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Centers for disease control definitions for mediastinitis

Centers for disease control definitions for mediastinitis
Mediastinitis must meet at least one of the following criteria:
  1. Patient has organisms identified from mediastinal tissue or fluid by a culture or nonculture based microbiologic testing method which is performed for purposes of clinical diagnosis or treatment (eg, not active surveillance culture/testing).
  1. Patient has evidence of mediastinitis on gross anatomic or histopathologic exam.
  1. Patient has at least one of the following signs or symptoms:
    • Fever (>38.0°C),
    • Chest pain*, or
    • Sternal instability*
    And at least one of the following:
    1. Purulent drainage from mediastinal area
    2. Mediastinal widening on imaging test
  1. Patient ≤1 year of age has at least one of the following signs or symptoms:
    • Fever (>38.0°C),
    • Hypothermia (<36.0°C),
    • Apnea*,
    • Bradycardia*, or
    • Sternal instability*
    And at least one of the following:
    1. Purulent drainage from mediastinal area
    2. Mediastinal widening on imaging test
Reporting instruction:
  • Mediastinal space is the area under the sternum and in front of the vertebral column, containing the heart and its large vessels, trachea, esophagus, thymus, lymph nodes, and other structures and tissues. It is divided into anterior, middle, posterior, and superior regions.
  • Report mediastinitis (MED) following cardiac surgery that is accompanied by osteomyelitis as SSI-MED, rather than SSI-BONE.
SSI: surgical site infection.
* With no other recognized cause.
Modified from: CDC/NHSN Surveillance Definitions for Specific Types of Infections, January 2016. Available at: http://www.cdc.gov/nhsn/PDFs/pscManual/17pscNosInfDef_current.pdf (Accessed on June 10, 2016).
Graphic 108802 Version 1.0

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