دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
-
http://medilib.ir
- ﻣﺪﺕ ﺯﻣﺎﻥ : 365 ﺭﻭﺯ
قیمت : 3,800,000 تومان- قیمت ویژه : 1,900,000تومان
Cardiopulmonary Resuscitation in the Prone Position in the Operating Room or in the Intensive Care Unit: A Systematic Review
Anez, Cristobal; Becerra-Bola?os, ?ngel; Vives-Lopez, Ariadna; Rodr?guez-Pérez, Aurelio
doi : 10.1213/ANE.0000000000005289
Anesthesia & Analgesia. 132(2):285-292, February 2021.
The prone position is commonly used in certain surgical procedures and to improve oxygenation in mechanically ventilated patients with acute respiratory distress syndrome (ARDS). Cardiorespiratory arrest (CRA) in this position may be more challenging to treat because care providers trained in conventional cardiopulmonary resuscitation (CPR) may not be familiar with CPR in the prone position. The aim of this systematic review is to provide an overview of current evidence regarding the methodology, efficacy, and experience of CPR in the prone position, in patients with the airway already secured. The search strategy included PubMed, Scopus, and Google Scholar. All studies published up to April 2020 including CRA or CPR in the prone position were included. Of the 268 articles located, 52 articles were included: 5 review articles, 8 clinical guidelines in which prone CPR was mentioned, 4 originals, 27 case reports, and 8 editorials or correspondences. Data from reviewed clinical studies confirm that CPR in the prone position is a reasonable alternative to supine CPR when the latter cannot be immediately implemented, and the airway is already secured. Defibrillation in the prone position is also possible. Familiarizing clinicians with CPR and defibrillation in the prone position may improve CPR performance in the prone position.
Basic Science of Frailty—Biological Mechanisms of Age-Related Sarcopenia
Csete, Marie E.
doi : 10.1213/ANE.0000000000005096
Anesthesia & Analgesia. 132(2):293-304, February 2021.
Aging is associated with loss of function across organ systems, contributing to systemic frailty. Loss of skeletal muscle mass and function, in particular, is a major source of frailty in older adults, severely impacting quality of life. Some loss of muscle mass and strength with aging is inevitable, and sarcopenia, the severe loss of muscle mass with aging, is common. Sarcopenia is determined in part by genetics but can be modified by lifestyle choices. The pathophysiologic underpinnings of sarcopenia are complex and multifactorial. In this review, the causes of sarcopenia are surveyed at the systems, cell, subcellular, and molecular levels with emphasis on the interplay between these various causes of this degenerative disease process.
Adult Emergence Agitation: A Veteran-Focused Narrative Review
Tolly, Brian; Waly, Amr; Peterson, Garrett; Erbes, Christopher R.; Prielipp, Richard C.; Apostolidou, Ioanna
doi : 10.1213/ANE.0000000000005211
Anesthesia & Analgesia. 132(2):353-364, February 2021.
Emergence agitation (EA) is a self-limited state of psychomotor excitement during awakening from general anesthesia. EA is confined to the emergence period as consciousness is restored, which sharply distinguishes it from other postoperative delirium states. Sporadic episodes of EA may become violent with the potential for harm to both patients and caregivers, but the long-term consequences of such events are not fully understood. Current literature on EA in adults is limited to small-scale studies with inconsistent nomenclature, variable time periods that define emergence, a host of different surgical populations, and conflicting diagnostic criteria. Therefore, true incidence rates and risk factors are unknown. In adult noncardiac surgery, the incidence of EA is approximately 19%. Limited data suggest that young adults undergoing otolaryngology operations with volatile anesthetic maintenance may be at the highest risk for EA. Currently suggested EA mechanisms are theoretical but might reflect underblunted sympathetic activation in response to various internal (eg, flashbacks or anxiety) or external (eg, surgical pain) stimuli as consciousness returns. Supplemental dexmedetomidine and ketamine may be utilized for EA prevention. Compared to the civilian population, military veterans may be more vulnerable to EA due to high rates of posttraumatic stress disorder (PTSD) manifesting as violent flashbacks; however, confirmatory data are limited. Nonetheless, expert military medical providers suggest that use of patient-centered rapport tactics, PTSD trigger identification and avoidance, and grounding measures may alleviate hyperactive emergence phenomena. Future research is needed to better characterize EA in veterans and validate prophylactic measures to optimize care for these patients. This narrative review provides readers with an important framework to distinguish EA from delirium. Furthermore, we summarize current knowledge of EA risk factors, mechanisms, and adult management strategies and specifically revisit them in the context of veteran perioperative health. The anesthesiology care team is ideally positioned to further explore EA and develop effective prevention and treatment protocols.
