Journal of the American Society of Nephrology : JASN




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This Month's Highlights

doi : 10.1681/ASN.2022020203

April 2022; Volume 33,Issue 4

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New Insights into the Pivotal Roles of Claudins in Proximal Tubule Electrolyte Reabsorption

Peter S. Aronson

doi : 10.1681/ASN.2022020157

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Endocytosis Begins inside the Cell

Andrew Beenken

doi : 10.1681/ASN.2022020155

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The Search for the Perfect Agent for Anemia Management in Chronic Kidney Disease

Francesco Locatelli and Lucia Del Vecchio

doi : 10.1681/ASN.2022020173

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Premature Death in Kidney Transplant Recipients: The Time for Trials is Now

Amanda J. Vinson, Sunita Singh, Steven Chadban, David Cherney, Osama Gaber, John S. Gill, Erika Helgeson, Charles A. Herzog, Meg Jardine, Vivekanand Jha, Bertram L. Kasiske, Roslyn B. Mannon, Erin D. Michos, Amy K. Mottl, Kristin Newby, Prabir Roy-Chaudhury, Deirdre Sawinski, Adnan Sharif, Vikas S. Sridhar, Katherine R. Tuttle, David M. Vock and Arthur Matas

doi : 10.1681/ASN.2021111517

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The Non-Inferiority Complex: What Do Non-Inferiority Trials Tell Us?

Magdalene M. Assimon, Gary R. Cutter and Joanne M. Bargman

doi : 10.1681/ASN.2021050681

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The Impact of Vaccination on Incidence and Outcomes of SARS-CoV-2 Infection in Patients with Kidney Failure in Scotland

Samira Bell, Jacqueline Campbell, Emilie Lambourg, Chrissie Watters, Martin O’Neil, Alison Almond, Katharine Buck, Edward J. Carr, Laura Clark, Zoe Cousland, Mark Findlay, Nicola Joss, Wendy Metcalfe, Michaela Petrie, Elaine Spalding, Jamie P. Traynor, Vinod Sanu, Peter Thomson, Shona Methven and Patrick B. Mark

doi : 10.1681/ASN.2022010046

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Comparative Effectiveness of mRNA-based BNT162b2 Vaccine versus Adenovirus Vector–Based Ad26.COV2.S Vaccine for the Prevention of COVID-19 among Dialysis Patients

Steven M. Brunelli, Scott Sibbel, Steph Karpinski, Gilbert Marlowe, Adam G. Walker, Jeffrey Giullian, David Van Wyck, Tara Kelley, Rachael Lazar, Meredith L. Zywno, Jeffrey J. Connaire, Amy Young and Francesca Tentori

doi : 10.1681/ASN.2021101395

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Claudin-10a Deficiency Shifts Proximal Tubular Cl- Permeability to Cation Selectivity via Claudin-2 Redistribution

Tilman Breiderhoff, Nina Himmerkus, Luca Meoli, Anja Fromm, Sebastian Sewerin, Natalia Kriuchkova, Oliver Nagel, Yury Ladilov, Susanne M. Krug, Catarina Quintanova, Meike Stumpp, Dieter Garbe-Schönberg, Ulrike Westernströer, Cosima Merkel, Merle Annette Brinkhus, Janine Altmüller, Michal R. Schweiger, Dominik Müller, Kerim Mutig, Markus Morawski, Jan Halbritter, Susanne Milatz, Markus Bleich and Dorothee Günzel

doi : 10.1681/ASN.2021030286

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A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome

Anissa A. Widjaja, Shamini G. Shekeran, Eleonora Adami, Joyce G Wei Ting, Jessie Tan, Sivakumar Viswanathan, Sze Yun Lim, Puay Hoon Tan, Norbert Hübner, Thomas Coffman and Stuart A. Cook

doi : 10.1681/ASN.2021040577

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A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness

Naomi Issler, Sara Afonso, Irith Weissman, Katrin Jordan, Alberto Cebrian-Serrano, Katrin Meindl, Eileen Dahlke, Konstantin Tziridis, Guanhua Yan, José M. Robles-López, Lydia Tabernero, Vaksha Patel, Anne Kesselheim, Enriko D. Klootwijk, Horia C. Stanescu, Simona Dumitriu, Daniela Iancu, Mehmet Tekman, Monika Mozere, Graciana Jaureguiberry, Priya Outtandy, Claire Russell, Anna-Lena Forst, Christina Sterner, Elena-Sofia Heinl, Helga Othmen, Ines Tegtmeier, Markus Reichold, Ina Maria Schiessl, Katharina Limm, Peter Oefner, Ralph Witzgall, Lifei Fu, Franziska Theilig, Achim Schilling, Efrat Shuster Biton, Limor Kalfon, Ayalla Fedida, Elite Arnon-Sheleg, Ofer Ben Izhak, Daniella Magen, Yair Anikster, Holger Schulze, Christine Ziegler, Martin Lowe, Benjamin Davies, Detlef Böckenhauer, Robert Kleta, Tzipora C. Falik Zaccai and Richard Warth

doi : 10.1681/ASN.2021101312

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A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice

