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Editorial introductions
Editor(s): Budenz, Donald L.
doi : 10.1097/ICU.0000000000000738
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p v
Glaucoma care during the coronavirus disease 2019 pandemic
Vinod, Katekia,b; Sidoti, Paul A.a,b
doi : 10.1097/ICU.0000000000000730
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 75-82
The current article reviews the impact of the coronavirus disease 2019 (COVID-19) pandemic on the delivery of ophthalmic, and specifically, glaucoma care.
The role of clinical examination of the optic nerve head in glaucoma today
Sihota, Ramanjit; Sidhu, Talvir; Dada, Tanuj
doi : 10.1097/ICU.0000000000000734
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 83-91
The study was undertaken to assess the current importance of clinical examination of the optic nerve head (ONH) in glaucoma management.
Advances in perimetry for glaucoma
Prager, Alisa J.; Kang, J. Minjy; Tanna, Angelo P.
doi : 10.1097/ICU.0000000000000735
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 92-97
Perimetry remains important for the diagnosis and management of glaucoma despite advances in imaging technology. The purpose of this review is to describe advances in the acquisition and analysis of visual field data and highlight novel techniques for performing perimetry.
Recent developments in the use of optical coherence tomography for glaucoma
Vazquez, Luis E.a; Bye, Amandab; Aref, Ahmad A.b
doi : 10.1097/ICU.0000000000000733
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 98-104
The aim of this article is to summarize findings of recent reports highlighting the utility of novel optical coherence tomography (OCT) parameters in the diagnosis and monitoring of glaucomatous optic neuropathy.
Artificial intelligence and complex statistical modeling in glaucoma diagnosis and management
Salazar, Humbertoa; Misra, Vedantb; Swaminathan, Swarup S.a
doi : 10.1097/ICU.0000000000000741
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 105-117
The field of artificial intelligence has grown exponentially in recent years with new technology, methods, and applications emerging at a rapid rate. Many of these advancements have been used to improve the diagnosis and management of glaucoma. We aim to provide an overview of recent publications regarding the use of artificial intelligence to enhance the detection and treatment of glaucoma.
Pseudoexfoliation syndrome and glaucoma: from genes to disease mechanisms
Schl?tzer-Schrehardt, Ursulaa; Khor, Chiea Chuenb
doi : 10.1097/ICU.0000000000000736
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 118-128
The genetic basis of pseudoexfoliation (PEX) syndrome, the most common identifiable cause of open-angle glaucoma, is steadily being elucidated. This review summarizes the recent advances on genetic risk factors for PEX syndrome/glaucoma and their potential functional implications in PEX pathophysiology.
Advances in medical therapy for glaucoma
Ostler, Erika; Rhee, Douglasa; Burney, Edwarda; Sozeri, Yasemina
doi : 10.1097/ICU.0000000000000740
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 129-133
To discuss a new class of medication that has recently become available for the treatment of glaucoma; as well as share insights into developments in glaucoma medicine administration which has the potential to revolutionize medical therapy for glaucoma.
New strategies for the management of ocular surface disease in glaucoma patients
Voicu, Lauraa; Salim, Sarwatb
doi : 10.1097/ICU.0000000000000739
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 134-140
Glaucoma patients commonly suffer from ocular surface disease (OSD). As treatment strategies, medications and devices for the treatment of OSD as well as glaucoma surgical approaches evolve rapidly, it is important to consider their application to these patients.
Is laser trabeculoplasty the new star in glaucoma treatment?
T?teberg-Harms, Marca; Meier-Gibbons, Francesb
doi : 10.1097/ICU.0000000000000732
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 141-147
For decades, laser trabeculoplasty has been a well-proven therapeutic option in glaucoma management, and more recently, it has only gained in popularity. One reason for such popularity is that selective laser trabeculoplasty (SLT) is a therapy independent of patient adherence, which is typically low among glaucoma patients. Consequently, the number of studies on SLT has multiplied throughout the past years. This review provides an overview of studies on SLT from the last 12 months.
History, presence, and future of mitomycin C in glaucoma filtration surgery
Wolters, Jarno E.J.a,b,c; van Mechelen, Ralph J.S.a,b,c; Al Majidi, Ranaa,b,c; Pinchuk, Leonardd,e; Webers, Carroll A.B.a,b; Beckers, Henny J.M.a,b; Gorgels, Theo G.M.F.a,b
doi : 10.1097/ICU.0000000000000729
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 148-159
Mitomycin C (MMC) is an alkylating agent with extraordinary ability to crosslink DNA, preventing DNA synthesis. By this virtue, MMC is an important antitumor drug. In addition, MMC has become the gold standard medication for glaucoma filtration surgery (GFS). This eye surgery creates a passage for drainage of aqueous humor (AqH) out of the eye into the sub-Tenon's space with the aim of lowering the intraocular pressure. A major cause of failure of this operation is fibrosis and scarring in the sub-Tenon's space, which will restrict AqH outflow. Intraoperative application of MMC during GFS has increased GFS success rate, presumably mainly by reducing fibrosis after GFS. However, still 10% of glaucoma surgeries fail within the first year.
Safety profile of minimally invasive glaucoma surgery
Vinod, Katekia; Gedde, Steven J.b
doi : 10.1097/ICU.0000000000000731
Current Opinion in Ophthalmology: March 2021 - Volume 32 - Issue 2 - p 160-168
This article reviews the safety profile of trabecular meshwork/Schlemm's canal-based, subconjunctival, and suprachoroidal minimally invasive glaucoma surgery (MIGS).
