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Introduction: Standards of Medical Care in Diabetes—2022
American Diabetes Association
doi : 10.2337/dc22-Sint
Professional Practice Committee: Standards of Medical Care in Diabetes—2022
American Diabetes Association
doi : 10.2337/dc22-Sppc
Summary of Revisions: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-Srev
1. Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S001
2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S002
3. Prevention or Delay of Type 2 Diabetes and Associated Comorbidities: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S003
4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S004
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S005
6. Glycemic Targets: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S006
7. Diabetes Technology: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S007
8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S008
9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S009
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S010
11. Chronic Kidney Disease and Risk Management: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S011
12. Retinopathy, Neuropathy, and Foot Care: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S012
13. Older Adults: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S013
14. Children and Adolescents: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S014
15. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S015
16. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S016
17. Diabetes Advocacy: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee
doi : 10.2337/dc22-S017
Here’s to 100 Years of Insulin and Science—and More to Come!
Matthew C. Riddle
doi : 10.2337/dci21-0013
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases
William T. Cefalu; Dana K. Andersen; Guillermo Arreaza-RubÃn; Christopher L. Pin; Sheryl Sato; C. Bruce Verchere; Minna Woo; Norman D. Rosenblum; on behalf of the symposium planning committee, moderators, and speakers
doi : 10.2337/dci21-0051
The Noble and Often Nobel Role Played by Insulin-Focused Research in Modern Medicine
Victor S. Harrison; Mahfuzul H. Khan; Christine E. Chamberlain; David M. Harlan
doi : 10.2337/dci21-0012
The Life and Times of Dr. Robert Sherwin, One of the Greatest of Great Diabetes Investigators
William V. Tamborlane
doi : 10.2337/dci21-0036
High-Normal Protein Intake Is Not Associated With Faster Renal Function Deterioration in Patients With Type 2 Diabetes: A Prospective Analysis in the DIALECT Cohort
Milou M. Oosterwijk; Dion Groothof; Gerjan Navis; Stephan J.L. Bakker; Gozewijn D. Laverman
doi : 10.2337/dc21-1211
Emotional Correlates of the COVID-19 Pandemic in Individuals With and Without Diabetes
Barbara A. Myers; Rachel Klingensmith; Mary de Groot
doi : 10.2337/dc21-0769
Characteristics of Workplace Psychosocial Resources and Risk of Diabetes: A Prospective Cohort Study
Tianwei Xu; Alice J. Clark; Jaana Pentti; Reiner Rugulies; Theis Lange; Jussi Vahtera; Linda L. Magnusson Hanson; Hugo Westerlund; Mika Kivimäki; Naja H. Rod
doi : 10.2337/dc20-2943
Traveling Across Time Zones With Type 1 Diabetes: A Pilot Study Comparing Insulin Degludec With Insulin Glargine U100
Wendy C. Bevier; Kristin N. Castorino; Ceara Axelrod; Gal Haroush; Christian C. Farfan; Nina Shelton; Kristen Nelson; Lisa A. Spink; Hanqing Liu; David Kerr
doi : 10.2337/dc21-1524
Changes in the Prevalence of Symptoms of Depression, Loneliness, and Insomnia in U.S. Older Adults With Type 2 Diabetes During the COVID-19 Pandemic: The Look AHEAD Study
Ariana M. Chao; Thomas A. Wadden; Jeanne M. Clark; Kathleen M. Hayden; Marjorie J. Howard; Karen C. Johnson; Blandine Laferrère; Jeanne M. McCaffery; Rena R. Wing; Susan Z. Yanovski; Lynne E. Wagenknecht; the Look AHEAD Research Group
doi : 10.2337/dc21-1179
