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Lymph node groups: Location, lymphatic drainage and selected differential diagnosis*

Lymph node groups: Location, lymphatic drainage and selected differential diagnosis*
Location Lymphatic drainage Causes
Submandibular Tongue, submaxillary gland, lips and mouth, conjunctivae Infections of head, neck, sinuses, ears, eyes, scalp, pharynx
Submental Lower lip, floor of mouth, tip of tongue, skin of cheek Mononucleosis syndromes, Epstein-Barr virus, cytomegalovirus, toxoplasmosiss
Jugular Tongue, tonsil, pinna, parotid Pharyngitis organisms, rubella
Posterior cervical Scalp and neck, skin of arms and pectorals, thorax, cervical and axillary nodes Mononucleosis syndromes, Epstein-Barr virus, tuberculosis, lymphoma, head and neck malignancy
Suboccipital Scalp and head Local infection
Postauricular External auditory meatus, pinna, scalp Local infection
Preauricular Eyelids and conjunctivae, temporal region, portions of the auricle and external ear canal Local infection
Right supraclavicular node Mediastinum, lungs, esophagus Lung, retroperitoneal, or esophageal cancer; lymphoma; bacterial or fungal infection
Left supraclavicular node Thorax, abdomen (via thoracic duct) Gastrointestinal, abdominal, thoracic, or retroperitoneal cancer; lymphoma; bacterial or fungal infection
Axillary Arm, thoracic wall, breast Infections, cat-scratch disease, lymphoma, breast cancer, silicone implants, brucellosis, melanoma
Epitrochlear Ulnar aspect of forearm and hand Infections, lymphoma, sarcoidosis, tularemia, secondary syphilis
Inguinal Penis, scrotum, vulva, vagina, perineum, gluteal region, lower abdominal wall, lower anal canal Infections of the leg or foot, STIs (eg, herpes simplex virus, gonococcal infection, syphilis, chancroid, granuloma inguinale, lymphogranuloma venereum), lymphoma, pelvic malignancy, bubonic plague

STIs: sexually transmitted infections.

* This is a partial list and not meant to be all-inclusive.

Adapted with permission from: Ferrer R. Lymphadenopathy: differential diagnosis and evaluation. Am Fam Physician 1998; 58:1313. Copyright © 1998 American Academy of Family Physicians. All rights reserved.

Updated with corrections in February, 2021.
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