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Upper limit of normal (80th centile) values for serum streptococcal antibody titers in children in the United States[1]

Upper limit of normal (80th centile) values for serum streptococcal antibody titers in children in the United States[1]
Age (years) Upper limit of normal (international units/mL)
ASO titer ADB titer
2 160 240
3 120 60
4   240
5 160 320
6 240 480
7   640
8    
9    
10 320  
11   800
12   480
ASO: anti-streptolysin O; ADB: anti-deoxyribonuclease B.
Reference:
  1. Kaplan EL, Rothermel CD, Johnson DR. Antistreptolysin O and anti-deoxyribonuclease B titers: Normal values for children ages 2 to 12 in the United States. Pediatrics 1998; 101:86.
Reprinted by permission from: European Journal of Clinical Microbiology & Infectious Diseases. Parks T, Smeesters PR, Curtis N, Steer AC. ASO titer or not? When to use streptococcal serology: A guide for clinicians. Eur J Clin Microbiol Infect Dis 2015; 34:845. Copyright © 2015. https://link.springer.com/journal/10096.
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