Acta Pharmacologica Sinica




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سفارش

ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery

Cheng-cen Guo, H. Eric Xu & Xiong MaÂ

doi : 10.1038/s41401-023-01134-2

Volume 44 Issue 11, November 2023

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Salvianolic acid B ameliorates retinal deficits in an early-stage Alzheimer’s disease mouse model through downregulating BACE1 and Aβ generation

Meng-dan Wang, Shuo Zhang, Xing-yang Liu, Pan-pan Wang, Yi-fan Zhu, Jun-rong Zhu, Chong-shan Lv, Shi-ying Li, Sui-feng Liu & Lei WenÂ

doi : 10.1038/s41401-023-01125-3

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A subthalamo-parabrachial glutamatergic pathway is involved in stress-induced self-grooming in mice

Tao Jia, Jing Chen, Ying-di Wang, Cheng Xiao & Chun-yi ZhouÂ

doi : 10.1038/s41401-023-01114-6

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Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function

Xin-xin Zhu, Xia Wang, Shi-yu Jiao, Ye Liu, Li Shi, Qing Xu, Jing-jing Wang, Yun-er Chen, Qi Zhang, Yan-ting Song, Ming Wei, Bao-qi Yu, Jens Fielitz, Frank J. Gonzalez, Jie Du & Ai-juan QuÂ

doi : 10.1038/s41401-023-01107-5

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Administration of A. muciniphila ameliorates pulmonary arterial hypertension by targeting miR-208a-3p/NOVA1 axis

Zheng-yi Bao, Hui-min Li, Shuo-bo Zhang, Yi-qiu Fei, Ming-fei Yao & Lan-juan LiÂ

doi : 10.1038/s41401-023-01126-2

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6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice

Ke Gong, Zhen Zhang, Sha-sha Chen, Xin-ran Zhu, Meng-yao Wang, Xin-yue Yang, Chen Ding, Ji-hong Han, Qing-shan Li & Ya-jun DuanÂ

doi : 10.1038/s41401-023-01121-7

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Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission

Xiao-long Li, Xue-wu Liu, Wei-ling Liu, Yu-quan Lin, Jing Liu, Yu-sheng Peng, Li-min Cheng & Yan-hua DuÂ

doi : 10.1038/s41401-023-01122-6

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mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development

Ya-fei Deng, Shu-ting Wu, Hong-yan Peng, Lei Tian, Ya-na Li, Yao Yang, Meng Meng, Lan-lan Huang, Pei-wen Xiong, Song-yang Li, Qing-lan Yang, Li-li Wang, Xiao-yao Li, Li-ping Li, Xiu-lan Lu, Xiao-hui Li, Yan-ling Wei, Zheng-hui Xiao, Jian-hua Yu & You-cai DengÂ

doi : 10.1038/s41401-023-01120-8

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Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection

Mei-qi Zhang 1 , Xin Jia 1 , Cui-qin Cheng 2 , Yu-xi Wang2 , Yi-ying Li2 , Ling-dong Kong 1 , Qi-qi Li1 , Fang Xie2 , Yan-li Yu 1 , Yu-ting He 1 , Qiu-tong Dong 1 , Zhan-hong Jia 1 , Yao Wang 2,3 ? and An-long Xu

doi : 10.1038/s41401-023-01111-9

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Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma

Joelle C. Boulos, Ejlal A. Omer, Daniela Rigano, Carmen Formisano, Manik Chatterjee, Ellen Leich, Sabine M. Klauck, Le-tian Shan & Thomas EfferthÂ

doi : 10.1038/s41401-023-01117-3

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ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to FGFR1 inhibitors through amino acid metabolic reprogramming

Zi-jian Zhang, Qi-fang Wu, An-qi Ren, Qian Chen, Jiang-zhou Shi, Jia-peng Li, Xi-yu Liu, Zhi-jie Zhang, Yu-zhe Tang, Yuan Zhao, Ning-ning Yao, Xiao-yu Zhang, Chang-peng Liu, Ge Dong, Jia-xuan Zhao, Mei-jun Xu, Yun-qiang Yue, Jia Hu, Fan Sun, Yu Liu, Qi-lin Ao, Fu-ling Zhou, Hong Wu, Tong-cun Zhang & Hai-chuan ZhuÂ

doi : 10.1038/s41401-023-01108-4

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Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway

Han-lin Wang, Jia-nan Li, Wei-juan Kan, Gao-ya Xu, Guang-hao Luo, Ning Song, Wen-biao Wu, Bo Feng, Jing-feng Fu, Yu-tong Tu, Min-min Liu, Ran Xu, Yu-bo Zhou, Gang Wei & Jia LiÂ

doi : 10.1038/s41401-023-01112-8

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Truncated SCRIB isoform promotes breast cancer metastasis through HNRNP A1 mediated exon 16 skipping

Bin Zhang 1,2,3 , Shao-han Xie 1,2,3 , Jun-yi Hu2,3 , Si-jia Lei1,2 , Liang-hua Shen 1,2 , Hong-tao Liu4 , Qing Zheng 1,2 , Zhi-ming Zhang 2 ?, Chun-lian Wu5 ?, Qiang Li 6,7 ? and Feng Wang

doi : 10.1038/s41401-023-01116-4

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Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities

Hua-ying Li, Yi-li Chen, Xiang-nan Deng, Huan-huan Li, Jie Tan, Guo-jian Liu, Yu-juan Zheng, Min Pei, Kai-ting Peng, Li-li Yue, Xiao-jia Chen, Yu Liu, Yong-shan Zhao & Chun-he WangÂ

doi : 10.1038/s41401-023-01118-2

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Gemcitabine-loaded synthetic high-density lipoprotein preferentially eradicates hepatic monocyte-derived macrophages in mouse liver with colorectal cancer metastases

Feng-qin Xiong, Wen Zhang, Chao Zheng, Yu Li, Xiang Gong, Yuan Zhang, Hao Wang, Peng-cheng Zhang & Ya-ping LiÂ

doi : 10.1038/s41401-023-01110-w

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Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model

Bi-rong Cao, Yi-ming Huang, Fu-yun Tian, Jin-hui Li, Chun-long Xu, Yu Wei, Ji-kai Liu, Qian-bei Guo, Hai-yan Xu, Li Zhan, Rui-min Lv, Yi-di Sun, Xin-de Hu, Zhao-bing Gao & Chang-yang ZhouÂ

doi : 10.1038/s41401-023-01115-5

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Author Correction: NRF2-GPX4/SOD2 axis imparts resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer cells

Chun-shuang Ma, Qian-ming Lv, Ke-ren Zhang, Ya-bin Tang, Yu-fei Zhang, Ying Shen, Hui-min Lei & Liang ZhuÂ

doi : 10.1038/s41401-023-01131-5

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