Topical analgesic | Usual dose (adult) |
Topical nonsteroidal antiinflammatory drugs (NSAIDs)* | |
Diclofenac topical gel (1%) | Knees: rub in 4 g of gel to affected knee(s) three to four times daily Hands: rub in 2 g of gel to affected joint(s) three to four times daily Maximum 16 g per joint per day; 32 g total per day |
Diclofenac topical solution drops (1.5%) | Knees: rub in 40 drops to affected knee(s) up to four times daily |
Diclofenac topical solution pump (2%) | Knees: rub in two pump actions to affected knee(s) up to two times daily |
Ibuprofen topical gel (5, 10%); not available in the United States | Knees or hands: rub in dose (depends on joint size and location) up to four times daily; refer to product-specific information for detail |
Ketoprofen topical gel (2.5%); not available in the United States | Knees or hands: rub in 2 to 4 g of gel two to four times daily (maximum 15 g of gel per day); refer to product-specific information for detail |
Topical capsaicin¶ | |
Capsaicin creams, gels, liquids, lotions (0.025 to 0.1%) | Rub in a small amount (pea-sized) one to four times daily; the preparation most often studied in osteoarthritis was 0.025% cream |
Capsaicin topical patches (0.025 to 0.05%) | Apply one patch to affected area for up to eight hours (maximum four patches per day) |
Combination therapies | |
Diclofenac-lidocaine gel (diclofenac 1% and lidocaine 4.5%) | Rub in to affected joint(s) up to four times daily |
Diclofenac-lidocaine patch (diclofenac 1.25% and lidocaine 4.5%) | Apply one patch to affected area for up to 12 hours (maximum two patches per day) |
* For patients already on oral NSAIDs, topical therapies are generally not recommended because they are unlikely to provide additional pain relief. Gel measurements from tubes are approximate.
¶ Pain relief usually begins within the first week of treatment, and full effect is seen with regular application over approximately four weeks. Topical capsaicin should not come in contact with mucous membranes, abraded skin, eyes, or genital areas.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