombocytopenia (platelets <10,000/microL, or <50,000/microL associated with bleeding)
Disseminated intravascular coagulation
Abnormal peripheral blood smear (eg, microangiopathy, blasts)
Severe aplastic anemia
Hemophagocytic lymphohistiocytosis
Metabolic emergencies (eg, symptomatic hypercalcemia, hyperkalemia, tumor lysis syndrome)

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