Diseases associated with familial pleuropulmonary blastoma
Diseases associated with familial pleuropulmonary blastoma
Lungs
Pleuropulmonary blastoma
Lung cysts
Urinary tract
Cystic nephroma
Kidney cysts
Wilms tumor
Bladder cancer (rhabdomyosarcoma, transition-cell carcinoma, papilloma)
Intestine
Polyps
Thyroid
Nodular hyperplasias
Follicular and papillary carcinomas
Blood
Leukemia/lymphoma
Gonadal tumors
Stromal sex cord tumors (Sertoli-Leydig)
Germ cell tumors (seminoma, dysgerminoma)
Brain tumors
Medulloblastoma
Glioblastoma multiforme
Ependymoma
Sarcoma
Other
Nasal chondromesenchymal hamartoma
Hepatic cystic mesenchymal hamartoma
Synovial sarcoma
Globe melanosarcoma or medulloepithelioma
Neuroblastoma
Anaplastic carcinoma of the pharynx
Neurofibromatosis type 1
These diseases were associated with pleuropulmonary blastoma in the index case or family members, as reported from the International Pleuropulmonary Blastoma Registry.
Data from: Priest JR, Williams GM, Hill DA, et al. Pulmonary cysts in early childhood and the risk of malignancy. Pediatr Pulmonol 2009; 44:14.
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