Common clinical manifestations of gluten-related disorders

	Celiac disease	Non-celiac gluten sensitivity	Wheat allergy
Time from exposure to symptoms	Hours to months	Hours to days	Minutes to hours
Gastrointestinal
Diarrhea	X	X	X
Abdominal pain	X	X	X
Constipation	X	X	X
Gas/bloat/distention	X	X	X
Poor weight gain	X	X	X
Malodorous, fatty stools	X
Vomiting	X	X	X
Extraintestinal
Pubertal delay	X
Unexplained weight loss	X	X	X
Poor height gain	X
Bone/joint pain	X	X	X
Rash of dermatitis herpetiformis	X
Eczema		X	X
Hives/atopic dermatitis			X
Fatigue	X	X	X
Headache/migraine	X	X	X
Foggy mind	X	X
Angioedema			X
Anaphylaxis			X
Respiratory
Asthma			X
Cough			X
Postnasal drip, throat clearing, rhinitis			X

From: Hill ID, Fasano A, Guandalini S, et al. NASPGHAN clinical report on the diagnosis and treatment of gluten-related disorders. J Pediatr Gastroenterol Nutr 2016; 63(1):156-65. DOI: 10.1097/MPG.0000000000001216. Copyright © 2016 ESPGHAN and NASPGHAN. Reproduced with permission from Lippincott Williams & Wilkins. Unauthorized reproduction of this material is prohibited.

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Common clinical manifestations of gluten-related disorders