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Argument for Prompt Corneal Cross-Linking on Diagnosis of Keratoconus in a Pediatric Patient.
Henriquez, Maria A. MD, MSc, PhD
doi : 10.1097/ICO.0000000000003106
Volume 41(12) pgs. 1471-1599,e23-e28 December 2022
AB Strong evidence suggests that corneal crosslinking is a safe procedure capable of stopping or slowing down the progression of keratoconus, avoiding visual loss associated with progression, and delaying or preventing the need for corneal transplantation. The progressive and chronic nature of the disease makes the option for prompt crosslinking upon keratoconus diagnosis in a pediatric patient valid. Copyright (C) 2022 Wolters Kluwer Health, Inc. All rights reserved.
Childhood Corneal Cross-Linking: Follow-Up to Document Progression to Intervene.
Abad, Juan-Carlos MD
Strategies to Address Shortages of Intermediate-Term Cold Donor Corneal Storage Solution.
Li, Jennifer Y. MD
Selective Endothelialectomy in Peters Anomaly: A Novel Surgical Technique and Its Clinical Outcomes in Children.
Ramappa, Muralidhar MBBS, MS *,+,++; Chaurasia, Sunita MBBS, MS *,+,++; Mohamed, Ashik MBBS, MTech, PhD, MAMS *,[S]; Ramya Achanta, Divya Sree BS *,+,++; Mandal, Anil Kumar MBBS, MD, DNB, FAMS [P]; Edward, Deepak Paul MD, FACS, FARVO ||; Gokhale, Nikhil MBBS, MD, DNB **; Swarup, Rishi MBBS, DOMS, FRCS ++; Nischal, Ken K. MD, FAAP, FRCOphth ++++,[S][S]
doi : 10.1097/ICO.0000000000003134
This study describes the surgical outcomes of selective endothelialectomy in Peters anomaly (SEPA), a relatively new technique to manage Peters anomaly (PA). Methods: This study included 34 eyes of 28 children who had a visually significant posterior corneal defect due to PA and underwent SEPA between 2012 and 2019. A selective endothelialectomy from the posterior corneal defect was performed while preserving Descemet membrane.
Reproducibility and Reliability of Subbasal Corneal Nerve Parameters of the Inferior Whorl in the Neurotoxic and Healthy Cornea.
Chiang, Jeremy Chung Bo BOptom (Hons), BSc *; Khou, Vincent BOptom (Hons), BSc *,+; Tavakoli, Azadeh BOptom *; Park, Susanna B. PhD ++; Goldstein, David MD [S],[P]; Krishnan, Arun V. MBBS, PhD [S]; Markoulli, Maria MOptom, PhD *
doi : 10.1097/ICO.0000000000002947
The aim of this study was to investigate the reliability of subbasal corneal nerve plexus parameters of the inferior whorl compared with the central cornea with in vivo corneal confocal microscopy and to investigate the impact of inferior whorl pattern complexity on reproducibility. Methods: Subbasal corneal nerves of healthy controls (n = 10) and patients with chemotherapy-induced peripheral neuropathy (n = 10) were imaged with a laser scanning confocal microscope.
Prevalence and Impact of Cornea Guttata in the Graft After Penetrating Keratoplasty in Germany.
Schonit, Silvana; Maamri, Amine MD; Zemova, Elena MD; Munteanu, Cristian; Safi, Tarek MD; Daas, Loay MD; Seitz, Berthold MD, ML, FEBO
doi : 10.1097/ICO.0000000000002971
The aim of this study was to analyze the prevalence and severity of corneal guttata (CG) in grafts after penetrating keratoplasty (PKP) and to determine its clinical significance.
Management of Late Descemet's Membrane Detachment After Penetrating Keratoplasty in Keratoconus.
Weller, Julia M. MD; Kruse, Friedrich E. MD; Schloetzer-Schrehardt, Ursula PhD; Tourtas, Theofilos MD
doi : 10.1097/ICO.0000000000003027
The purpose of this study was to describe the feasibility of Descemet membrane endothelial keratoplasty (DMEK) as a treatment modality for spontaneous detachment of DM (DMD) decades after penetrating keratoplasty (PK) for keratoconus. Methods: We describe the clinical characteristics and therapeutic surgical approach in 6 eyes of 5 patients with DMD.
Acute Hydrops After Bowman Layer Transplantation for Keratoconus May Indicate that Descemet Membrane Rupture Is Secondary to Hydrops.
Musayeva, Aytan MD *; Santander-Garcia, Diana MD, PhD *,+; Quilendrino, Ruth MD *,+; Parker, Jack MD PhD ++; van Dijk, Korine PhD *,+; Henrat, Carole MD *; Dapena, Isabel MD, PhD *,+; Binder, Perry S. MD [S]; Melles, Gerrit R.J. MD, PhD *,+,[P]
doi : 10.1097/ICO.0000000000002920
The aim of this study was to review the postoperative course and imaging features of 7 eyes that presented with corneal hydrops after Bowman layer (BL) transplantation was performed for advanced keratoconus to determine the potential mechanisms of hydrops formation.
