Radiotherapy and Oncology




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سفارش


The role of ESTRO guidelines in achieving consistency and quality in clinical radiation oncology practice

Birgitte Vrou Offersen a,b,c,⇑, Marianne C. Aznar d , Carol Bacchus e , Rob P. Coppes f , Eric Deutsch g , Dieter Georg h , Karin Haustermans i , Peter Hoskin j , Mechthild Krause k,l , Eric F. Lartigau m , Anne W.M. Lee n , Steffen Löck l , David I. Thwaites o,p , Albert J. van der Kogel q , Uulke van der Heide r , Vincenzo Valentini s , Jens Overgaard a , Michael Baumann

doi : 10.1016/j.radonc.2022.109446

Volume 179, February 2023, 109446

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Changes in pectoralis major stiffness and thickness following radiotherapy for breast cancer: A 12-month follow-up case series

Susann Wolfram a , Jamie Seul Ki Takayesu b , Lori Jo Pierce b , Reshma Jagsi b , David Benjamin Lipps

doi : 10.1016/j.radonc.2022.109450

Volume 179, February 2023, 109450

Radiotherapy (RT) is a common and often essential treatment for breast cancer, but has been associated with pectoralis major (PM) muscle fibrosis and atrophy. In an initial prospective evaluation, we assessed muscle stiffness and muscle thickness of the sternocostal and clavicular regions of the PM with ultrasound shear wave elastography and B-mode imaging.

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Clinical outcome after total neoadjuvant treatment (CAO/ARO/AIO-12) versus intensified neoadjuvant and adjuvant treatment (CAO/ARO/AIO-04) a comparison between two multicenter randomized phase II/III trials

doi : 10.1016/j.radonc.2022.109455

Volume 179, February 2023, 109455

Total neoadjuvant therapy (TNT) can enhance local tumor regression, but its survival benefits compared to intensified chemoradiotherapy (CRT) followed by adjuvant chemotherapy (CT) remain unclear.

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Metastatic patterns of level II-V cervical lymph nodes assessed per vertebral levels in nasopharyngeal carcinoma

Guang-Li Zhu a,b,1 , Xiao-Min Zhang a,c,1 , Kai-Bin Yang a,1 , Ling-Long Tang a,⇑, Jun Ma

doi : 10.1016/j.radonc.2022.109447

Volume 179, February 2023, 109447

The current cervical lymph nodes classification system is not perfectly reasonable for radiotherapy of nasopharyngeal carcinoma (NPC). This study aimed to determine the metastatic patterns of level II-V lymph nodes in NPC by using vertebrae as anatomical landmarks.

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Caudal distribution pattern of metastatic neck lymph nodes in nasopharyngeal carcinoma and prognostic significance of nodal spread distances

Yang Liu a , Ye Zhang a , Jingbo Wang a , Xiaodong Huang a , Kai Wang a , Yuan Qu a , Xuesong Chen a , Qingfeng Liu a , Jianghu Zhang a , Jingwei Luo a , Yexiong Li a , Runye Wu a,⇑, Junlin Yi

doi : 10.1016/j.radonc.2022.109443

Volume 179, February 2023, 109443

To investigate the caudal distribution pattern of metastatic neck lymph nodes (LNs) in nasopharyngeal carcinoma (NPC) and the prognostic significance of nodal spread distances (SDs).

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The valuable role of dynamic 18F FDG PET/CT-derived kinetic parameter in patients with nasopharyngeal carcinoma prior to radiotherapy: A prospective study

Xiaotao Huang a,b,1 , Mingzan Zhuang c,1 , Shuai Yang a,1 , Ying Wang d,1 , Qiaodan Liu a , Xiwei Xu a , Mei Xiao a , Yingpeng Peng a,b , Ping Jiang d , Wenhua Xu d , Shuanshuan Guo a , Rong Wang a,b , Wei Wei a,b , Guihua Zhong a,b , Yuling Zhou a,b , Shunli Peng a,b , Xuanzi Li a , Jianqi Cui a , Siyang Wang a , Yaqin Zhang e , Zhigang Liu a,b,f,

doi : 10.1016/j.radonc.2022.109440

Volume 179, February 2023, 109440

Dynamic positron emission tomography/computed tomography (PET/CT) served the potential role of characterizing malignant foci. The main objective of this prospective study was to explore the advantage of dynamic PET/CT imaging in characterizing nasopharyngeal carcinoma (NPC).

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Can the prognosis of individual patients with nasopharyngeal carcinoma be predicted using a routine blood test at admission?