Cheng J. Song, Zhang Li, Ummey Khalecha Bintha Ahmed, Sarah J. Bland, Alex Yashchenko, Shanrun Liu, Ernald J. Aloria, Jeremie M. Lever, Nancy M. Gonzalez, Marisa A. Bickel, Cory B. Giles, Constantin Georgescu, Jonathan D. Wren, Mark L. Lang, Etty N. Benveniste, Laurie E. Harrington, Leo Tsiokas, James F. George, Kenneth L. Jones, David K. Crossman, Anupam Agarwal, Michal Mrug, Bradley K. Yoder, Katharina Hopp and Kurt A. Zimmerman

doi : 10.1681/ASN.2021030278

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Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation

Sarah R. McLarnon, Katie Wilson, Bansari Patel, Jingping Sun, Christina L. Sartain, Christopher D. Mejias, Jacqueline B. Musall, Jennifer C. Sullivan, Qingqing Wei, Jian-Kang Chen, Kelly A. Hyndman, Brendan Marshall, Haichun Yang, Agnes B. Fogo and Paul M. O’Connor

doi : 10.1681/ASN.2021081089

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α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier

Manuel Rogg, Jasmin I. Maier, Clara Van Wymersch, Martin Helmstädter, Alena Sammarco, Maja Lindenmeyer, Paulina Zareba, Eloi Montanez, Gerd Walz, Martin Werner, Nicole Endlich, Thomas Benzing, Tobias B. Huber and Christoph Schell

doi : 10.1681/ASN.2021101319

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Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease

Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou, Christelle Veyrat-Durebex, Carolyn Heckenmeyer, Marylise Fernandez, Lena Berchtold, Delal Dalga, Clemens Cohen, Maarten Naesens, Sven-Erik Ricksten, Pierre-Yves Martin, Jérôme Pugin, Franck Merlier, Karsten Haupt, Joseph M. Rutkowski, Solange Moll, Pietro E. Cippà, David Legouis and Sophie de Seigneux

doi : 10.1681/ASN.2021050680

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Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study

Fredrik Uhlin, Wladimir Szpirt, Andreas Kronbichler, Annette Bruchfeld, Inga Soveri, Lionel Rostaing, Eric Daugas, Arnaud Lionet, Nassim Kamar, Cédric Rafat, Marek Myslive�ek, Vladimír Tesař, Anders Fernström, Christian Kjellman, Charlotte Elfving, Stephen McAdoo, Johan Mölne, Ingeborg Bajema, Elisabeth Sonesson and Mårten Segelmark

doi : 10.1681/ASN.2021111460

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Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada

Matthew J. Oliver, Doneal Thomas, Shabnam Balamchi, Jane Ip, Kyla Naylor, Stephanie N. Dixon, Eric McArthur, Jeff Kwong, Jeffrey Perl, Mohammad Atiquzzaman, Joel Singer, Angie Yeung, Michelle Hladunewich, Kevin Yau, Amit X. Garg, Jerome A. Leis, Adeera Levin, Mel Krajden and Peter G. Blake

doi : 10.1681/ASN.2021091262

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Roxadustat Versus Epoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis: Results from the Randomized Phase 3 ROCKIES Study

Steven Fishbane, Carol A. Pollock, Mohamed El-Shahawy, Elizabeth T. Escudero, Anjay Rastogi, Bui Pham Van, Lars Frison, Mark Houser, Maksym Pola, Dustin J. Little, Nicolas Guzman and Pablo E. Pergola

doi : 10.1681/ASN.2020111638

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Advanced Tertiary Lymphoid Tissues in Protocol Biopsies in Kidney Transplant Recipients: Addressing Additional Methods To Detect Intragraft B Cells

Romy du Long, Sandrine Florquin and Jesper Kers

doi : 10.1681/ASN.2021111509

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Authors’ Reply: Advanced Tertiary Lymphoid Tissues in Protocol Biopsies in Kidney Transplant Recipients: Addressing Additional Methods To Detect Intragraft B Cells

Yuki Sato, Yu Ho Lee, Keisuke Taniguchi, Takahisa Yoshikawa, Peter Boor, Jürgen Floege and Motoko Yanagita

doi : 10.1681/ASN.2021121588

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SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?

Veerle Wijtvliet, Karl Martin Wissing, Daniel Abramowicz and Kristien J. Ledeganck

doi : 10.1681/ASN.2021121566

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Authors’ Reply: SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?

Eva Schrezenmeier, Arne Sattler, Fabian Halleck and Klemens Budde

doi : 10.1681/ASN.2022010033

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Correction: Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity

doi : 10.1681/ASN.2022010083

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