A Randomized Controlled Trial Comparing Microthin Descemet Stripping Automated Endothelial Keratoplasty With Descemet Membrane Endothelial Keratoplasty: Two-Year Report.
Pujari, Rathin MA (Cantab), MBBChir *; Matsou, Artemis MD, FEBO *; Kean, Jane Bsc, MOptom *; Zhang, Jufen PhD +; Rajan, Madhavan S. MD, FRCOphth *,+
doi : 10.1097/ICO.0000000000003024
The purpose of this study was to report the 2-year outcomes of a double-blinded randomized controlled trial comparing Descemet membrane endothelial keratoplasty (DMEK) and microthin Descemet stripping automated endothelial keratoplasty (MT-DSAEK). Methods: Fifty-six eyes of 56 patients were randomized to DMEK or microthin DSAEK (MT-DSAEK).
Posterior Corneal Curvature Changes After Pre-Descemet's Endothelial Keratoplasty: A Prospective Analysis.
Nidhi, Kavya MBBS, DNB; Ashok Kumar, Dhivya MD, FRCS, FICO, FAICO; Sinha, Nisha DOMS, DNB, FICO; Agarwal, Amar MS, FRCS, FRCOpth
doi : 10.1097/ICO.0000000000003033
To assess the changes in the posterior corneal curvature after pre-Descemet's endothelial keratoplasty (PDEK) and correlate with the visual outcomes. Methods: Eyes with pseudophakic bullous keratopathy, aphakic bullous keratopathy, and Fuchs dystrophy undergoing PDEK were included.
Combined Corneal Transplant, Glaucoma Drainage Implantation, and Pars Plana Vitrectomy Outcomes in a Pediatric Population.
Bohm, Kelley J. MD; Fernandez-Vega, Alvaro MD; Acaba-Berrocal, Luis MD; Chan, R. V. Paul MD; Cortina, M. Soledad MD
doi : 10.1097/ICO.0000000000002996
The combination of glaucoma drainage device (GDI), pars plana vitrectomy (PPV), and corneal transplantation is well reported in adults. However, little is known about the outcomes of such combined procedures in pediatric patients. We present a retrospective, single-center study to evaluate the safety and outcomes of concurrent GDI and/or PPV with corneal transplantation in patients 18 years and younger.
COVID-19 Vaccination May Not Increase Rates of Corneal Graft Rejection.
Busin, Massimo MD *,+,++; Zauli, Giorgio MD, PhD [S]; Pellegrini, Marco MD *,+,++; Virgili, Gianni MD [P],[forms double vertical]; Yu, Angeli Christy MD *,+,++
doi : 10.1097/ICO.0000000000003101
The aim of the study was to present the rates of rejection from 2018 to 2021 and evaluate the purported association between COVID-19 vaccination and corneal graft rejection.
Comparison of Graft Outcomes Reusing Original Intermediate-Term Cold Storage Solution for Entire Corneal Donor Storage Period With Exchanged Fresh Storage Solution After Donor Preparation in the Cornea Preservation Time Study.
Lass, Jonathan H. MD *,+,++; Bailey, Ryan J. MS [S]; Szczotka-Flynn, Loretta B. OD, PhD *; Benetz, Beth Ann MA *,+; Soper, Mark BS, CEBT [P]; Titus, Michael S. BS, CEBT ++; Kollman, Craig PhD [S]; Beck, Roy W. MD, PhD [S]; On behalf of the Cornea Preservation Time Study Group
doi : 10.1097/ICO.0000000000003108
The purpose of this study was to evaluate outcomes of Descemet stripping automated endothelial keratoplasty comparing exchange with fresh intermediate-term cold storage solution after lenticule preparation versus reuse of the original solution in the Cornea Preservation Time Study.
Comprehensive Analysis of circRNA-Associated-ceRNA Networks in Human Corneal Endothelial Dysfunction.
Qiu, Ji-ni MD *,+; Shan, Kun MD, PhD *,+; Xiang, Jun MD, PhD *,+; Gu, Jia-yu BM *; Zhou, Rong-mei MD, PhD *,+; Zhang, Xue-ling MS *,+; Zhang, Chao-ran MD, PhD *,+; Xu, Jian-jiang MD, PhD *,+
doi : 10.1097/ICO.0000000000003065
Circular RNAs (circRNAs) are a novel class of endogenous noncoding RNAs that regulate gene expression through the competitive endogenous RNA (ceRNA) mechanism. CircRNA-associated-ceRNA networks are closely related to oxidative stress-related diseases. Oxidative stress-induced dysfunction of the corneal endothelium (CE) is a major pathological feature in many corneal diseases.
Effect of Increasing Povidone-Iodine Exposure on Corneal Epithelium and Impact on Donor Rim Cultures.
