Journal of Crohn's and Colitis




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سفارش

Multidisciplinary Perinatal Care in IBD

Lihi Godny, Vaios Svolos, Astrid-Jane Williams, Wladyslawa Czuber-Dochan, Marina Aloi, Ana Ibarra, Dearbhaile V O’Hanlon, Gabriele Dragoni, Irit Avni Biron, Marjo Campmans-Kuijpers, Paul Collins, Piotr Eder, Tamar Pfeffer-Gik, Susanna Jäghult, Catherine L Wall

doi : 10.1093/ecco-jcc/jjac189

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 663–680

Patients with inflammatory bowel disease [IBD] are often affected during their reproductive years and may have many perinatal queries that require the comprehensive perspectives of a multidisciplinary team [MDT].

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Association of Waist Circumference with the Risk of Inflammatory Bowel Disease: a Nationwide Cohort Study of 10 Million Individuals in Korea

Yeonjin Je, Kyungdo Han, Jaeyoung Chun, Yuna Kim, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jong Pil Im, Joo Sung Kim

doi : 10.1093/ecco-jcc/jjac193

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 681–692,

Metabolic syndrome may share the pathophysiology of adipose tissue dysregulation and inadequate immune response with inflammatory bowel disease [IBD]. We determined the association of abdominal obesity [AO] with the risk of developing IBD.

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Endoscopic Recurrence or Anastomotic Wound Healing Phenomenon after Ileocolic Resection for Crohn’s Disease: The Challenges of Accurate Endoscopic Scoring

Eline M L van der Does de Willebois, Marjolijn Duijvestein, Karin A Wasmann, Geert R A M D’Haens, Jarmila D W van der Bilt, Marco W Mundt, Roel Hompes, Manon van der Vlugt, Christianne J Buskens, Willem A Bemelman

doi : 10.1093/ecco-jcc/jjac175

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 693–699

Adequate endoscopic scoring in Crohn’s disease [CD] is crucial, as it dictates the need for initiating postoperative medical therapy and is utilized as an outcome parameter in clinical trials. Here we aimed to observe anastomotic wound healing in relation to endoscopic scoring of both inverted and everted stapled lines in side-to-side anastomoses.

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The Association of Inflammatory Bowel Disease with Coeliac Disease and Coeliac Autoimmunity in Children and Adults: A Nationwide Study from the epi-IIRN

Michal Kori, Yonatan Zamir, Sami Or Yermiyahu, Inessa Ainbinder, Svetlana Daichman, Gavriel David Pinto, Yiska Loewenberg Weisband, Shira Greenfeld, Revital Kariv, Natan Lederman, Eran Matz, Raanan Shamir, Iris Dotan, Dan Turner

doi : 10.1093/ecco-jcc/jjac176

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 700–705

Given the paucity of population-based data on the association between inflammatory bowel diseases [IBD], coeliac disease [CeD], and coeliac autoimmunity [CeA] we aimed to study the associations in a nationwide study.

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Increasing Incidence of Inflammatory Bowel Disease, with Greatest Change Among the Elderly: A Nationwide Study in Finland, 2000–2020

Kristi Kontola, Pia Oksanen, Heini Huhtala, Airi Jussila

doi : 10.1093/ecco-jcc/jjac177

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 706–711

The incidence of inflammatory bowel disease [IBD] is stabilising in many Western countries. Some still show increasing incidence. Our objective was to determine the latest trends in IBD incidence and prevalence in Finland and to compare these among different age groups and between different geographical areas.

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Long-term Colectomy Rates of Ulcerative Colitis over 40 Years of Different Therapeutic Eras–Results from a Western Hungarian Population-based Inception Cohort Between 1977 and 2020

Panu Wetwittayakhlang, Lorant Gonczi, Laszlo Lakatos, Zsuzsanna Kurti, Petra Golovics, Tunde Pandur, Gyula David, Zsuzsanna Erdelyi, Istvan Szita, Peter L Lakatos

doi : 10.1093/ecco-jcc/jjac188

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 712–721

Few populaion-based studies have investigated the long-term colectomy rates of ulcerative colitis [UC]. We aimed to assess the colectomy rates over 40 years of different therapeutic eras in a prospective population-based inception cohort from Veszprem Province, Western Hungary.

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Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series

Hussein Mahajna, Bram Verstockt, Daniel Bergemalm, Fabiana Castiglione, Fransisco Rodríguez-Moranta, Edoardo Savarino, Frank Hoentjen, Talat Bessissow, Jagoda Pokryszka, Anneline Cremer, Piotr Eder, Marie Truyens, Anat Yerushalmy-Feler, María José García, Uri Kopylov

doi : 10.1093/ecco-jcc/jjac179

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 722–727

Idiopathic thrombocytopaenic purpura [ITP] is an acquired haematological disorder with an incidence of 1–6 per 100 00/year. ITP and inflammatory bowel disease [IBD] comorbidity has been reported in the literature, but insights regarding the course, outcome and optimal management are limited by its rarity.