Cocaine-Positive Patients Undergoing Elective Surgery: From Avoiding Case Cancellations to Treating Substance Use Disorders
Bartels, Karsten; Schacht, Joseph P.
doi : 10.1213/ANE.0000000000004969
Anesthesia & Analgesia. 132(2):305-307, February 2021.
Perioperative Precedex: Whole New Ball Game or Whole New Ball of Wax?
Grant, Michael C.; Dunn, Lauren K.
doi : 10.1213/ANE.0000000000005158
Anesthesia & Analgesia. 132(2):317-319, February 2021.
Pediatric Acute Kidney Injury After Noncardiac Surgery: Another Vulnerable Population
Atkinson, Douglas B.; DiNardo, James A.
doi : 10.1213/ANE.0000000000005293
Anesthesia & Analgesia. 132(2):329-331, February 2021.
Preoperative Anemia Screening and Treatment: Is It Worth the Return on Investment?
Warner, Matthew A.; Goobie, Susan M.
doi : 10.1213/ANE.0000000000005313
Anesthesia & Analgesia. 132(2):341-343, February 2021.
A Positive Cocaine Urine Toxicology Test and the Effect on Intraoperative Hemodynamics Under General Anesthesia
Moon, Tiffany S.; Pak, Taylor J.; Kim, Agnes; Gonzales, Michael X.; Volnov, Yuri; Wright, Evan; Vu, Kevin Q.; Lu, Rachael D.; Sharifi, Arghavan; Minhajuddin, Abu; Chen, Joy L.; Fox, Pamela E.; Gasanova, Irina; Fox, Amanda A.; Stewart, Jesse; Ogunnaike, Babatunde
doi : 10.1213/ANE.0000000000004808
Anesthesia & Analgesia. 132(2):308-316, February 2021.
Cocaine has a short biological half-life, but inactive urine metabolites may be detectable for a week following use. It is unclear if patients who test positive for cocaine but have a normal electrocardiogram and vital signs have a greater percentage of hemodynamic events intraoperatively.
Effects of an Intraoperative Intravenous Bolus Dose of Dexmedetomidine on Remifentanil-Induced Postinfusion Hyperalgesia in Patients Undergoing Thyroidectomy: A Double-Blind Randomized Controlled Trial
Wu, Zhijie; Yu, Junjie; Lin, Qihua; Li, Huiting; Zhang, Tianhua; Tan, Hongying; Lin, Wenqian; Cao, Longhui
doi : 10.1213/ANE.0000000000005003
Anesthesia & Analgesia. 132(2):320-328, February 2021.
Consecutive exposure to high-dose remifentanil during anesthesia may induce remifentanil-induced postinfusion hyperalgesia (RPH). Dexmedetomidine, a highly selective ?2-adrenergic receptor agonist, may have synergistic effects with opioids and aid in perioperative pain management. In this study, we hypothesized that an intraoperative bolus dose of intravenous dexmedetomidine could alleviate RPH in patients undergoing thyroidectomy under general anesthesia.
Acute Kidney Injury and Outcomes in Children Undergoing Noncardiac Surgery: A Propensity-Matched Analysis
Wingert, Theodora; Grogan, Tristan; Cannesson, Maxime; Sapru, Anil; Ren, Wendy; Hofer, Ira
doi : 10.1213/ANE.0000000000005069
Anesthesia & Analgesia. 132(2):332-340, February 2021.
