| Patients with history of TB (current or past) |
- Persistent or progressive clinical and/or radiographic findings while on antituberculous therapy
|
- Lack of conversion of cultures to negative during first three months of antituberculous therapy
|
- Incomplete adherence to prescribed antituberculous therapy
|
- Lack of directly observed therapy or poorly supervised antituberculous therapy
|
- Documented treatment failure or relapse
|
- History of an inappropriate treatment regimen, including too few effective drugs or inadequate drug dosing
|
| Patients without prior history of TB |
- Exposure to an individual with known or suspected drug-resistant TB
|
- Residence in or travel to a region with high prevalence of drug-resistant TB
|
- Residence in or work in an institution or setting with documented drug-resistant TB
|
- Among foreign-born individuals: Emigration within the previous two years from a region with known drug-resistant TB
|