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Clinical and MRI Evolution After Local Injection of Bone Marrow-Derived Mesenchymal Stem Cells in Perianal Fistulae in Crohn’s Disease: Results From a Prospective Monocentric Study

Catherine Reenaers, Romain P Gillard, Carla Coimbra, René M Gillard, Paul Meunier, Chantal Lechanteur, Etienne Baudoux, Layla Boutaffala, Yves Beguin, Édouard Louis

doi : 10.1093/ecco-jcc/jjac192

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 728–737

Local injection of adipose tissue-derived mesenchymal stem cells [MSCs] is effective in fistulizing perianal Crohn’s disease [CD]. Less is known about bone marrow-derived MSCs and little is known about predictive factors of response and magnetic resonance imaging [MRI] evolution of the fistulae after MSC injection.

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Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease

Femke Crouwel, Melek Simsek, Marjon A de Boer, Chris J J Mulder, Emma M van Andel, Rob H Creemers, Dirk P van Asseldonk, Ad A van Bodegraven, Carmen S Horjus, Marijn C Visschedijk, Angelique L M Weusthuis, Margien L Seinen, Bindia Jharap, Fiona D M van Schaik, Ishfaq Ahmad, Paul J Boekema, Greetje J Tack, Louktje Wormmeester, Maurice W M D Lutgens, Petra G A van Boeckel, Lennard P L Gilissen, Marjon Kerkhof, Maurice G V M Russel, Frank Hoentjen, Maartje E Bartelink, Johan P Kuijvenhoven, Jeroen W J Maljaars, Willemijn A van Dop, Janneke Wonders, Michael M P J A van der Voorn, Hans J C Buiter, Nanne K de Boer

doi : 10.1093/ecco-jcc/jjac183

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 738–745

Safety of thioguanine in pregnant patients with inflammatory bowel disease [IBD] is sparsely recorded. This study was aimed to document the safety of thioguanine during pregnancy and birth.

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Diet Quality and Risk of Older-onset Crohn’s Disease and Ulcerative Colitis

Hamed Khalili, Niclas Hakansson, Kevin Casey, Emily Lopes, Jonas F Ludvigsson, Andrew T Chan, Simon S M Chan, Ola Olen, Alicja Wolk

doi : 10.1093/ecco-jcc/jjac184

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 746–753

We aimed to assess the relationship between diet quality and risk of older-onset Crohn’s disease [CD] and ulcerative colitis [UC].

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RNA Editing is a Valuable Biomarker for Predicting Carcinogenesis in Ulcerative Colitis

Kazutaka Takahashi, Kunitoshi Shigeyasu, Yoshitaka Kondo, Kazuyoshi Gotoh, Shuya Yano, Yuzo Umeda, Toshihiro Inokuchi, Caiming Xu, Kazuhiro Yoshida, Hibiki Umeda, Toshiaki Takahashi, Sho Takeda, Ryuichi Yoshida, Fuminori Teraishi, Hiroyuki Kishimoto, Yoshiko Mori, Kazuhiro Noma, Yoshinaga Okugawa, Sakiko Hiraoka, Hiroyuki Michiue, Hiroshi Tazawa, Osamu Matsushita, Ajay Goel, Toshiyoshi Fujiwara

doi : 10.1093/ecco-jcc/jjac186

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 754–766

Ulcerative colitis [UC] can lead to colitis-associated colorectal neoplasm [CAN]. Adenosine-to-inosine RNA editing, which is regulated by adenosine deaminase acting on RNA [ADAR], induces the post-transcriptional modification of critical oncogenes, including antizyme inhibitor 1 [AZIN1], leading to colorectal carcinogenesis. Therefore, we hypothesized that ADAR1 might be involved in the development of CAN in UC.

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Beyond Neutrophils for Predicting Relapse and Remission in Ulcerative Colitis

Hala El-Zimaity, Seth R Shaffer, Robert H Riddell, Rish K Pai, Charles N Bernstein

doi : 10.1093/ecco-jcc/jjac178

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 767–776

This study examines colonic histological features in ulcerative colitis [UC] in endoscopic remission to determine which cell types and biopsy sites best predict a patient’s likelihood of remaining in remission.

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Bidirectional Mendelian Randomisation Analysis Provides Evidence for the Causal Involvement of Dysregulation of CXCL9, CCL11 and CASP8 in the Pathogenesis of Ulcerative Colitis

Jie Chen, Yajing Zhou, Yuhao Sun, Shuai Yuan, Rahul Kalla, Jing Sun, Jianhui Zhao, Lijuan Wang, Xuejie Chen, Xuan Zhou, Siqi Dai, Yu Zhang, Gwo-tzer Ho, Dajing Xia, Qian Cao, Zhanju Liu, Susanna C Larsson, Xiaoyan Wang, Kefeng Ding, Jonas Halfvarson, Xue Li, Evropi Theodoratou, Jack Satsangi

doi : 10.1093/ecco-jcc/jjac191

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 777–785

Systemic inflammation is well recognised to be associated with ulcerative colitis [UC], but whether these effects are causal or consequential remains unclear. We aimed to define potential causal relationship of cytokine dysregulation with different tiers of evidence.

