Enrichment of Patients With Ehlers Danlos Syndrome in Idiopathic Gastroparesis-A Gene Set Enrichment Analysis.

Smieszek, Sandra P. PhD 1; Carlin, Jesse L. PhD 1; Fisher, Michaela A. BS 1; Madonick, Darby S. BS 1; Kupersmith, Caleigh Q. BS 1; Moszczynski, Paula D. MA 1; Xiao, Changfu PhD 1; Polymeropoulos, Christos M. MD 1; Birznieks, Gunther MS 1; Polymeropoulos, Mihael H. MD 1

doi : 10.14309/ctg.0000000000000521

Volume 14(3) pgs. e00521-e00552 March 2023

Ehlers Danlos syndrome (EDS) is a heritable disorder of the connective tissue usually inherited as an autosomal dominant trait. We observe an enrichment of EDS cases in a gastroparesis clinical study.

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Bowel Preparation Efficacy and Safety of 1 L vs 2 L Polyethylene Glycol With Ascorbic Acid for Colonoscopy: A Randomized Controlled Trial.

Jeon, Han Jo MD, PhD 1; Keum, Bora MD, PhD 1; Bang, Eun Ju MD, MS 1; Lee, Kang Won MD, MS 1; Kim, Sang Hyun MD, PhD 1; Lee, Jae Min MD, PhD 1; Choi, Hyuk Soon MD, PhD 1; Kim, Eun Sun MD, PhD 1; Jeen, Yoon Tae MD, PhD 1; Lee, Hong Sik MD, PhD 1; Chun, Hoon Jai MD, PhD 1

doi : 10.14309/ctg.0000000000000532

Polyethylene glycol with ascorbic acid (PEG/Asc) is a well-established bowel preparation solution with guaranteed effectiveness and safety. A new low-volume agent, 1 L-PEG/Asc, has recently been released. This study aimed to compare the bowel cleansing efficacy and safety of 1 L-PEG/Asc and 2 L-PEG/Asc administered to adult outpatients in a split-dose manner.

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Preoperative Prognostic Nutritional Index and Nomogram for Predicting the Risk of Postoperative Complications in Patients With Crohn's Disease.

Zhang, Chen MD 1,*; Zhang, Tianyu MD 1,*; Shen, Ziyun MD 2; Zhong, Jie MD 1; Wang, Zhengting PhD 1

doi : 10.14309/ctg.0000000000000563

Patients with Crohn's disease (CD) are at a high risk of having postoperative complications. Preoperative prognostic nutritional index (PNI) has been extensively studied for postoperative complications in malignancies but seldom for CD.

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Safety and Efficacy of Split-Dose Thiopurine vs Low-Dose Thiopurine-Allopurinol Cotherapy in Pediatric Inflammatory Bowel Disease.

Cococcioni, Lucia MD 1,2; Pensabene, Licia MD, PhD 1,3; Puoti, Maria Giovanna MD 1; El-Kouly, Sara Ms 1; Chadokufa, Sibongile Ms 1; Buckingham, Raechel Ms 1; Gaynor, Edward MD 1; Saliakellis, Efstratios MD, PhD 1; Kiparissi, Fevronia MD 1,*; Borrelli, Osvaldo MD, PhD 1,*

doi : 10.14309/ctg.0000000000000544

Split-dose thiopurine and allopurinol-thiopurine cotherapy strategies have been suggested as rescue therapeutic options for children with inflammatory bowel disease (IBD) and impaired thiopurine metabolism.

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Practice Patterns and Outcomes of Patients With Retained Gastric Food Content Encountered During Endoscopy.

Lin, Emily MD 1; Gao, Yinglin DO 1; Wright, Andrew MD 1; Kim, John J. MD, MS 1

doi : 10.14309/ctg.0000000000000559

Retained gastric food content encountered during upper endoscopy may reduce diagnostic accuracy and increase the risk of aspiration. The aim of this study was to evaluate endoscopists' practice patterns and clinical outcomes in patients with retained gastric food content encountered during endoscopy.

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Complementary Effect of the Proportion of Overspeed Frames of Withdrawal and Withdrawal Time on Reflecting Colonoscopy Quality: A Retrospective, Observational Study.

Gong, Rongrong MM 1,2,3,*; Yao, Liwen MD 1,2,3,*; Zhang, Lihui MD 1,2,3,*; Li, Xun MD 1,2,3; Zhang, Jun MD 1,2,3; Li, Jiao MD 1,2,3; Jiang, Xiaoda MD 1,2,3; Zhao, Yu MD 1,2,3; Wang, Junxiao MM 1,2,3; Zhang, Chenxia MM 1,2,3; Wu, Huiling MD 1,2,3; Lu, Zihua MD 1,2,3; Mingkai Chen, PhD 1,2,3,+; Honggang Yu, PhD 1,2,3,+

doi : 10.14309/ctg.0000000000000566

Constructing quality indicators that reflect the defect of colonoscopy operation for quality audit and feedback is very important. Previously, we have established a real-time withdrawal speed monitoring system to control withdrawal speed below the safe speed.

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Association Between Opioid Use and Outpatient Visits for Dysphagia: An Analysis of the National Ambulatory Medical Care Survey in 2008-2018.

Flanagan, Ryan MD, MPH 1,2; Lopes, Emily W. MD 2,3; Glissen Brown, Jeremy R. MD 2,4; Tracy, Michaela S. MD 2,5; Chan, Walter W. MD, MPH 1,2

doi : 10.14309/ctg.0000000000000552

Opioid-induced esophageal dysfunction has been described with characteristic manometric patterns, but the population burden of dysphagia attributable to opioid use remains unclear.

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