Version May 2024
| Tumor type | CNS WHO grade | Characteristic molecular genetic alterations |
| Ganglioglioma | 1 | BRAF |
| Gangliocytoma | 1 | BRAF |
| Desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma | 1 | |
| Dysembryoplastic neuroepithelial tumor | 1 | FGFR1 |
| Diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters* | NA | Methylome |
| Papillary glioneuronal tumor | 1 | PRKCA |
| Rosette-forming glioneuronal tumor | 1 | FGFR1, PIK3CA, NF1 |
| Myxoid glioneuronal tumor | 1 | PDGFRA |
| Diffuse leptomeningeal glioneuronal tumor | NA | KIAA1549-BRAF, 1p, methylome |
| Multinodular and vacuolating neuronal tumor | 1 | MAPK pathway genes |
| Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) | 1 | PTEN |
| Central neurocytoma | 2 | |
| Extraventricular neurocytoma | 2 | FGFR genes (FGFR1-TACC1), IDH-wildtype |
| Cerebellar liponeurocytoma | 2 |
WHO: World Health Organization; CNS: central nervous system; FGFR: fibroblast growth factor receptor; NA: not assigned; PRKCA: protein kinase C alpha; PIK3CA: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; NF1: neurofibromin 1; PDGFRA: platelet-derived growth factor receptor alpha; MAPK: mitogen-activated protein kinase; PTEN: phosphatase and tensin homolog; IDH: isocitrate dehydrogenase.
* Provisional tumor.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
