Acta Paediatrica, International Journal of Paediatrics




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Issue highlights

Anna Käll, Hugo Lagercrantz

doi : 10.1111/apa.16765

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Digital interventions could transform routine care but we need more research on how to achieve this

Marianne Therese Smogeli Holter

doi : 10.1111/apa.16715

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Hans Asperger: True or not?

Christopher Gillberg

doi : 10.1111/apa.16697

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Internet-based interventions for parents with children 0–5 years: A scoping review

Hege Therese Størksen, Silje Marie Haga, Karianne Thune Hammerstrøm, Heidi Jacobsen, Filip Drozd

doi : 10.1111/apa.16569

This study aims to review the existing literature on Internet-based health interventions directed to support parents of children aged 0–5 years.

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A scoping review of parental values during prenatal decisions about treatment options after extremely premature birth

Angret de Boer, Marieke de Vries, Dirk-Jan Berken, Hiske van Dam, E. Joanne Verweij, Marije Hogeveen, Rosa Geurtzen

doi : 10.1111/apa.16690

To describe what is known in the literature about parental perspectives in making prenatal decisions regarding treatment after birth at the limit of viability, as a better understanding of parental values can help professionals support parents as they decide.

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Capnometry during neonatal transport�Mini review

Hana Fucikova, Jan Blatny, Jan Stingl, Jan Miletin

doi : 10.1111/apa.16729

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Method considerations and study protocol for a Nordic multi-centre prospective study on outcomes in rare paediatric epilepsy surgery subgroups

Jesper Reinholdson, Kristina Malmgren, John Chaplin, Ingrid Olsson, Tove Hallböök

doi : 10.1111/apa.16691

Epilepsy surgery is a therapeutic option for selected children with drug-resistant epilepsy. Children who are surgical candidates have a high prevalence of neurodevelopmental comorbidities.

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How we handled our son's birth at the limits of viability after an unexpected pregnancy

Dirk-Jan Berken, Hiske van Dam

doi : 10.1111/apa.16692

In this paper, Dirk-Jan and Hiske, the parents of an infant born at 24 weeks of gestation, provide an insight into their experiences of their sons's birth and making decisions at the limit of viability.

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Immediate skin-to-skin contact after birth ensures stable thermoregulation in very preterm infants in high-resource settings

Karoline Lode-Kolz, Charlotte Hermansson, Agnes Linnér, Stina Klemming, Hanne Brit Hetland, Nils Bergman, Siri Lilliesköld, Hanne Markhus Pike, Björn Westrup, Wibke Jonas, Siren Rettedal

doi : 10.1111/apa.16590

To investigate the impact of immediate skin-to-skin contact with a parent after birth on thermal regulation in very preterm infants.

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Cortical activation and oxygen perfusion in preterm newborns during kangaroo mother care: A pilot study

Stefano Bembich, Elena Castelpietra, Gabriele Cont, Laura Travan, Julia Cavasin, Matteo Dolliani, Rosaria Traino, Sergio Demarini

doi : 10.1111/apa.16695

This study aimed to assess the functional activation of preterm newborns' cerebral cortex during kangaroo mother care. Possible effects of gestational age and previous kangaroo mother care experience were also considered.

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The gestational age significantly affects peripheral perfusion index value in low-altitude areas

Wei Hua, Ru-yi Zheng, Yan Xuan, Qu-ming Zhao, Yan Ren, Xue Hu, Zhi-xiu Wang, Jin-qiao Sun, Gesang Yangjin, Yalan Dou, Wei-li Yan, Xiao-jing Hu, Guo-ying Huang

doi : 10.1111/apa.16684

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NICU parents' mental health: A comparative study with parents of term and healthy infants

Christine Persson, Jenny Ericson, Raziye Salari, Mats H. Eriksson, Renée Flacking

doi : 10.1111/apa.16735

To compare mental health in parents of preterm/ill infants and parents of term and healthy infants before birth and 1 month after hospital discharge.

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Is neurally adjusted ventilatory assist feasible and safe in the extremely preterm infant?

Julie Lefevere, Filip Cools

doi : 10.1111/apa.16703

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Pulmonary important outcomes after extremely preterm birth: Parental perspectives

Emilie Thivierge, Thuy Mai Luu, Claude Julie Bourque, Keith J. Barrington, Rebecca Pearce, Magdalena Jaworski, Annie Janvier

doi : 10.1111/apa.16723

To describe pulmonary important outcomes (PIO) reported by parents of children born extremely preterm.

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High rate of insecure attachment patterns in preterm infants at early school age

Katrin Mehler, Eva Heine, Angela Kribs, Charlotte Schoemig, Lisa Reimann, Charlotte Nonhoff, Rüdiger Kissgen

doi : 10.1111/apa.16700

In preterm infants, insecure attachment is associated with behavioural and emotional problems but data on attachment beyond toddler age are scarce. This study assessed attachment security at 6–8 years in very and moderate or late preterm infants. The results were compared to a non-clinical full-term sample.