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Mucosal Addressin Cell Adhesion Molecule 1 Expression Reflects Mucosal Inflammation and Subsequent Relapse in Patients with Ulcerative Colitis

Kazuhiko Uchiyama, Tomohisa Takagi, Katsura Mizushima, Yasuko Hirai, Kohei Asaeda, Takeshi Sugaya, Mariko Kajiwara-Kubota, Saori Kashiwagi, Yuki Minagawa,, Yuma Hotta, Makoto Tanaka, Ken Inoue, Kazuhiro Katada, Kazuhiro Kamada, Takeshi Ishikawa, Hiroaki Yasuda, Hideyuki Konishi, Mitsuo Kishimoto, Yuji Naito, Yoshito Itoh

doi : 10.1093/ecco-jcc/jjac182

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 786–794

Mucosal addressin cell adhesion molecule 1 [MAdCAM-1] is upregulated in the vascular endothelium of the colonic mucosa in ulcerative colitis [UC]. Although the association between MAdCAM-1 expression and mucosal inflammation has been discussed, the association with the clinical course of UC patients has not been reported.

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Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease

Robert Battat, Ellen J Scherl, Dana Lukin, Paris Charilaou, Prerna Mahtani, Juliette Gerber, Jorge A Gandara, JRI IBD Live Cell Bank Consortium , Friederike Dündar, Paul Zumbo, Doron Betel, Chun-Jun Guo, Randy S Longman

doi : 10.1093/ecco-jcc/jjac173

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 795–803

Most Crohn’s disease [CD] patients require surgery. Ileitis recurs after most ileocolectomies and is a critical determinant for outcomes. The impacts of ileocolectomy-induced bile acid [BA] perturbations on intestinal microbiota and inflammation are unknown.

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Mass-Cytometry-Based Quantification of Global Histone Post-Translational Modifications at Single-Cell Resolution Across Peripheral Immune Cells in IBD

Lawrence Bai, Denis Dermadi, Laurynas Kalesinskas, Mai Dvorak, Sarah E Chang, Ananthakrishnan Ganesan, Samuel J S Rubin, Alex Kuo, Peggie Cheung, Michele Donato, Paul J Utz, Aida Habtezion, Purvesh Khatri

doi : 10.1093/ecco-jcc/jjac194

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 804–815

Current understanding of histone post-translational modifications [histone modifications] across immune cell types in patients with inflammatory bowel disease [IBD] during remission and flare is limited. The present study aimed to quantify histone modifications at a single-cell resolution in IBD patients during remission and flare and how they differ compared to healthy controls.

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Crohn-like Disease Affecting Small Bowel Due to Monogenic SLCO2A1 Mutations: First Cases of Chronic Enteropathy Associated with SLCO2A1 Gene [CEAS] in France

Annick Hamon, Dominique Cazals-Hatem, Carmen Stefanescu, Mathieu Uzzan, Xavier Treton, Alain Sauvanet, Yves Panis, Marie Monsinjon, Fanny Bonvalet, Olivier Corcos, Emilie Azouguene, Nadine Cerf-Bensussan, Yoram Bouhnik, Fabienne Charbit-Henrion

doi : 10.1093/ecco-jcc/jjac181

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Pages 816–820

Multiple chronic ulcers of small intestine are mainly ascribed to Crohn’s disease. Among possible differential diagnoses are chronic ulcers of small bowel caused by abnormal activation of the prostaglandin pathway either in the archetypal but uncommon non-steroidal anti-inflammatory drug [NSAID]-induced enteropathy, or in rare monogenic disorders due to PLA2G4A and SLCO2A1 mutations.

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Erratum to: Prevalence and Outcomes of COVID-19 Among Patients With Inflammatory Bowel Disease—A Danish Prospective Population-based Cohort Study

doi : 10.1093/ecco-jcc/jjac147

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Page 821

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Erratum to: Introduction of Subcutaneous Infliximab CT-P13 and Vedolizumab in Clinical Practice: A Multi-Stakeholder Position Statement Highlighting the Need for Post-Marketing Studies

doi : 10.1093/ecco-jcc/jjac174

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Page 822

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Corrigendum to: Efficacy and Outcomes of Faecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection in Children with Inflammatory Bowel Disease

doi : 10.1093/ecco-jcc/jjac195

Journal of Crohn's and Colitis, Volume 17, Issue 5, May 2023, Page 823

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