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Editorial for the special issue on “Clinical reproductive immunology in China�
Dajin Li, Meirong Du, Aihua Liao, Aimin Zhao, Lianghui Diao
doi : 10.1111/aji.13705
The risk of intrauterine exposure to SARS-CoV-2 in female COVID-19 patients: A comprehensive review
Guo-hua Zhu, Lu Liu, Xi-xi Huang, Da-jin Li, Yi-zhun Zhu, Xin Lu, Mei-rong Du
doi : 10.1111/aji.13528
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that has caused fatal infectious diseases and global spread. This novel coronavirus attacks target cells through the interaction of spike protein and angiotensin-converting enzyme II (ACE2), leading to different clinical symptoms.
Anti-Ro/SSA and/or anti-La/SSB antibodies are associated with adverse endometrial status
Fangting Lu, Yanshi Wang, Xuhui Fang, Rentao Jin, Bo Xu, Qiannan Qiu, Li Wu
doi : 10.1111/aji.13630
Anti-Ro/SSA and/or anti-La/SSB (anti-SSA/SSB) antibodies impair pregnancy outcomes, including embryo implantation and pregnancy maintenance. Optimal endometrial immune status is essential for successful pregnancy.
Antiphosphatidylserine/prothrombin antibodies (aPS/PT) and risk of obstetric anti-phospholipid syndrome
Xiaoxin Zhang, Zhilan Liu, Feng Guo, Qiaohong Wang, Wenxin Bai, Aimin Zhao
doi : 10.1111/aji.13621
Assessment of the prevalence of anti-phosphatidylserine-prothrombin antibodies (aPS/PT) with OAPS and SN-OAPS in Chinese patients.
Clinical phenotype, treatment strategy and pregnancy outcome of non-criteria obstetric antiphospholipid syndrome
Jiapo Li, Yue Hou, Liyang Zhang, Fan Li, Qian Liu, Yuanyuan Li, Hongfei Shen, Ziyue Xiong, Ling Huang, Chong Qiao
doi : 10.1111/aji.13684
To illustrate the clinical features, treatment strategy, and pregnancy outcome of patients with obstetric antiphospholipid syndrome (OAPS), non-criteria obstetric antiphospholipid syndrome (NC-OAPS)
HLA-DR+ CD45RAˉ Tregs and CD28ˉ Treg-like cells: Potential immunologic biomarkers for reproductive aging
Kahindo P. Muyayalo, Su Song, Chunyan Liu, Guang-Shun Gong, Yu-Jing Zhang, Hui Zhou, Li Shen, Ai-Hua Liao
doi : 10.1111/aji.13591
This study aimed to identify subsets of regulatory T cells (Tregs) associated with ovarian aging and determine whether they can be used as markers of reproductive aging.
The predictive value of NKG2C+NK cells and LILRB1+NK cells in recurrent spontaneous abortion
Yue Hou, Qian Liu, Dazhong Jin, Jiapo Li, Ling Huang, Chong Qiao
doi : 10.1111/aji.13627
The maternal-fetal immune abnormalities can result in recurrent spontaneous abortion (RSA). The role of NKG2C+ and LILRB1+ pNK subsets in predicting pregnancy loss is uncertain.
Altered vitamin D metabolism is involved in the dysregulation of γδT cell function and their crosstalk with trophoblasts in recurrent pregnancy loss
Qian-Han Xu, Kahindo P. Muyayalo, Yu-Jing Zhang, Huan Wang, Xin-Xiu Lin, Ai-Hua Liao
doi : 10.1111/aji.13581
Recurrent pregnancy loss (RPL) is a common disease characterized by immune dysfunction and vitamin D deficiency. This study aimed to investigate vitamin D metabolism and γδT cell phenotypes at the maternal–fetal interface in women with early normal pregnancy (NP) and RPL and to determine the effects of vitamin D on the functions of γδT cells and their crosstalk with trophoblasts.
The cytokine profiles in follicular fluid and reproductive outcomes in women with endometriosis
Mu-Tian Han, Wei Cheng, Rui Zhu, Hui-Hua Wu, Jie Ding, Nan-Nan Zhao, Hong Li, Fu-Xin Wang
doi : 10.1111/aji.13633
Endometriosis patients undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment suffer from poor oocyte quality, a reduced likelihood of the fertilization rate, and low embryo quality. The dysregulation of immune cells and cytokine profiles in the follicular fluid (FF) may play an important role in the competence of the oocyte and the development of the embryo, but the mechanism remains largely unknown.
Integrated analysis of lncRNA and mRNA expression profiles in patients with unexplained recurrent spontaneous abortion
Xiaoli Zhu, Mengxuan Du, Heng Gu, Ruishan Wu, Mengge Gao, Hang Xu, Jia Tang, Mingzhen Li, Xiaohua Liu, Xingming Zhong
doi : 10.1111/aji.13691
Low dosage of prednisone acetate combined with doxycycline in the treatment of chronic endometritis in patients with repeated implantation failure
Yujie Zou, Lei Ming, Jinli Ding, Zhuoni Xiao, Saijiao Li, Jing Yang, Anyu Bao, Yan Zhang
doi : 10.1111/aji.13713
To retrospectively investigate whether the oral administration of prednisone acetate with doxycycline increases the cure rate of chronic endometritis (CE) and improves in vitro fertilization (IVF) outcomes in patients with repeated implantation failure (RIF) with CE.
Correction: Clinical outcome of intrauterine administration of peripheral mononuclear cells or human chorionic gonadotropin in unexplained implantation failure
doi : 10.1111/aji.13701
