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Comparing the relative efficacy of therapeutics for eosinophilic oesophagitis: is counting eosinophils the right target?
Ikuo Hirano1, David Katzka2
doi : 10.1136/gutjnl-2023-330705
November 2023 - Volume 72 - 11
Defective microbial sensing and clearance in perianal Crohn’s disease: a role for complement factor B
Arya Ghate,1 Holm H. Uhlig
Quest for immunological biomarkers in the management of CHB patients
Antonio Bertoletti , Nina Le Bert
Accuracy of measuring colorectal polyp size in pathology: a prospective study
Roupen Djinbachian ,1,2 Abdelhakim Khellaf,3 Brandon Noyon,2 Geneviève Soucy,3 Bich N Nguyen,3 Daniel von Renteln
Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis
Pierfrancesco Visaggi ,1 Brigida Barberio, 2 Giulio Del Corso,3 Nicola de Bortoli ,1 Christopher J Black ,4 Alexander C Ford ,5 Edoardo Savarino
Bismuth quadruple three-in-one single capsule three times a day increases effectiveness compared with the usual four times a day schedule: results from the European Registry on Helicobacter pylori Management (Hp-EuReg)
?ngeles Pérez-Aisa, Olga P Nyssen, Alma Keco-Huerga, Lu?s Rodrigo, Alfredo J Lucendo , Blas J Gomez-Rodriguez, Juan Ortu?o, M?nica Perona, José Mar?a Huguet, Oscar N??ez, Luis Fernandez-Salazar, Jesus Barrio, Angel Lanas, Eduardo Iyo, Pilar Mata Romero, Miguel Fern?ndez-Bermejo, Barbara Gomez, Ana Garre, Judith Gomez-Camarero, Luis Javier Lamuela, Ana Campillo, Luisa de la Pe?a-Negro, Manuel Dominguez Cajal, Luis Bujanda, Diego Burgos-Santamar?a , Fernando Bermejo, V?ctor Gonz?lez-Carrera, Ram?n Pajares, Pedro Almela Notari, Javier Tejedor-Tejada, Montserrat Planella, Itxaso Jiménez, Yolanda Arguedas L?zaro, Antonio Cuadrado-Lav?n, Isabel Pérez-Mart?nez, Edurne Amorena, Jes?s M Gonzalez-Santiago, Teresa Angueira, Virginia Flores, Samuel J Mart?nez-Dom?nguez, Manuel Pab?n-Carrasco, Benito Velayos, Alicia Algaba, Consuelo Ram?rez, Enrique Alfaro Almajano, Manuel Castro-Fernandez, Noelia Alcaide, Patricia Sanz Segura, Anna Cano-Català , Natalia Garc?a-Morales, Leticia Moreira, Francis Mégraud, Colm O’Morain, Xavier Calvet , Javier P Gisbert
Multivalent tyrosine kinase inhibition promotes T cell recruitment to immune-desert gastric cancers by restricting epithelial-mesenchymal transition via tumour-intrinsic IFN-γ signalling
Long Long Cao,1,2,3 Heng Lu,2 Mohammed Soutto,2 Nadeem Bhat,2 Zheng Chen,2,4 Dunfa Peng, 2 Ahmed Gomaa,2 Jia Bin Wang, 1 Jian Wei Xie,1 Ping Li,1 Chao Hui Zheng, 1,3 Sachiyo Nomura,5 Jashodeep Datta ,2,4 Nipun Merchant,2,4 Zhi Bin Chen,4,6 Alejandro Villarino,4,6 Alexander Zaika ,2,4,7 Chang Ming Huang ,1,3 Wael El-Rifai
Efficient plasma metabolic fingerprinting as a novel tool for diagnosis and prognosis of gastric cancer: a large-scale, multicentre study
