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Phenome-wide association study and precision medicine of cardiovascular diseases in the post-COVID-19 era
Qian Cao, Xin Du, Xiao-yan Jiang, Yuan Tian, Chen-hao Gao, Zi-yu Liu, Ting Xu, Xing-xing Tao, Ming Lei, Xiao-qiang Wang, Lingyu Linda Ye & Dayue Darrel DuanÂ
doi : 10.1038/s41401-023-01119-1
Volume 44 Issue 12, December 2023
Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics
Mei Jin, Jian Fang, Jiao-jiao Wang, Xin Shao, Suo-wen Xu, Pei-qing Liu, Wen-cai Ye & Zhi-ping LiuÂ
Chemogenetic inhibition of subicular seizure-activated neurons alleviates cognitive deficit in male mouse epilepsy model
Lin Yang, Qi Zhang, Xue-qing Wu, Xiao-yun Qiu, Fan Fei, Nan-xi Lai, Yu-yi Zheng, Meng-di Zhang, Qing-yang Zhang, Yu Wang, Fei Wang, Ceng-lin Xu, Ye-ping Ruan, Yi Wang & Zhong ChenÂ
Vincamine as an agonist of G-protein-coupled receptor 40 effectively ameliorates diabetic peripheral neuropathy in mice
Jia-wen Xu, Xu Xu, Yun Ling, Yan-chun Wang, Yu-jie Huang, Juan-zhen Yang, Jia-ying Wang & Xu ShenÂ
Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog
Mei-jie Dai, Xing-xing Gui, Shu-miao Jia, Shu-ting Lv, Hao Dou & Wei CuiÂ
PACAP/PAC1-R activation contributes to hyperalgesia in 6-OHDA-induced Parkinson’s disease model rats via promoting excitatory synaptic transmission of spinal dorsal horn neurons
Li-guo Dong, Meng-qi An, Han-ying Gu, Li-ge Zhang, Jin-bao Zhang, Cheng-jie Li, Cheng-jie Mao, Fen Wang & Chun-feng LiuÂ
Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling
Hui-yun Ye, Ya-li Song, Wen-ting Ye, Chong-xiang Xiong, Jie-mei Li, Jin-hua Miao, Wei-wei Shen, Xiao-long Li & Li-li ZhouÂ
Decreased syntaxin17 expression contributes to the pathogenesis of acute pancreatitis in murine models by impairing autophagic degradation
Tian-tian Wang, Li-chun Zhang, Zhen Qin, Shu-jun Chen, Jing-min Zeng, Jing-yan Li, Lin An, Cai-yan Wang, Yong Gao, Li-ming Wang, Zhong-xiang Zhao, Zhong-qiu Liu & Shao-gui WangÂ
Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy
Jia-ling Ji, Hui-min Shi, Zuo-lin Li, Ran Jin, Gao-ting Qu, Hui Zheng, E. Wang, Yun-yang Qiao, Xing-yue Li, Ling Ding, Da-fa Ding, Liu-cheng Ding, Wei-hua Gan, Bin Wang & Ai-qing ZhangÂ
Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium
Jie Wang, Mei Bai, Cui Zhang, Ning An, Li Wan, Xiao-ning Wang, Rong-hui Du, Yan Shen, Zhi-yao Yuan, Xu-dong Wu, Xue-feng Wu & Qiang XuÂ
LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles
Xiao-jiao-yang Li, Fei Zhou, Ya-jing Li, Xiao-yong Xue, Jiao-rong Qu, Gui-fang Fan, Jia Liu, Rong Sun, Jian-zhi Wu, Qi Zheng & Run-ping LiuÂ
Downregulated calmodulin expression contributes to endothelial cell impairment in diabetes
Tian-tian Liu, Huan-huan Xu, Ze-juan Liu, He-ping Zhang, Hai-tao Zhou, Zhi-xiang Zhu, Zhi-qiang Wang, Jing-yi Xue, Qiang Li, Yi Ma, Hong-jie You & Da-li LuoÂ
Sinomenine ameliorates collagen-induced arthritis in mice by targeting GBP5 and regulating the P2X7 receptor to suppress NLRP3-related signaling pathways
Juan-min Li, Hai-shan Deng, Yun-da Yao, Wei-ting Wang, Jia-qin Hu, Yan Dong, Pei-xun Wang, Liang Liu, Zhong-qiu Liu, Ying Xie, Lin-lin Lu & Hua ZhouÂ
Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer
Shuai Wang, Yu-fei Wang, Guang Yang, Hui-hui Zhang, Hong-feng Yuan, Chun-yu Hou, Li-na Zhao, Yu-hong Suo, Jiao Sun, Lin-lin Sun, Pan Lv, Yan Sun, Ning-ning Zhang, Xiao-dong Zhang & Wei LuÂ
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells
Wa Ding, Jin-xiang Wang, Jun-zheng Wu, Ao-chu Liu, Li-ling Jiang, Hai-chuan Zhang, Yi Meng, Bing-yuan Liu, Guan-jie Peng, En-zhe Lou, Qiong Mao, Huan Zhou, Dao-lin Tang, Xin Chen, Jin-bao Liu & Xian-ping ShiÂ
Author Correction: Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans
Yuan-dong Zheng, Hua Zhang, Yan Zhan, Yi-cong Bian, Sheng Ma, Hai-xian Gan, Xiao-juan Lai, Yong-qiang Liu, Yan-chun Gong, Xue-fang Liu, Hong-bin Sun, Yong-guo Li, Da-fang Zhong, Li-yan Miao & Xing-xing DiaoÂ
Author Correction: Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition
Kai-long Jiang, Chang-mei Liu, Li-tong Nie, Hai-ni Jiang, Lei Xu, Kun-zhi Zhang, Li-xia Fan, An-hui Gao, Lu-lin Lin, Xiang-yu Wang, Min-jia Tan, Qi-qing Zhang, Yu-bo Zhou & Jia LiÂ