Foot Ulcer and Risk of Lower Limb Amputation or Death in People With Diabetes: A National Population-Based Retrospective Cohort Study
Rosemary C. Chamberlain; Kelly Fleetwood; Sarah H. Wild; Helen M. Colhoun; Robert S. Lindsay; John R. Petrie; Rory J. McCrimmon; Fraser Gibb; Sam Philip; Naveed Sattar; Brian Kennon; Graham P. Leese
doi : 10.2337/dc21-1596
Minimum Threshold of Bariatric Surgical Weight Loss for Initial Diabetes Remission
Douglas Barthold; Elizabeth Brouwer; Lee J. Barton; David E. Arterburn; Anirban Basu; Anita Courcoulas; Cecelia L. Crawford; Peter N. Fedorka; Heidi Fischer; Benjamin B. Kim; Edward C. Mun; Sameer B. Murali; Kristi Reynolds; Tae K. Yoon; Robert E. Zane; Karen J. Coleman
doi : 10.2337/dc21-0714
Hypoglycemic and Hyperglycemic Crises Among U.S. Adults With Diabetes and End-stage Kidney Disease: Population-Based Study, 2013–2017
Rodolfo J. Galindo; Mohammed K. Ali; Shealeigh A. Funni; Andrew B. Dodge; Shaheen S. Kurani; Nilay D. Shah; Guillermo E. Umpierrez; Rozalina G. McCoy
doi : 10.2337/dc21-1579
The Impact of Racial and Ethnic Health Disparities in Diabetes Management on Clinical Outcomes: A Reinforcement Learning Analysis of Health Inequity Among Youth and Young Adults in the SEARCH for Diabetes in Youth Study
Anna R. Kahkoska; Teeranan Pokaprakarn; G. Rumay Alexander; Tessa L. Crume; Dana Dabelea; Jasmin Divers; Lawrence M. Dolan; Elizabeth T. Jensen; Jean M. Lawrence; Santica Marcovina; Amy K. Mottl; Catherine Pihoker; Sharon H. Saydah; Michael R. Kosorok; Elizabeth J. Mayer-Davis
doi : 10.2337/dc21-0496
Diabetic Peripheral Neuropathy and Urological Complications in Type 1 Diabetes: Findings From the Epidemiology of Diabetes Interventions and Complications Study
Rodica Pop-Busui; Barbara H. Braffett; Hunter Wessells; William H. Herman; Catherine L. Martin; Alan M. Jacobson; Aruna V. Sarma; for the DCCT/EDIC Research Group
doi : 10.2337/dc21-1276
Glycemic Control and Risk of Sepsis and Subsequent Mortality in Type 2 Diabetes
Anca Balintescu; Marcus Lind; Mikael Andersson Franko; Anders Oldner; Maria Cronhjort; Ann-Marie Svensson; Björn Eliasson; Johan Mårtensson
doi : 10.2337/dc21-1050
Risk of Incident Dementia According to Glycemic Status and Comorbidities of Hyperglycemia: A Nationwide Population-Based Cohort Study
Woo Jung Kim; Seo Jung Lee; Eun Lee; Eun Y. Lee; Kyungdo Han
doi : 10.2337/dc21-0957
30-Year Cardiovascular Disease in Type 1 Diabetes: Risk and Risk Factors Differ by Long-term Patterns of Glycemic Control
Rachel G. Miller; Trevor J. Orchard; Tina Costacou
doi : 10.2337/dc21-1381
Gestational Diabetes Mellitus and the Risks of Overall and Type-Specific Cardiovascular Diseases: A Population- and Sibling-Matched Cohort Study
Yongfu Yu; Melissa Soohoo; Henrik Toft Sørensen; Jiong Li; Onyebuchi A. Arah
doi : 10.2337/dc21-1018
Islet Autoantibody Type-Specific Titer Thresholds Improve Stratification of Risk of Progression to Type 1 Diabetes in Children
Kenney Ng; Harry Stavropoulos; Vibha Anand; Riitta Veijola; Jorma Toppari; Marlena Maziarz; Markus Lundgren; Kathy Waugh; Brigitte I. Frohnert; Frank Martin; William Hagopian; Peter Achenbach; for the T1DI Study Group
doi : 10.2337/dc21-0878
Clinically Relevant Circulating Protein Biomarkers for Type 1 Diabetes: Evidence From a Two-Sample Mendelian Randomization Study
Nahid Yazdanpanah; Mojgan Yazdanpanah; Ye Wang; Vincenzo Forgetta; Michael Pollak; Constantin Polychronakos; J. Brent Richards; Despoina Manousaki
doi : 10.2337/dc21-1049
Remission of Type 2 Diabetes Following a Short-term Intensive Intervention With Insulin Glargine, Sitagliptin, and Metformin: Results of an Open-label Randomized Parallel-Design Trial
Natalia McInnes; Stephanie Hall; Irene Hramiak; Ronald J. Sigal; Ronald Goldenberg; Nikhil Gupta; Remi Rabasa-Lhoret; Manoela Braga; Vincent Woo; Farah Sultan; Rose Otto; Ada Smith; Diana Sherifali; Yan Yun Liu; Hertzel C. Gerstein; on behalf of the REMIT-sita Collaborative Group