Zhiyuan Xu,1,2 Yida Huang,3,4,5 Can Hu,1,2 Lingbin Du,6 Yi-An Du,1 Yanqiang Zhang,1 Jiangjiang Qin,1 Wanshan Liu, 3,4,5 Ruimin Wang,3,4,5 Shouzhi Yang,3,4,5 Jiao Wu,3,4,5 Jing Cao, 3,4,5 Juxiang Zhang,3,4,5 Gui- Ping Chen,7 Hang Lv, 8 Ping Zhao,9 Weiyang He,9 Xiaoliang Wang,10 Min Xu,11 Pingfang Wang,12 Chuanshen Hong,13 Li-Tao Yang,1 Jingli Xu, 1 Jiahui Chen ,1 Qing Wei,1 Ruolan Zhang,1 Li Yuan,1 Kun Qian,3,4,5 Xiangdong Cheng
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Marzieh Akhlaghpour,1,2 Talin Haritunians,1 Shyam K More,1 Lisa S Thomas,1 Dalton T Stamps, 1 Shishir Dube,1 Dalin Li, 1 Shaohong Yang,1 Carol J Landers,1 Emebet Mengesha, 1 Hussein Hamade ,1 Ramachandran Murali,2 Alka A Potdar, 1 Andrea J Wolf,1,2 Gregory J Botwin,1 Michelle Khrom,1 International IBD Genetics Consortium, Ashwin N Ananthakrishnan ,3 William A Faubion,4 Bana Jabri, 5 Sergio A Lira ,6 Rodney D Newberry,7 Robert S Sandler,8 R Balfour Sartor,8 Ramnik J Xavier,9 Steven R Brant,10 Judy H Cho ,11 Richard H Duerr,12 Mark G Lazarev, 13 John D Rioux,14 L Philip Schumm,15 Mark S Silverberg,16 Karen Zaghiyan,17 Phillip Fleshner, 17 Gil Y Melmed,1 Eric A Vasiliauskas,1 Christina Ha,1 Shervin Rabizadeh,18 Gaurav Syal, 1 Nirupama N Bonthala,1 David A Ziring,18 Stephan R Targan,1 Millie D Long,19 Dermot P B McGovern,1,2 Kathrin S Michelsen
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells
Karen Anne-Marie Ullrich ,1 Julia Derdau,1 Carsten Baltes,2 Alice Battistella,3 Gonzalo Rosso,3 Stefan Uderhardt ,4,5,6 Lisa Lou Schulze,1 Li- Juan Liu,1 Mark Dedden, 1 Marta Spocinska,1 Lucina Kainka,2 Markéta Kub?nkov?,3 Tanja Martina Müller ,1,6 Nina- Maria Schmidt,1 Emily Becker,1 Oumaima Ben Brahim,4,5,6 Imke Atreya ,1,6 Susetta Finotto,6,7 Iryna Prots,8 Stefan Wirtz, 1,6 Benno Weigmann ,1,6 Roc?o L?pez- Posadas ,1,6 Raja Atreya ,1,6 Arif Bülent Ekici,9 Franziska Lautenschl?ger,2,10 Jochen Guck,3 Markus F Neurath ,1,6 Sebastian Zundler
Persistent villous atrophy predicts development of complications and mortality in adult patients with coeliac disease: a multicentre longitudinal cohort study and development of a score to identify high-risk patients
Annalisa Schiepatti ,1,2 Stiliano Maimaris,1,2 Suneil A Raju,3 Olivia L Green,3 Giulia Mantica, 1 Amelie Therrien,4 David Flores- Marin,4 Justin Linden,4 Fernando Fern?ndez-Ba?ares ,5,6 Maria Esteve, 5,6 Daniel Leffler,4 Federico Biagi,1,2 David S Sanders
Gastrointestinal syndromes preceding a diagnosis of Parkinson’s disease: testing Braak’s hypothesis using a nationwide database for comparison with Alzheimer’s disease and cerebrovascular diseases
Bo Konings ,1 Luisa Villatoro,2 Jef Van den Eynde,3 Guillermo Barahona,2 Robert Burns,4 Megan McKnight,4 Ken Hui,4 Gayane Yenokyan,5 Jan Tack,1 Pankaj Jay Pasricha 2
Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cells
Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cells
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro
Marzia Rossi ,1 Andrea Vecchi, 2 Camilla Tiezzi,1 Valeria Barili,1 Paola Fisicaro ,2 Amalia Penna, 2 Ilaria Montali,1 Stephane Daffis, 3 Simon P Fletcher,3 Anuj Gaggar,3 Jonathan Medley, 3 Michael Graupe, 3 Latesh Lad,3 Alessandro Loglio,4 Roberta Soffredini, 4 Marta Borghi, 4 Teresa Pollicino, 5 Cristina Musolino,5 Arianna Alfieri, 2 Federica Brillo, 2 Diletta Laccabue,1 Marco Massari,6 Chiara Boarini,7 Gianluca Abbati, 7 Giuseppe Pedrazzi, 8 Gabriele Missale,1,2 Pietro Lampertico ,4,9 Carlo Ferrari, 1,2 Carolina Boni
Global prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus: an updated systematic review and meta-analysis
Elina En Li Cho ,1 Chong Zhe Ang, 1 Jingxuan Quek,2 Clarissa Elysia Fu,2 Lincoln Kai En Lim,2 Zane En Qi Heng,2 Darren Jun Hao Tan,2 Wen Hui Lim,2 Jie Ning Yong,2 Rebecca Zeng,2 Douglas Chee, 1 Benjamin Nah,1 Cosmas Rinaldi Adithya Lesmana, 3 Aung Hlaing Bwa, 4 Khin Maung Win ,4 Claire Faulkner, 5 Majd B Aboona ,5 Mei Chin Lim,2,6 Nicholas Syn,2 Anand V. Kulkarni ,7 Hiroyuki Suzuki ,8 Hirokazu Takahashi,9 Nobuharu Tamaki ,10,11 Karn Wijarnpreecha ,12 Daniel Q. Huang,1,2,13 Mark Muthiah ,1,2,13 Cheng Han Ng ,2 Rohit Loomba
From clinical variables to multiomics analysis: a margin morphology-based gross classification system for hepatocellular carcinoma stratification
Zhongqi Fan,1 Meishan Jin,2 Lei Zhang,3 Nanya Wang,4 Mingyue Li,1 Chuanlei Wang,1 Feng Wei, 1 Ping Zhang,1 Xiaohong Du,1 Xiaodong Sun,1 Wei Qiu,1 Meng Wang,1 Hongbin Wang,3 Xiaoju Shi, 1 Junfeng Ye,1 Chao Jiang,1 Jianpeng Zhou,1 Wengang Chai, 1 Jun Qi,1 Ting Li,1 Ruoyan Zhang,1 Xingkai Liu,1 Bo Huang,1 Kaiyuan Chai,1 Yannan Cao, 1 Wentao Mu, 1 Yu Huang,1 Tian Yang ,5 Huimao Zhang,3 Limei Qu,2 Yahui Liu,1 Guangyi Wang,1 Guoyue Lv
Different levels of healing in inflammatory bowel diseases: mucosal, histological, transmural, barrier and complete healing
Markus F Neurath ,1 Michael Vieth
APC mosaicism, not always isolated: two first-degree relatives with apparently distinct APC mosaicism
Diantha Terlouw ,1,2 Frederik J Hes, 3 Manon Suerink ,1 Arnoud Boot,4 Alexandra M J Langers,5 Carli M Tops, 1 Monique E van Leerdam,5 Christi J van Asperen,1 Steve G Rozen,4 Emilia K Bijlsma,1 Tom van Wezel,2 Hans Morreau, 2 Maartje Nielsen
Reply to Newman et al ‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’
Emad Mansoor, 1 Scott A Martin,2 Abe Perez,2 Vu Quang Nguyen,1 Jeffry A Katz,1 Shubham Gupta,3 Fabio Cominelli
On the ethics of digestive health research in historically marginalised communities
Christopher Vélez ,1 Laura E Targownik
Diameter of the shunt: the missing link in the appraisal of pTIPS in patients with cirrhosis with previous hepatic encephalopathy
Thierry Thevenot ,1 Maxime Desmarets ,2,3 Delphine Weil,1 Vincent Di Martino
Reply: Immortal time bias in a retrospective study examining colorectal cancer mortality according to adherence to colonoscopy
Manuel Zorzi ,1 Jessica Battagello, 2 Claudio Barbiellini Amidei
GI snapshot: weight loss and altered bowel habit in a 72-year-old woman
Lyman Lin ,1 Robert Gilmore, 1 Chamara Basnayake
Correction: Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)
Correction: Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma