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Early postnatal weight loss does not affect the 2-year neurodevelopment in preterm infants of less than 32 weeks

Alessio Correani, Chiara Biagetti, Ilaria Burattini, Maria Paola Bellagamba, Rita D'Ascenzo, Enrica Ferretti, Anna Peretti, Chiara Monachesi, Manuela Simonato, Virgilio Carnielli

doi : 10.1111/apa.16720

It is still unclear if the magnitude of early postnatal weight loss (PWL) could be associated with neurodevelopmental outcomes in preterm infants. We studied the association between PWL and neurodevelopment at 2-year corrected age in preterm infants.

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Emotional and behavioural outcomes at 8 years of age in preterm-born children: A longitudinal study

Christos Tsakalidis, Dimitrios Rallis, Eftychia Drogouti, Kostantinos Kotsis, Konstantina Kapetaniou, Elisavet Diamanti

doi : 10.1111/apa.16722

To evaluate the predictive value of perinatal factors and neurodevelopmental evaluation in the emotional and behavioural outcomes in preterm-born children at 7–9 years of age.

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Childhood sleep health and epigenetic age acceleration in late adolescence: Cross-sectional and longitudinal analyses

David Balfour, Phillip E. Melton, Joanne A. McVeigh, Rae-Chi Huang, Peter R. Eastwood, Sian Wanstall, Amy C. Reynolds, Sarah Cohen-Woods

doi : 10.1111/apa.16719

Investigate if childhood measures of sleep health are associated with epigenetic age acceleration in late adolescence.

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Effects of prolonged sitting and physical activity breaks on measures of arterial stiffness and cortisol in adolescents

Maria Fernström, Emerald G. Heiland, Karin Kjellenberg, Marjan Ponten, Olga Tarassova, Gisela Nyberg, Björg Helgadottir, Maria M. Ekblom, Örjan Ekblom

doi : 10.1111/apa.16702

In adults, prolonged periods of sitting have been linked to acute negative effects on vascular structure and function. The aim of this study was to evaluate the acute effects of physical activity (PA) breaks during prolonged sitting on arterial stiffness, cortisol and psychological factors in adolescents.

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Almost half of children and adolescents had unmet need 6 months after their traumatic brain injury

Hilde Margrete Dahl, Ingvil Laberg Holthe, Marianne Løvstad, Cathrine Tverdal, Nada Andelic, Mia C. Myhre

doi : 10.1111/apa.16693

Very few studies have focused on how children with traumatic brain injuries (TBI) access and use publicly funded healthcare and educational services. We aimed to compare the symptoms, recovery and service use of children with TBIs and a control group with other traumatic injuries.

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Pregnancy- and birth-related risk factors for the development of childhood celiac disease

Pornthep Tanpowpong, Sijia Li, Janice A. Espinola, Ludmilla Candido Santos, Kaitlyn E. James, Camille E. Powe, Carlos A. Camargo Jr

doi : 10.1111/apa.16686

To evaluate whether pregnancy and birth-related factors are associated with celiac disease (CD) in a large, United States (US)-based mother-child cohort.

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‘The impact of the COVID-19 pandemic on the number of hospitalisations due to rotavirus infections’

Ewelina Gowin, Jakub Waliszewski, Kacper Maciejczak, Joanna SmektaÅ‚a, Zuzanna Urban, Patrycja WiÄ…cek, Adrianna Zaremba, Jacek Wysocki

doi : 10.1111/apa.16657

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Admissions for acute cardiac inflammatory events or chest pain before and after the severe acute respiratory syndrome coronavirus 2 was in circulation

Giorgio Sodero, Francesco Mariani, Francesco Proli, Ilaria Lazzareschi, Giulia Bersani, Angelica Bibiana Delogu, Gabriella De Rosa, Giuseppe Zampino, Piero Valentini, Danilo Buonsenso

doi : 10.1111/apa.16712

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Antibiotic prescriptions for child sinusitis varied between specialties after Finnish guidelines were updated in 2018

Matti Korppi, Sauli Palmu, Paula Heikkilä, Péter Csonka

doi : 10.1111/apa.16641

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Human bocavirus 1 epidemiology in children in relation to virus load and codetection

Elina Oldhoff, Rutger Bennet, Margareta Eriksson, Tobias Allander

doi : 10.1111/apa.16699

Human bocavirus 1 (HBoV1) has been associated with respiratory tract infections in children. We aimed at retrospectively describing patient characteristics, seasonality, pre-existing medical conditions, codetections, clinical manifestations and complications of HBoV1 infection in relation to viral load in the child population in Stockholm, with the overarching aim of elucidating the clinical significance of HBoV1.

