Prothrombin G20210A mutation

The prothrombin G20210A mutation is a single G-to-A point mutation at position 20210 in the 3' untranslated region of the prothrombin (factor II) gene. The mutation does not affect the protein-coding region (exons) of the gene. Refer to the UpToDate topics on the prothrombin G20210A mutation and management of patients with inherited thrombophilias for further information.