Calculator: Splenic Marginal Zone Lymphoma Study Group (SMZLSG) prognostic index in adults

Input

Hemoglobin
Platelets
LDH score	LDH normal (0)
	LDH high (1)
LAD score	Extrahilar adenopathy absent (0)
	Extrahilar adenopathy present (1)

Result

Important: Inputs must be complete to perform calculation.


Prognostic index		index

Decimal precision

Interpretation

SMZLSG prognostic index	Risk category	5-year survival* Derivation cohort	5-year survival* Validation cohort
≥2.6	Low risk	94%	96%
≥0.9 and <2.6	Intermediate risk	78%	88%
<0.9	High risk	69%	44%

Notes

*Lymphoma-specific survival at 5 years.
LDH: lactate dehydrogenase; LAD: lymphadenopathy.

Equations used

Prognostic_index = (0.2 * Hemoglobin) + (0.006 * Platelets) - LDH_score - LAD_score

Equation parameters, such as LDH score, have 2 or more discrete values that may be used in the calculation. The numbers in the parentheses, eg, (0), represent the values that will be used.

References

Montalban C, Abraira V, Arcaini L, et el. Splenic Marginal Zone Lymphoma Study Group. Risk stratification for Splenic Marginal Zone Lymphoma based on haemoglobin concentration, platelet count, high lactate dehydrogenase level and extrahilar lymphadenopathy: development and validation on 593 cases. Br J Haematol 2012; 159:164.

Only digits 0 to 9 and a single decimal point (".") are acceptable as numeric inputs. Attempted input of other characters into a numeric field may lead to an incorrect result.

Information on this page may not appear correctly if printed.

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Calculator: Splenic Marginal Zone Lymphoma Study Group (SMZLSG) prognostic index in adults