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Chemotherapy-induced metastasis: molecular mechanisms and clinical therapies
Jin-xuan Su, Si-jia Li, Xiao-feng Zhou, Zhi-jing Zhang, Yu Yan, Song-lin Liu & Qi QiÂ
doi : 10.1038/s41401-023-01093-8
Volume 44 Issue 9, September 2023
Inflachromene attenuates seizure severity in mouse epilepsy models via inhibiting HMGB1 translocation
Si-jie Dai, Yu-ying Shao, Yang Zheng, Jin-yi Sun, Zhi-sheng Li, Jia-ying Shi, Meng-qi Yan, Xiao-yun Qiu, Ceng-lin Xu, Wan-sang Cho, Masahiro Nishibori, Sihyeong Yi, Seung Bum Park, Yi Wang & Zhong ChenÂ
DHX9/DNA-tandem repeat-dependent downregulation of ciRNA-Fmn1 in the dorsal horn is required for neuropathic pain
Xiao-dan Liu, Tong Jin, Yang Tao, Ming Zhang, Hong-li Zheng, Qiao-qiao Liu, Ke-hui Yang, Ru-na Wei, Si-yuan Li, Yue Huang, Zhou-ya Xue, Ling-yun Hao, Qi-hui Wang, Li Yang, Fu-qing Lin, Wen Shen, Yuan-xiang Tao, Hong-jun Wang, Jun-li Cao & Zhi-qiang PanÂ
Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel
Qiao-qiao Wang, Long Wang, Wen-bo Zhang, Chun-ping Tang, Xue-qin Chen, Yue-ming Zheng, Sheng Yao, Zhao-bing Gao & Yang YeÂ
JMJD6 protects against isoproterenol-induced cardiac hypertrophy via inhibition of NF-κB activation by demethylating R149 of the p65 subunit
Zhen Guo, Yue-huai Hu, Guo-shuai Feng, Carla Valenzuela Ripoll, Zhen-zhen Li, Si-dong Cai, Qian-qian Wang, Wen-wei Luo, Qian Li, Li-ying Liang, Zhong-kai Wu, Ji-guo Zhang, Ali Javaheri, Lei Wang, Jing Lu & Pei-qing LiuÂ
Metrnl deficiency retards skin wound healing in mice by inhibiting AKT/eNOS signaling and angiogenesis
Tian-ying Xu, Sheng-li Qing, Jing-xin Zhao, Jie Song, Zhu-wei Miao, Jia-xin Li, Feng-yan Yang, Huan-yu Zhao, Si-li Zheng, Zhi-yong Li, Shu-na Wang & Chao-yu MiaoÂ
Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate
Xue-ling He, Jia-yun Chen, Yu-lin Feng, Ping Song, Yin Kwan Wong, Lu-lin Xie, Chen Wang, Qian Zhang, Yun-meng Bai, Peng Gao, Piao Luo, Qiang Liu, Fu-long Liao, Zhi-jie Li, Yong Jiang & Ji-gang WangÂ
Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis
Meng-jie Huang, Yu-wei Ji, Jian-wen Chen, Duo Li, Tian Zhou, Peng Qi, Xu Wang, Xiao-fan Li, Yi-fan Zhang, Xiang Yu, Ling-ling Wu, Xue-feng Sun, Guang-yan Cai, Xiang-mei Chen, Quan Hong & Zhe FengÂ
Aurantio-obtusin ameliorates obesity by activating PPARα-dependent mitochondrial thermogenesis in brown adipose tissues
Yi-jie Li, Rui-yu Wu, Run-ping Liu, Kai-yi Wu, Ming-ning Ding, Rong Sun, Yi-qing Gu, Fei Zhou, Jian-zhi Wu, Qi Zheng, Shu-ni Duan, Rong-rong Li, Yin-hao Zhang, Fang-hong Li & Xiaojiaoyang LiÂ
Activating Wnt/β-catenin signaling by autophagic degradation of APC contributes to the osteoblast differentiation effect of soy isoflavone on osteoporotic mesenchymal stem cells
Jing Ge, Ye-jia Yu, Jia-yi Li, Meng-yu Li, Si-mo Xia, Ke Xue, Shao-yi Wang & Chi YangÂ
Reducing lipid peroxidation attenuates stress-induced susceptibility to herpes simplex virus type 1
Jing-yu Weng, Xin-xing Chen, Xiao-hua Wang, Hui-er Ye, Yan-ping Wu, Wan-yang Sun, Lei Liang, Wen-jun Duan, Hiroshi Kurihara, Feng Huang, Xin-xin Sun, Shu-hua Ou-Yang, Rong-rong He & Yi-fang LiÂ
Bergapten inhibits NLRP3 inflammasome activation and pyroptosis via promoting mitophagy
Tong Luo, Xin Jia, Wan-di Feng, Jin-yong Wang, Fang Xie, Ling-dong Kong, Xue-jiao Wang, Rui Lian, Xia Liu, Ying-jie Chu, Yao Wang & An-long XuÂ
Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors
Szonja Anna Kovács, János Tibor Fekete & Balázs GyÅ‘rffyÂ
COPS6 promotes tumor progression and reduces CD8+ T cell infiltration by repressing IL-6 production to facilitate tumor immune evasion in breast cancer
Wen-qi Du, Zhi-man Zhu, Xin Jiang, Meng-jie Kang & Dong-sheng PeiÂ
TAX1BP1 contributes to deoxypodophyllotoxin-induced glioma cell parthanatos via inducing nuclear translocation of AIF by activation of mitochondrial respiratory chain complex I
Xuan-zhong Wang, Shi-peng Liang, Xi Chen, Zhen-chuan Wang, Chen Li, Chun-sheng Feng, Shan Lu, Chuan He, Yu-bo Wang, Guang-fan Chi & Peng-fei GeÂ
Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation
Yu-jia Xu, Kun Zeng, Ying Ren, Chen-yu Mao, Ying-hui Ye, Xiao-ting Zhu, Zi-ying Sun, Bi-yin Cao, Zu-bin Zhang, Guo-qiang Xu, Zhen-qian Huang & Xin-liang MaoÂ
Ceftazidime exhibits a broad inhibition to the infection of SARS-CoV-2 prototype and Omicron variant in vitro by blocking spike protein-ACE2 interaction
Yun-zhe Zheng, Zhao-yuan Liu, Yue Li, Xiao-ying Lv, Yi Wu, Meng-wen Huang, Xing-chao Pan, Jian-feng Chen & Chang-dong LinÂ