doi : 10.2337/dc21-0278
Impact of a Novel Diabetes Support System on a Cohort of Individuals With Type 1 Diabetes Treated With Multiple Daily Injections: A Multicenter Randomized Study
Alessandro Bisio; Stacey Anderson; Lisa Norlander; Grenye O’Malley; Jessica Robic; Selassie Ogyaadu; Liana Hsu; Camilla Levister; Laya Ekhlaspour; David W. Lam; Carol Levy; Bruce Buckingham; Marc D. Breton
doi : 10.2337/dc21-0838
A Randomized Crossover Trial Comparing Glucose Control During Moderate-Intensity, High-Intensity, and Resistance Exercise With Hybrid Closed-Loop Insulin Delivery While Profiling Potential Additional Signals in Adults With Type 1 Diabetes
Barbora Paldus; Dale Morrison; Dessi P. Zaharieva; Melissa H. Lee; Hannah Jones; Varuni Obeyesekere; Jean Lu; Sara Vogrin; André La Gerche; Sybil A. McAuley; Richard J. MacIsaac; Alicia J. Jenkins; Glenn M. Ward; Peter Colman; Carmel E.M. Smart; Rowen Seckold; Bruce R. King; Michael C. Riddell; David N. O’Neal
doi : 10.2337/dc21-1593
Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine
Abhinav Sharma; Yinggan Zheng; Justin A. Ezekowitz; Cynthia M. Westerhout; Jacob A. Udell; Shaun G. Goodman; Paul W. Armstrong; John B. Buse; Jennifer B. Green; Robert G. Josse; Keith D. Kaufman; Darren K. McGuire; Giuseppe Ambrosio; Lee-Ming Chuang; Renato D. Lopes; Eric D. Peterson; Rury R. Holman
doi : 10.2337/dc20-2806
Relationships of Changes in Physical Activity and Sedentary Behavior With Changes in Physical Fitness and Cardiometabolic Risk Profile in Individuals With Type 2 Diabetes: The Italian Diabetes and Exercise Study 2 (IDES_2)
Stefano Balducci; Jonida Haxhi; Massimo Sacchetti; Giorgio Orlando; Patrizia Cardelli; Martina Vitale; Lorenza Mattia; Carla Iacobini; Lucilla Bollanti; Francesco Conti; Silvano Zanuso; Antonio Nicolucci; Giuseppe Pugliese; for the Italian Diabetes and Exercise Study 2 (IDES_2) Investigators
doi : 10.2337/dc21-1505
Body Fat Distribution, Cardiometabolic Traits, and Risk of Major Lower-Extremity Arterial Disease in Postmenopausal Women
Guo-Chong Chen; Rhonda Arthur; Victor Kamensky; Jin Choul Chai; Bing Yu; Aladdin H. Shadyab; Matthew Allison; Yangbo Sun; Nazmus Saquib; Robert A. Wild; Wei Bao; Andrew J. Dannenberg; Thomas E. Rohan; Robert C. Kaplan; Sylvia Wassertheil-Smoller; Qibin Qi
doi : 10.2337/dc21-1565
Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol
Peitao Wu; Jee-Young Moon; Iyas Daghlas; Giulianini Franco; Bianca C. Porneala; Fariba Ahmadizar; Tom G. Richardson; Jonas L. Isaksen; Georgy Hindy; Jie Yao; Colleen M. Sitlani; Laura M. Raffield; Lisa R. Yanek; Mary F. Feitosa; Rafael R.C. Cuadrat; Qibin Qi; M. Arfan Ikram; Christina Ellervik; Ulrika Ericson; Mark O. Goodarzi; Jennifer A. Brody; Leslie Lange; Josep M. Mercader; Dhananjay Vaidya; Ping An; Matthias B. Schulze; Lluis Masana; Mohsen Ghanbari; Morten S. Olesen; Jianwen Cai; Xiuqing Guo; James S. Floyd; Susanne Jäger; Michael A. Province; Rita R. Kalyani; Bruce M. Psaty; Marju Orho-Melander; Paul M. Ridker; Jørgen K. Kanters; Andre Uitterlinden; George Davey Smith; Dipender Gill; Robert C. Kaplan; Maryam Kavousi; Sridharan Raghavan; Daniel I. Chasman; Jerome I. Rotter; James B. Meigs; Jose C. Florez; Josée Dupuis; Ching-Ti Liu; Jordi Merino
doi : 10.2337/dc21-1284
Haptoglobin Phenotype Modifies the Effect of Fenofibrate on Risk of Coronary Event: ACCORD Lipid Trial
Rachel A. Warren; Allie S. Carew; Pantelis Andreou; Christine Herman; Andrew P. Levy; Henry N. Ginsberg; John Sapp; Eric B. Rimm; Susan Kirkland; Leah E. Cahill
doi : 10.2337/dc21-1429
Effect of Loss-of-Function Genetic Variants in PCSK9 on Glycemic Traits, Neurocognitive Impairment, and Hepatobiliary Function
Jonas Ghouse; Gustav Ahlberg; Henning Bundgaard; Morten S. Olesen
doi : 10.2337/dc21-0955