Acute kidney injury (AKI) has been well documented in adults after noncardiac surgery and demonstrated to be associated with adverse outcomes. We report the prevalence of AKI after pediatric noncardiac surgery, the perioperative factors associated with postoperative AKI, and the association of AKI with postoperative outcomes in children undergoing noncardiac surgery.
Associations of a Preoperative Anemia and Suboptimal Iron Stores Screening and Management Clinic in Colorectal Surgery With Hospital Cost, Reimbursement, and Length of Stay: A Net Cost Analysis
Trentino, Kevin M.; Mace, Hamish; Symons, Kylie; Sanfilippo, Frank M.; Leahy, Michael F.; Farmer, Shannon L.; Watts, Rory D.; Hamdorf, Jeffrey M.; Murray, Kevin
doi : 10.1213/ANE.0000000000005241
Anesthesia & Analgesia. 132(2):344-352, February 2021.
In 2016, a preoperative clinic was implemented to screen, evaluate, and manage anemia and suboptimal iron stores at a major tertiary care medical center in Western Australia. Few studies compare the costs and reimbursements associated with preoperative anemia and suboptimal iron stores management. The objective of our study was to conduct a net cost analysis associated with the implementation of this clinic.
Risk of Hypoxemia by Induction Technique Among Infants and Neonates Undergoing Pyloromyotomy
Park, Raymond S.; Rattana-arpa, Sirirat; Peyton, James M.; Huang, Jia; Kordun, Anna; Cravero, Joseph P.; Zurakowski, David; Kovatsis, Pete G.
doi : 10.1213/ANE.0000000000004344
Anesthesia & Analgesia. 132(2):367-373, February 2021.
In patients presenting for pyloromyotomy, most practitioners prioritize rapid securement of the airway due to concern for aspiration. However, there is a lack of consensus and limited evidence on the choice between rapid sequence induction (RSI) and modified RSI (mRSI).
Logistic Regression in Medical Research
Schober, Patrick; Vetter, Thomas R.
doi : 10.1213/ANE.0000000000005247
Anesthesia & Analgesia. 132(2):365-366, February 2021.
no abstract
Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitor Therapy
Ho, Adrienne K.; Ho, Anthony M.-H.; Cooksley, Tim; Nguyen, Giang; Erb, Jason; Mizubuti, Glenio B.
doi : 10.1213/ANE.0000000000005029
Anesthesia & Analgesia. 132(2):374-383, February 2021.
As part of immune surveillance, killer T lymphocytes search for cancer cells and destroy them. Some cancer cells, however, develop escape mechanisms to evade detection and destruction. One of these mechanisms is the expression of cell surface proteins which allow the cancer cell to bind to proteins on T cells called checkpoints to switch off and effectively evade T-cell–mediated destruction. Immune checkpoint inhibitors (ICIs) are antibodies that block the binding of cancer cell proteins to T-cell checkpoints, preventing the T-cell response from being turned off by cancer cells and enabling killer T cells to attack. In other words, ICIs restore innate antitumor immunity, as opposed to traditional chemotherapies that directly kill cancer cells. Given their relatively excellent risk–benefit ratio when compared to other forms of cancer treatment modalities, ICIs are now becoming ubiquitous and have revolutionized the treatment of many types of cancer. Indeed, the prognosis of some patients is so much improved that the threshold for admission for intensive care should be adjusted accordingly. Nevertheless, by modulating immune checkpoint activity, ICIs can disrupt the intricate homeostasis between inhibition and stimulation of immune response, leading to decreased immune self-tolerance and, ultimately, autoimmune complications. These immune-related adverse events (IRAEs) may virtually affect all body systems. Multiple IRAEs are common and may range from mild to life-threatening. Management requires a multidisciplinary approach and consists mainly of immunosuppression, cessation or postponement of ICI treatment, and supportive therapy, which may require surgical intervention and/or intensive care. We herein review the current literature surrounding IRAEs of interest to anesthesiologists and intensivists. With proper care, fatality (0.3%–1.3%) is rare.
