Brain MRI: A two-year-old Malawian boy with cerebral malaria and retinopathy

(A) Axial T2 view: Diffuse brain swelling with complete loss of sulcal markings. The T2 signal in gray and white matter is diffuse, and the ventricles are effaced.
(B) Sagittal T1 FLAIR: Diffuse brain swelling with effacement of basilar cisterns and fourth ventricle, brainstem compression, and tonsillar herniation below the foramen magnum. There is complete loss of sulcal markings in cerebrum and cerebellum and downward herniation of the diaphragmatic sella.