Acute-to-Chronic Glycemic Ratio as a Predictor of COVID-19 Severity and Mortality
Jordi Ramon; Gemma Llauradó; Roberto Güerri; Elisenda Climent; Silvia Ballesta; David Benaiges; Inmaculada López-Montesinos; Humberto Navarro; Natalia Fernández; Maria José Carrera; DÃdac Mauricio; Juana A. Flores-Le Roux; Juan-José Chillarón
doi : 10.2337/dc21-1321
Effect of Fenofibrate Therapy on Laser Treatment for Diabetic Retinopathy: A Meta-Analysis of Randomized Controlled Trials
David Preiss; Enti Spata; Rury R. Holman; Ruth L. Coleman; Laura Lovato; Henry N. Ginsberg; Jane Armitage
doi : 10.2337/dc21-1439
Durability of High-Frequency 10-kHz Spinal Cord Stimulation for Patients With Painful Diabetic Neuropathy Refractory to Conventional Treatments: 12-Month Results From a Randomized Controlled Trial
Erika A. Petersen; Thomas G. Stauss; James A. Scowcroft; Elizabeth S. Brooks; Judith L. White; Shawn M. Sills; Kasra Amirdelfan; Maged N. Guirguis; Jijun Xu; Cong Yu; Ali Nairizi; Denis G. Patterson; Kostandinos C. Tsoulfas; Michael J. Creamer; Vincent Galan; Richard H. Bundschu; Neel D. Mehta; Dawood Sayed; Shivanand P. Lad; David J. DiBenedetto; Khalid A. Sethi; Johnathan H. Goree; Matthew T. Bennett; Nathan J. Harrison; Atef F. Israel; Paul Chang; Paul W. Wu; Charles E. Argoff; Christian E. Nasr; Rod S. Taylor; David L. Caraway; Nagy A. Mekhail
doi : 10.2337/dc21-1813
Comment on Parente et al. The Relationship Between Body Fat Distribution and Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes. Diabetes Care 2021;44:1706–1713
Marieke de Vries; Karin H.A.H. Kaasjager; Harold W. de Valk
doi : 10.2337/dc21-1773
Response to Comment on Parente et al. The Relationship Between Body Fat Distribution and Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes. Diabetes Care 2021;44:1706–1713
Erika B. Parente; Emma H. Dahlström; Valma Harjutsalo; Jussi Inkeri; Stefan Mutter; Carol Forsblom; Niina Sandholm; Daniel Gordin; Per-Henrik Groop; on behalf of the FinnDiane Study Group
doi : 10.2337/dci21-0045
Comment on Shih et al. Increased Incidence of Pediatric Type 1 Diabetes With Novel Association With Coxsackievirus A Species in Young Children but Declined Incidence in Adolescents in Taiwan. Diabetes Care 2021;44:1579–1585
Fu-Shun Yen; James Cheng-Chung Wei
doi : 10.2337/dc21-1398
Response to Comment on Shih et al. Increased Incidence of Pediatric Type 1 Diabetes With Novel Association With Coxsackievirus A Species in Young Children but Declined Incidence in Adolescents in Taiwan. Diabetes Care 2021;44:1579–1585
Wei-Liang Shih; Yi-Ching Tung; Luan-Yin Chang
doi : 10.2337/dci21-0046
Comment on Liu et al. Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017. Diabetes Care 2021;44:2503–2509
Jianping Weng; Zhiguang Zhou; Lixin Guo
doi : 10.2337/dc21-1820
Response to Comment on Liu et al. Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017. Diabetes Care 2021;44:2503–2509
Chang Liu; Jin-Kui Yang
doi : 10.2337/dci21-0047
Comment on Hamblin et al. Capillary Ketone Concentrations at the Time of Colonoscopy: A Cross-Sectional Study With Implications for SGLT2 Inhibitor–Treated Type 2 Diabetes. Diabetes Care 2021;44:e124–e126
Venkatesan Thiruvenkatarajan; Emily J. Meyer; David Jesudason
doi : 10.2337/dc21-1413
Response to Comment on Hamblin et al. Capillary Ketone Concentrations at the Time of Colonoscopy: A Cross-Sectional Study With Implications for SGLT2 Inhibitor–Treated Type 2 Diabetes. Diabetes Care 2021;44:e124–e126
Peter S. Hamblin; Rosemary Wong; Elif I. Ekinci; Shoshana Sztal-Mazer; Shananthan Balachandran; Aviva Frydman; Timothy P. Hanrahan; Raymond Hu; Shara N. Ket; Alan Moss; Mark Ng; Sashikala Ragunathan; Leon A. Bach
doi : 10.2337/dci21-0048
Comment on Stempniewicz et al. Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations. Diabetes Care 2021;44:2000–2009
Jonah Mink; Raj Thakkar; Danielle Jeddah
doi : 10.2337/dc21-2005
