دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Adenomyosis and uterine stiffness: what is the chicken? Which is the egg?
Malcolm G Munro
doi : 10.1093/humrep/dead046
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 527–528
Occupational factors and markers of testicular function among men attending a fertility center
Lidia MÃnguez-Alarcón, Paige L Williams, Irene Souter, Jennifer B Ford, Ramy Abou Ghayda, Russ Hauser, Jorge E Chavarro, for the Earth Study Team
doi : 10.1093/humrep/dead027
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 529–536
Semen quality has declined during recent decades and has been negatively correlated with higher risks of common chronic diseases and mortality, highlighting its public health importance beyond fertility and reproduction.
Dietary total antioxidant capacity and the risk of developing asthenozoospermia: a hospital-based case–control study in China
Donghui Huang, Yixiao Zhang, Xiaobin Wang, Renhao Guo, Xu Leng, Qiang Du, Qijun Wu, Bochen Pan, Yuhong Zhao
doi : 10.1093/humrep/dead010
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 537–548
Both diet and oxidative stress may be related to sperm quality; however, few studies have investigated the association between DTAC and sperm quality.
Usability, accuracy, and cost-effectiveness of a medical software for early pregnancies: a retrospective study
F Blavier, D Grobet, C Duflos, R Rayssiguier, N Ranisavljevic, M Duport Percier, A Rodriguez, C Blockeel, S Santos-Ribeiro, G Faron, L Gucciardo, F Fuchs
doi : 10.1093/humrep/dead025
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 549–559
Early pregnancy complications are responsible for a large percentage of consultations, mostly in emergency units, with guidelines becoming complex and poorly known/misunderstood by practitioners.
Progesterone for women with threatened miscarriage (STOP trial): a placebo-controlled randomized clinical trial
Lucas A McLindon, Gabriel James, Michael M Beckmann, Julia Bertolone, Kassam Mahomed, Monica Vane, Teresa Baker, Monique Gleed, Sandra Grey, Linda Tettamanzi, Ben Willem J Mol, Wentao Li
doi : 10.1093/humrep/dead029
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 560–568
Limited evidence has indicated that vaginal micronized progesterone may make little or no difference to the live birth rate when compared with placebo in women with threatened miscarriage. Subgroup analysis of one recent randomized trial reported that in women with bleeding and at least one previous miscarriage, progesterone might be of benefit.
A comparison of 12 machine learning models developed to predict ploidy, using a morphokinetic meta-dataset of 8147 embryos
Thomas Bamford, Christina Easter, Sue Montgomery, Rachel Smith, Rima K Dhillon-Smith, Amy Barrie, Alison Campbell, Arri Coomarasamy
doi : 10.1093/humrep/dead034
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 569–581
Morphokinetic timings have been demonstrated to be delayed in aneuploid embryos. Machine learning and statistical models are increasingly being built, however, until now they have been limited by data insufficiency.
Circulating maternal prorenin and oocyte and preimplantation embryo development: the Rotterdam Periconception Cohort
Rosalieke E Wiegel, A H Jan Danser, Linette van Duijn, Sten P Willemsen, Joop S E Laven, Eric A P Steegers, Esther B Baart, Régine P M Steegers-Theunissen
doi : 10.1093/humrep/dead030
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 582–595
After ovarian stimulation, circulating prorenin (renin’s precursor), is largely ovary-derived. Prorenin may contribute to ovarian angiotensin synthesis, which is relevant in reproduction given its role in follicular development and oocyte maturation.
A hybrid artificial intelligence model leverages multi-centric clinical data to improve fetal heart rate pregnancy prediction across time-lapse systems
A Duval, D Nogueira, N Dissler, M Maskani Filali, F Delestro Matos, L Chansel-Debordeaux, M Ferrer-Buitrago, E Ferrer, V Antequera, M Ruiz-Jorro, A Papaxanthos, H Ouchchane, B Keppi, P-Y Prima, G Regnier-Vigouroux, L Trebesses, C Geoffroy-Siraudin, S Zaragoza, E Scalici, P Sanguinet, N Cassagnard, C Ozanon, A De La Fuente, E Gómez, M Gervoise Boyer, P Boyer, E Ricciarelli, X Pollet-Villard, A Boussommier-Calleja
doi : 10.1093/humrep/dead023
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 596–608
Several AI-based algorithms have been developed to predict pregnancy, most of them based only on analysis of the time-lapse recording of embryo development. It remains unclear, however, whether considering numerous clinical features can improve the predictive performances of time-lapse based embryo evaluation.
Racial differences in transcriptomics and reactive oxygen species burden in myometrium and leiomyoma
Yinuo Li, Ross P McNally, Yue Feng, J Julie Kim, Jian-Jun Wei
doi : 10.1093/humrep/dead020
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 609–620
Black women develop uterine leiomyoma earlier than White women, and are more likely to be anemic, have multiple tumors, undergo hysterectomy at an earlier age, have a higher uterine weight, and report very severe pelvic pain.
Relation between adenomyosis and elastographic characteristics of the cervix
A Xholli, F Molinari, F Oppedisano, U Scovazzi, I Vacca, M G Schiaffino, E Cavalli, A Cagnacci
doi : 10.1093/humrep/dead014
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 621–628
An increased myometrial contractility during menses, leading to breaches in the endometrial basal lamina and subsequent infiltration of endometrial cells into the myometrium, has been proposed as a possible pathogenic mechanism for adenomyosis.
Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis
Piotr Laudański, Gabriela Rogalska, Damian Warzecha, Michał Lipa, Grzegorz Mańka, Mariusz Kiecka, Robert Spaczyński, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Młodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Toomas Neuman, Priit Adler, Hedi Peterson, Andres Salumets, Miroslaw Wielgos
doi : 10.1093/humrep/dead011
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 629–643
Various inflammatory factors are postulated to be involved in the pathomechanisms of endometriosis, and a potential link exists with autoimmune diseases, which may also play an important role. As the diagnosis of endometriosis remains invasive, it can only be confirmed using laparoscopy with histopathological examination of tissues.
The influence of avoidant attachment and perceived support on disclosure about involvement in donor-assisted conception to family and friends
Iolanda S Rodino, Katherine A Sanders
doi : 10.1093/humrep/dead019
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 644–654
Within the context of DAC, the topic of disclosure has been investigated in terms of the ‘if’, ‘when’, and the ‘how’ to disclose about circumstances of conception.
Linking human Dead end 1 (DND1) variants to male infertility employing zebrafish embryos
Kim Joana Westerich, Solveig Reinecke, Jana Emich, Margot Julia Wyrwoll, Birgit Stallmeyer, Matthias Meyer, Manon S Oud, Daniela Fietz, Adrian Pilatz, Sabine Kliesch, Michal Reichman-Fried, Katsiaryna Tarbashevich, Tamara Limon, Martin Stehling, Corinna Friedrich, Frank Tüttelmann, Erez Raz
doi : 10.1093/humrep/dead031
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 655–670
About 7% of the male population is affected by infertility but linking specific gene variants to the disease is challenging.
Regulation of human oocyte maturation in vivo during the final maturation of follicles
J Cadenas, L C Poulsen, D Nikiforov, M L Grøndahl, A Kumar, K Bahnu, A L M Englund, J Malm, G Marko-Varga, I Pla, A Sanchez, S E Pors, C Yding Andersen
doi : 10.1093/humrep/dead024
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 686–700
Many studies in animal species have provided insight into the mechanisms that govern the final maturation of oocytes. Currently, these studies have identified several different mechanisms downstream to the effects of FSH and LH.
Serum persistent organic pollutants and diminished ovarian reserve: a single-exposure and mixture exposure approach from a French case–control study
M Génard-Walton, C Warembourg, S Duros, F Mercier, T Lefebvre, A Guivarc’h-Levêque, M -T Le Martelot, B Le Bot, B Jacquemin, C Chevrier, S Cordier, N Costet, L Multigner, R Garlantézec
doi : 10.1093/humrep/dead028
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 701–715,
Animal studies have shown that several POPs can alter folliculogenesis and increase follicle depletion. However, only a few studies have been conducted in humans, with small sample sizes and inconsistent results.
Eight weeks of androgen priming by daily low-dose hCG injections before ICSI treatment in women with low ovarian reserve
N Friis Wang, J W Bogstad, S E Pors, M R Petersen, A Pinborg, C Yding Andersen, K Løssl
doi : 10.1093/humrep/dead012
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 716–725
The administration of androgens prior to OS might upregulate FSH receptor (FSHR) expression on granulosa cells, making follicles more responsive to exogenous FSH stimulation during OS. LH and hCG stimulate the local follicular androgen synthesis in theca cells and may be used as an endogenous androgen priming method.
Paraben exposure and couple fecundity: a preconception cohort study
Junjie Ao, Wei Qiu, Xiaona Huo, Yuqing Wang, Wenjuan Wang, Qianlong Zhang, Zhiwei Liu, Jun Zhang
doi : 10.1093/humrep/dead016
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 726–738
The reproductive toxicity of parabens, a class of widely used preservatives, has been suggested but evidence regarding their effects on couple fecundity is scarce.
Preimplantation genetic testing and child health: a national register-based study
Erica Ginström Ernstad, Charles Hanson, Kjell Wånggren, Ann Thurin-Kjellberg, Cecilia Hulthe Söderberg, Elisabeth Syk Lundberg, Max Petzold, Ulla-Britt Wennerholm, Christina Bergh
doi : 10.1093/humrep/dead021
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 739–750
PGT is offered to couples affected by monogenic disorders (PGT-M) or inherited chromosomal aberrations (PGT-SR), limiting the risk of transferring the disorder to the offspring.
Growth of twins conceived using assisted reproductive treatments up to 5 years old: a national growth cohort
Fiskani J M Kondowe, Peter Clayton, Matthew Gittins, Stephen W D’Souza, Daniel R Brison, Stephen A Roberts
doi : 10.1093/humrep/dead018
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 751–761
Singletons born from fresh ET grow more slowly in utero and in the first few weeks of life but then show postnatal catch-up growth by school age, compared to NC and FET babies.
Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses
S Caroselli, M Figliuzzi, L Picchetta, F Cogo, P Zambon, I Pergher, L Girardi, C Patassini, M Poli, D Bakalova, D Cimadomo, N Findikli, O Coban, M Serdarogullari, F Favero, S Bortolato, A Anastasi, F Capodanno, A Gallinelli, F Brancati, L Rienzi, F M Ubaldi, J Jimenez-Almazán, D Blesa-Jarque, J Miravet-Valenciano, C Rubio, C Simòn, A Capalbo
doi : 10.1093/humrep/dead033
Human Reproduction, Volume 38, Issue 4, April 2023, Pages 762–775
Standard methodologies employed in preimplantation genetic testing for aneuploidy (PGT-A) identify chromosomal aneuploidies but cannot determine ploidy level nor the presence of recurrent pathogenic MDs responsible for genomic disorders.
Correction to: Association between body mass index, weight loss and the chance of pregnancy in women with polycystic ovary syndrome and overweight or obesity: a retrospective cohort study in the UK
doi : 10.1093/humrep/dead037
Human Reproduction, Volume 38, Issue 4, April 2023, Page 776
