Version May 2024
| Living in geographic regions with rates of penicillin-nonsusceptible S. pneumonia exceeding 10%* |
| Age ≥65 years |
| Hospitalization in the last 5 days |
| Antibiotic use in the previous month |
| Immunocompromise |
| Multiple comorbidities (eg, diabetes or chronic cardiac, hepatic, or renal disease) |
| Severe infection (eg, evidence of systemic toxicity with temperature of ≥102°F, threat of suppurative complications) |
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