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Repeated inflammatory markers may be useful for assessing febrile infants aged 29–90 days during early hospital surveillance

Tommaso Bellini, Riccardo Papa, Maria Grazia Calevo, Elena Fueri, Samuele Caruggi, Irene Bonato, Emanuela Piccotti

doi : 10.1111/apa.16682

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European study confirms the combination of fever and petechial rash as an important warning sign for childhood sepsis and meningitis

Benno Kohlmaier, Manuel Leitner, Nienke N. Hagedoorn, Dorine M. Borensztajn, Ulrich von Both, Enitan D. Carrol, Marieke Emonts, Michiel van der Flier, Ronald de Groot, Jethro Herberg, Michael Levin, Emma Lim, Ian K. Maconochie, Federico Martinon-Torres, Ruud G. Nijman, Marko Pokorn, Irene Rivero-Calle, Chantal D. Tan, Maria Tsolia, Clementien L. Vermont, Joany M. Zachariasse, Dace Zavadska, Henriette A. Moll, Werner Zenz, PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union)

doi : 10.1111/apa.16740

This study investigated febrile children with petechial rashes who presented to European emergency departments (EDs) and investigated the role that mechanical causes played in diagnoses.

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Bacterial resistance to commonly prescribed antibiotics was rare among children hospitalised for clinical dysentery

Regina Goldshtein, Nechama Sharon, Moshe Yana, Uri Rubinstein, Achiya Z. Amir

doi : 10.1111/apa.16717

Temporal changes in common pathogens that cause clinical dysentery have been described in Europe. We aimed to describe the distribution of pathogens and their antibiotic resistance in hospitalised Israeli children.

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Inpatient and outpatient treatment by specialist infant nutrition centres in Argentina effectively reduced child malnourishment

Flavia Eliana Santiano, Juan Manuel Fernandez-Muñoz, Virginia Pistone-Creydt, Felipe Carlos Martín Zoppino, Constanza Matilde López-Fontana, Rubén Walter Carón

doi : 10.1111/apa.16727

We evaluated the impact of inpatient and outpatient treatment provided by an infant nutrition foundation in Las Heras, Mendoza, Argentina and identified the factors that influenced nutritional recovery.

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High yield on aetiology using a systematic diagnostic approach to paediatric acute liver failure, analysis of a nationwide cohort

Thilde Nordmann Winther, Alex Yde Nielsen, Allan Lund, Fin Stolze Larsen, Marianne Hørby Jørgensen

doi : 10.1111/apa.16746

Paediatric acute liver failure (P-ALF) is a rare and devastating condition that leads to death or liver transplantation (LTx) in 40%–60% of cases.

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Respiratory insufficiency as a presenting symptom of congenital myasthenic syndromes

Fleur van den Udenhout, Peter Merkus, Sandra Verhaagen-van den Akker, Meyke Schouten, Corrie Erasmus, Hilde Braakman

doi : 10.1111/apa.16688

Respiratory insufficiency can be a presenting symptom of congenital myasthenic syndromes (CMS) but is rarely recognised as such. In this study, we aim to raise awareness of CMS to paediatricians.

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Twenty years' experience of immune thrombocytopenia and intracranial haemorrhage in the Nordic countries�A NOPHO study

Nadine G. Andersson, Birgitte Lausen, Annika MÃ¥rtensson, Ulf TedgÃ¥rd, Mimi Kjaersgaard, the NOPHO Platelet Working Group

doi : 10.1111/apa.16654

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A grounded theory study on the dynamics of parental grief during the children's end of life

Eline M. Kochen, Martha A. Grootenhuis, Saskia C. C. M. Teunissen, Paul A. Boelen, Maria-Luisa Tataranno, Jurrianne C. Fahner, Roos R. de Jonge, Michiel L. Houben, Marijke C. Kars, the emBRACE-working group

doi : 10.1111/apa.16716

Parents are increasingly confronted with loss during their child's end of life. Healthcare professionals struggle with parental responses to loss. This study aimed to understand parental coping with grief during their child's end of life.

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An assessment of what Hans Asperger knew about child euthanasia in Vienna during the Nazi occupation

Ernst Tatzer, Werner Maleczek, Franz Waldhauser

doi : 10.1111/apa.16571

Hans Asperger is probably best known for Asperger syndrome. However, he has been accused of knowingly and willingly participating in the National Socialist Child Euthanasia programme by referring patients to the Am Spiegelgrund children's home in Vienna. This later became notorious for euthanising disabled children. We investigated those allegations.

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Response to Tatzer et al: Their paper on what Asperger knew about Nazi ‘child euthanasia’ does not provide a rigorous assessment of the available evidence

Herwig Czech

doi : 10.1111/apa.16730

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Blood eosinophil levels in infants with bronchiolitis are predictive for adulthood asthma and lung function

Matti Korppi

doi : 10.1111/apa.16709

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Blood eosinophils during bronchiolitis were not associated with adult asthma in a Norwegian cohort study

Karen Galta Sørensen, Knut Øymar, Thomas Halvorsen, Ingvild Bruun Mikalsen

doi : 10.1111/apa.16710

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EBNEO commentary: Maternal high-dose DHA supplementation and neurodevelopment in infants born before 29 weeks' gestation

Deeva Vather, Amy Keir

doi : 10.1111/apa.16704

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EBNEO commentary: Oral versus intravenous sildenafil for pulmonary hypertension in neonates

Nilarni Jayakumar, Amy Keir

doi : 10.1111/apa.16725

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