Version May 2024
| Bethesda class | Diagnostic category | Risk of malignancy* or NIFTP Range (mean) | Risk of malignancy* excluding NIFTP Mean |
| I | Nondiagnostic | 5 to 20%¶ (13%) | 12% |
| II | Benign | 2 to 7% (4%) | 2% |
| III | Atypia of undetermined significance | 13 to 30%, highest with nuclear atypia (22%) | 16% |
| IV | Follicular neoplasm | 23 to 34% (30%) | 23% |
| Follicular neoplasm-oncocytic follicular neoplasmΔ | 25 to 50% (N/A) | N/A | |
| V | Suspicious for malignancy | 67 to 83% (74%) | 65% |
| VI | Malignant | 97 to 100% (97%) | 94% |
N/A: not available; NIFTP: noninvasive follicular thyroid neoplasm with papillary-like nuclear features.
* Cancer risk estimates are skewed by selection bias because many thyroid nodules (especially those diagnosed as benign or atypia of undetermined significance) might not undergo surgical excision.
¶ Risk of malignancy is higher in nondiagnostic solid lesions than those that are >50% cystic.
Δ Previously called Hürthle cell neoplasm.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
