Annals of Neurology




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Annals of Neurology: Volume 91, Number 6, June 2022

doi : 10.1002/ana.26114

Volume 91, Issue 6

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Regulatory Approval in ALS; When Is a Single Study Enough?

Merit E. Cudkowicz MD, Jeremy M. Shefner MD, PhD

doi : 10.1002/ana.26371

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Prolonged Unconsciousness is Common in COVID-19 and Associated with Hypoxemia

Greer Waldrop MD, ScM, Seyed A. Safavynia MD, PhD, Megan E. Barra PharmD, Sachin Agarwal MD, MPH, David A. Berlin MD, Amelia K Boehme PhD, MSPH, Daniel Brodie MD, Jacky M. Choi MPH, Kevin Doyle MA, Joseph J. Fins MD, Wolfgang Ganglberger MSc, Katherine Hoffman MS, Aaron M. Mittel MD, David Roh MD, Shibani S. Mukerji MD, PhD, Caroline Der Nigoghossian PharmD, Soojin Park MD, Edward J. Schenck MD, John Salazar-Schicchi MD, Qi Shen PhD, Evan Sholle MS, Angela G. Velazquez MD, Maria C. Walline MD, M. Brandon Westover MD, PhD, Emery N. Brown MD, PhD, Jonathan Victor MD, PhD, Brian L. Edlow MD, Nicholas D. Schiff MD, Jan Claassen MD

doi : 10.1002/ana.26342

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Neurological Events Reported after COVID-19 Vaccines: An Analysis of Vaccine Adverse Event Reporting System

Jennifer A. Frontera MD, Arina A. Tamborska MD, Mohamed F. Doheim MBBCh, David Garcia-Azorin MD, PhD, Hasim Gezegen MD, Alla Guekht MD, PhD, Abdul Hanif Khan Yusof Khan MMed, Michele Santacatterina PhD, James Sejvar MD, Kiran T. Thakur MD, Erica Westenberg MSc, Andrea S. Winkler MD, PhD, Ettore Beghi MD, contributors from the Global COVID-19 Neuro Research Coalition

doi : 10.1002/ana.26339

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SARS-CoV-2 and Mitochondrial Proteins in Neural-Derived Exosomes of COVID-19

Michael J. Peluso MD, Steven G. Deeks MD, Maja Mustapic PhD, Dimitrios Kapogiannis MD, Timothy J. Henrich MD, Scott Lu MBBS, Sarah A. Goldberg BA, Rebecca Hoh MS, Jessica Y. Chen, Enrique O. Martinez BA, J. Daniel Kelly MD, PhD, Jeffrey N. Martin MD, Edward J. Goetzl MD

doi : 10.1002/ana.26350

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Cellular and Humoral Immunity to SARS-CoV-2 Infection in Multiple Sclerosis Patients on Ocrelizumab and Other Disease-Modifying Therapies: A Multi-Ethnic Observational Study

Ilya Kister MD, Yury Patskovsky PhD, Ryan Curtin BS, Jinglan Pei PhD, Katherine Perdomo BA, Zoe Rimler BS, Iryna Voloshyna PhD, Marie I. Samanovic PhD, Amber R. Cornelius MS, Yogambigai Velmurugu PhD, Samantha Nyovanie MPhil, Joseph J. Kim MS, Ethan Tardio BS, Tamar E. Bacon BA, Lana Zhovtis Ryerson MD, Pranil Raut MS, Rosetta Pedotti PhD, Kathleen Hawker MD, Catarina Raposo PhD, Jessica Priest PharmD, Mark Cabatingan PhD, Ryan C. Winger PhD, Mark J. Mulligan MD, Michelle Krogsgaard PhD, Gregg J. Silverman MD

doi : 10.1002/ana.26346

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Severe Acute Respiratory Syndrome Coronavirus 2 Third Vaccine Immune Response in Multiple Sclerosis Patients Treated with Ocrelizumab

Livnat Brill PhD, Catarina Raposo PhD, Ariel Rechtman BSc, Omri Zveik BMedSc, Netta Levin MD, PhD, Esther Oiknine-Djian PhD, Dana G. Wolf MD, PhD, Adi Vaknin-Dembinsky MD, PhD

doi : 10.1002/ana.26343

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Human CASPR2 Antibodies Reversibly Alter Memory and the CASPR2 Protein Complex

Bastien Joubert MD, PhD, Mar Petit-Pedrol PhD, Jesús Planagumà PhD, Francesco Mannara PhD, Marija Radosevic PhD, Maria Marsal PhD, Estibaliz Maudes MSc, Anna García-Serra PhD, Esther Aguilar BS, Alba Andrés-Bilbé PhD, Xavier Gasull PhD, Pablo Loza-Alvarez PhD, Lidia Sabater PhD, Myrna R. Rosenfeld MD, PhD, Josep Dalmau PhD

doi : 10.1002/ana.26345

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Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS

Johanna Oechtering MD, Therese Lincke MD, Sabine Schaedelin Msc, Bernhard F. Décard MD, Aleksandra Maceski Msc, Annette Orleth PhD, Stephanie Meier Msc, Eline Willemse PhD, Arabella Buchmann Msc, Michael Khalil MD, Tobias Derfuss MD, Pascal Benkert PhD, Ingmar Heijnen PhD, Axel Regeniter MD, Stefanie Müller MD, Lutz Achtnichts MD, Patrice Lalive MD, Anke Salmen MD, Caroline Pot MD, Claudio Gobbi MD, Ludwig Kappos MD, Cristina Granziera MD PhD, David Leppert MD, Regina Schlaeger MD, Johanna M. Lieb MD, Jens Kuhle MD PhD, and for the Swiss MS Cohort Study

doi : 10.1002/ana.26348

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Nonpermissive Skin Environment Impairs Nerve Regeneration in Diabetes via Sec31a

Hung-Wei Kan PhD, Jung-Hsien Hsieh MD, PhD, Shih-Wei Wang MD, PhD, Ti-Yen Yeh PhD, Ming-Fong Chang PhD, Tsz-Yi Tang MD, Chi-Chao Chao MD, PhD, Fang-Ping Feng MS, Sung-Tsang Hsieh MD, PhD

doi : 10.1002/ana.26347

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Caffeine Consumption and Dementia: Are Lewy Bodies the Link?

Marilyn C. Cornelis PhD, David A. Bennett MD, Sandra Weintraub PhD, Julie A. Schneider MD, Martha Clare Morris PhD

doi : 10.1002/ana.26349

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APOE Antibody Inhibits Aβ-Associated Tau Seeding and Spreading in a Mouse Model

Maud Gratuze PhD, Hong Jiang MD, Chanung Wang PhD, Monica Xiong PhD, Xin Bao MS, David M. Holtzman MD

doi : 10.1002/ana.26351

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Effects of Alzheimer and Lewy Body Disease Pathologies on Brain Metabolism

Young-gun Lee MD, PhD, Seun Jeon PhD, Mincheol Park MD, Sung Woo Kang MD, So Hoon Yoon MD, Kyoungwon Baik MD, Phil Hyu Lee MD, PhD, Young Ho Sohn MD, PhD, Byoung Seok Ye MD, PhD, the Alzheimer's Disease Neuroimaging Initiative

doi : 10.1002/ana.26355

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Greater Diffusion Restriction in White Matter in Preclinical Alzheimer Disease

Andreana Benitez PhD, Jens H. Jensen PhD, Kathryn Thorn BS, Siddhartha Dhiman MS, Stephanie Fountain-Zaragoza PhD, William J. Rieter MD, PhD, Maria Vittoria Spampinato MD, Eric D. Hamlett PhD, Paul J. Nietert PhD, Maria de Fatima Falangola MD, PhD, Joseph A. Helpern PhD

doi : 10.1002/ana.26353

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Tmax Volumes Predict Final Infarct Size and Functional Outcome in Ischemic Stroke Patients Receiving Endovascular Treatment

Enrico Fainardi MD, PhD, Giorgio Busto MD, Andrea Rosi MD, Elisa Scola MD, Ilaria Casetta MD, Andrea Bernardoni MD, Andrea Saletti MD, Francesco Arba MD, Patrizia Nencini MD, Nicola Limbucci MD, Salvatore Mangiafico MD, Andrew Demchuk MD, Mohammed A Almekhlafi MD, MSc, Mayank Goyal MD, Ting Y. Lee PhD, Bijoy K. Menon MD, MSc, Andrea Morotti MD

doi : 10.1002/ana.26354

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Unilateral Leukoencephalopathy Revealing Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Cédric Gollion, Hélène Morel, Fabrice Bonneville

doi : 10.1002/ana.26337

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The 4-Copy Conundrum in the Treatment of Infants with Spinal Muscular Atrophy

Stella Deng MD, Bo Hoon Lee MD, Emma Ciafaloni MD, Samuel J. Mackenzie MD, PhD

doi : 10.1002/ana.26358

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Reply to: The 4-Copy Conundrum in the Treatment of Infants with Spinal Muscular Atrophy

Crystal J. J. Yeo MD, PhD, Zachary Simmons MD, Darryl C. De Vivo MD, Basil T. Darras MD

doi : 10.1002/ana.26357

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