Jing-rong Mao a,b,1 , Kai-qi Lan a,c,1 , Sai-lan Liu a,c,1 , Chen Liu b , Si-yi Xie a,c , Su-chen Li a,c , Wen-feng Ye b,2 , Xue-song Sun a,c,2 , Hai-qiang Mai

doi : 10.1016/j.radonc.2022.109445

Volume 179, February 2023, 109445

We sought to determine the prognostic value of a pre-treatment peripheral blood signature and the peripheral blood signature-based nomogram for patients with non-metastatic nasopharyngeal carcinoma (NPC).

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The relation between prediction model performance measures and patient selection outcomes for proton therapy in head and neck cancer

Artuur M. Leeuwenberg a,⇑, Johannes B. Reitsma a , Lisa G.L.J. Van den Bosch b , Jeroen Hoogland a , Arjen van der Schaaf b , Frank J.P. Hoebers c , Oda B. Wijers d , Johannes A. Langendijk b , Karel G.M. Moons a , Ewoud Schuit

doi : 10.1016/j.radonc.2022.109449

Volume 179, February 2023, 109449

Normal-tissue complication probability (NTCP) models predict complication risk in patients receiving radiotherapy, considering radiation dose to healthy tissues, and are used to select patients for proton therapy, based on their expected reduction in risk after proton therapy versus photon radiotherapy (ΔNTCP).

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SBRT focal dose intensification using an MR-Linac adaptive planning for intermediate-risk prostate cancer: An analysis of the dosimetric impact of intra-fractional organ changes

Victoria Sarah Brennan a,⇑, Sarah Burleson b , Caroline Kostrzewa c,1 , Paola Godoy Scripes b , Ergys Subashi b , Zhigang Zhang c , Neelam Tyagi b , Michael J. Zelefsky

doi : 10.1016/j.radonc.2022.109441

Volume 179, February 2023, 109441

Using an magnetic resonance linear accelerator (MR-Linac) may improve the precision of visible tumor boosting with ultra-hypofractionation by accounting for daily positional changes in the target and organs at risk (OAR).

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Conservation of pyramidal tract in radiosurgery for brain metastases of lung adenocarcinoma: Three-dimensional analysis of biologically effective dose

Ke Tang a,1,⇑, Nan Zhang b,1 , Xiaodong Yuan c,1 , Zenghui Qian d , Yang Li e , Xu Feng

doi : 10.1016/j.radonc.2022.109451

Volume 179, February 2023, 109451

Gamma knife surgery (GKS) for brain metastases (BMs) adjacent to the pyramidal tract (PT) is still a challenge to conduct. PT visualization and biologically effective dose (BED) calculation on a voxel-by-voxel basis may provide data to establish clinically safe values.

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External validation of a prediction model for timely implementation of innovations in radiotherapy

Rachelle R. Swart a,⇑, Rianne Fijten a , Liesbeth J. Boersma a , Petros Kalendralis a , Myra D. Behrendt c , Martijn Ketelaars b , Cheryl Roumen a , Maria J.G. Jacobs

doi : 10.1016/j.radonc.2022.109459

Volume 179, February 2023, 109459

The aim of this study was to externally validate a model that predicts timely innovation implementation, which can support radiotherapy professionals to be more successful in innovation implementation.

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Establishing quality indicators to comprehensively assess quality assurance and patient safety in radiotherapy and their relationship with an institution’s background

Norifumi Mizuno a,⇑, Hiroyuki Okamoto b , Toshiyuki Minemura c , Shinji Kawamura d , Naoki Tohyama e , Masahiko Kurooka f , Ryu Kawamorita g , Masaru Nakamura h , Yoshinori Ito i , Yoshiyuki Shioyama j , Hidefumi Aoyama k , Hiroshi Igaki

doi : 10.1016/j.radonc.2022.109452

Volume 179, February 2023, 109452

Quality indicators (QIs) for radiotherapy have been proposed by several groups, but no study has been conducted to correlate the implementation of indicators specific to patient safety over the course of the clinical process with an institution’s background

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Dosimetric feasibility of direct post-operative MR-Linac-based stereotactic radiosurgery for resection cavities of brain metastases

Enrica Seravalli a,⇑, Michelle Sierts a , Eric Brand a , Matteo Maspero a , Szabolcs David a , Mariellen E.P. Philippens a , Eduward H.J. Voormolen b , Joost J.C. Verhoeff

doi : 10.1016/j.radonc.2022.109456

Volume 179, February 2023, 109456

Post-operative radiosurgery (SRS) of brain metastases patients is typically planned on a post-recovery MRI, 2–4 weeks after resection. However, the intracranial metastasis may (re-)grow in this period. Planning SRS directly on the post-operative MRI enables shortening this time interval, anticipating the start of adjuvant systemic therapy, and so decreasing the chance of extracranial progression. The MRI-Linac (MRL) allows the simultaneous execution of the post-operative MRI and SRS treatment. The aim of this work was investigating the dosimetric feasibility of MRL-based post-operative SRS.

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