Sawant, Onkar B. PhD *,+; How, Stephanie MS, MBA *; Hurlbert, Susan CEBT +; Titus, Michael S. CEBT +; Vadakkepattath, Indu ME +; Shen, Xiang PhD ++; Djalilian, Ali R. MD ++
doi : 10.1097/ICO.0000000000003057
The purpose of this study was to assess the effect of a second povidone-iodine (PVP-I) application at the time of donor tissue recovery on overall tissue quality and to analyze the rate of positive fungal and bacterial rim cultures before and after implementing increased PVP-I exposure.
Analysis of SARS-CoV-2 in Corneal Tissue of Deceased Asymptomatic Novel Coronavirus Disease 2019 Donors.
Mahalingam, Karthikeyan MD *; Angmo, Dewang FRCS, FICO *; Kakkar, Aanchal MD +; Bafna, Rahul Kumar MD *; Sharma, Tushar MBBS *; Rai, Aishwarya MSc +; Agrawal, Sahil MD *; Dar, Lalit MD ++; Saxena, Rohit MD *; Titiyal, Jeewan S. MD *; Sharma, Namrata FRCOphth, FRCSEd *
doi : 10.1097/ICO.0000000000003127
The aim of this study was to analyze the presence of the SARS-CoV-2 virus in the corneal tissue of asymptomatic deceased novel coronavirus disease 2019 (COVID-19) patients.
Presbyopic Corneal Inlay Extrusion Consequent to Sterile Keratolysis: Surgical Revision and Long-Term Management.
Kanellopoulos, Anastasios John MD *,+
doi : 10.1097/ICO.0000000000002982
The purpose of this study was to report a serious complication of early sterile keratolysis associated with a presbyopia inlay implantation combined with hyperopic laser in situ keratomileusis (LASIK).
Severe Acute Respiratory Syndrome Coronavirus 2-Associated Blepharoconjunctivitis and Erythema Multiforme-Like Rash in a Young Man.
Fernandez, Karen B. MD; Sioufi, Kareem MD; Aker, Jon E. MD; Mercer, Ryan N. MD
doi : 10.1097/ICO.0000000000002848
The aim of this study was to describe the diagnosis and management of bilateral blepharoconjunctivitis and erythema multiforme (EM)-like illness in an otherwise healthy young man who tested positive for severe acute respiratory syndrome coronavirus (SARS-CoV)-2.
Clinical Registries in Dry Eye Disease: A Systematic Review.
Khoo, Pauline BSc (Hons), PhD *; Downie, Laura E. BOptom, PhD +; Stapleton, Fiona PhD ++; Rauz, Saaeha PhD [S]; Daien, Vincent MD, PhD [P]; Arnalich, Francisco MD, PhD ||; Mingo, David MD, PhD ||; Watson, Stephanie L. PhD *
doi : 10.1097/ICO.0000000000003139
The objective of this study was to undertake a systematic review of the literature reporting on clinical registries in dry eye disease (DED).
Glaucoma in Patients With Endothelial Keratoplasty.
Saini, Chhavi MD; Davies, Emma C. MD; Chodosh, James MD, MPH; Shen, Lucy Q. MD
doi : 10.1097/ICO.0000000000003122
AB Endothelial keratoplasty (EK), including Descemet stripping endothelial keratoplasty and Descemet membrane endothelial keratoplasty, is now the most performed corneal transplant procedure in the United States. Intraocular pressure (IOP) elevation and glaucoma are common complications and can cause irreversible vision loss and corneal graft failure.
Descemet Membrane Endothelial Keratoplasty in a Patient With Descemet Membrane Detachment and Rieger-Like Anomaly Associated With Osteogenesis Imperfecta and Mutation in COL1A1.
Trigaux, Celine MD; Borrelli, Maria MD, PhD; Geerling, Gerd MD; Menzel-Severing, Johannes MD, PhD
Glaucoma Evaluation and Management in Eyes with Boston Type 1 and Aurolab Keratoprostheses in an Indian Cohort.
Bhambra, Nishaant MD, CM *; Harissi-Dagher, Mona MD, FRCSC +
Reply.
Senthil, Sirisha MBBS, MS, FRCS *; Mohamed, Ashik MBBS, MTech, PhD, MAMS +; Shanbhag, Swapna S. MBBS, MS ++; Durgam, Shravya Sri BS +; Bagga, Bhupesh MBBS, MS, FRCS ++; Sangwan, Virender S. MBBS, MS [S]; Basu, Sayan MBBS, MS ++
Eusol-C as Corneal Cold Storage Solution: Early Clinical Outcomes of Keratoplasty.
Koo, Ellen H. MD *; Goodman, Courtney F. BS *; Vanner, Elizabeth E. PhD *; Tothova, Jana D. PhD +; Fout, Elizabeth MHSA ++; Buras, William BS, CEBT ++