Evaluation and Management of the Physiologically Difficult Airway: Consensus Recommendations From Society for Airway Management
Kornas, Rebecca L.; Owyang, Clark G.; Sakles, John C.; Foley, Lorraine J.; Mosier, Jarrod M.; on behalf of the Society for Airway Management’s Special Projects Committee
doi : 10.1213/ANE.0000000000005233
Anesthesia & Analgesia. 132(2):395-405, February 2021.
Multiple international airway societies have created guidelines for the management of the difficult airway. In critically ill patients, there are physiologic derangements beyond inadequate airway protection or hypoxemia. These risk factors contribute to the “physiologically difficult airway” and are associated with complications including cardiac arrest and death. Importantly, they are largely absent from international guidelines. Thus, we created management recommendations for the physiologically difficult airway to provide practical guidance for intubation in the critically ill. Through multiple rounds of in-person and telephone conferences, a multidisciplinary working group of 12 airway specialists (Society for Airway Management’s Special Projects Committee) over a time period of 3 years (2016–2019) reviewed airway physiology topics in a modified Delphi fashion. Consensus agreement with the following recommendations among working group members was generally high with 80% of statements showing agreement within a 10% range on a sliding scale from 0% to 100%. We limited the scope of this analysis to reflect the resources and systems of care available to out-of-operating room adult airway providers. These recommendations reflect the practical application of physiologic principles to airway management available during the analysis time period.
Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review
Kaski, Shane W.; White, Allison N.; Gross, Joshua D.; Siderovski, David P
doi : 10.1213/ANE.0000000000005309
Anesthesia & Analgesia. 132(2):406-419, February 2021.
A serious adverse effect of prescription opioid analgesics is addiction, both to these analgesics and to illicit drugs like heroin that also activate the µ-opioid receptor (MOR). Opioid use disorder (OUD) and opioid overdose deaths represent a current American health crisis, and the prescription of opioid analgesics has contributed significantly to this crisis. While prescription opioids are highly effective analgesics, there currently exists no facile way to use them for extended periods without the risk of addiction. If addiction caused by MOR-targeting analgesics could be blocked by blending in a new “antiaddiction” ingredient that does not diminish analgesia and does not introduce its own therapeutically limiting side effects, then continued clinical use of prescription opioids for treating pain could be maintained (or even enhanced) instead of curtailed. In this narrative review, we contextualize this hypothesis, first with a brief overview of the current American opioid addiction crisis. The neurobiology of 2 key receptors in OUD development, MOR and the ?-opioid receptor (KOR), is then discussed to highlight the neuroanatomical features and circuitry in which signal transduction from these receptors lie in opposition—creating opportunities for pharmacological intervention in curtailing the addictive potential of MOR agonism. Prior findings with mixed MOR/KOR agonists are considered before exploring new potential avenues such as biased KOR agonists. New preclinical data are highlighted, demonstrating that the G protein–biased KOR agonist nalfurafine reduces the rewarding properties of MOR-targeting analgesics and enhances MOR-targeting analgesic-induced antinociception. Finally, we discuss the recent discovery that a regulator of G protein signaling (namely, RGS12) is a key component of signaling bias at KOR, presenting another drug discovery target toward identifying a single agent or adjuvant to be added to traditional opioid analgesics that could reduce or eliminate the addictive potential of the latter drug.
Early Versus Late Tracheostomy in Patients With Acute Traumatic Spinal Cord Injury: A Systematic Review and Meta-analysis
Mubashir, Talha; Arif, Abdul A.; Ernest, Prince; Maroufy, Vahed; Chaudhry, Rabail; Balogh, Julius; Suen, Colin; Reskallah, Alexander; Williams, George W.
doi : 10.1213/ANE.0000000000005212
Anesthesia & Analgesia. 132(2):384-394, February 2021.
Acute traumatic spinal cord injuries (SCIs) often result in impairments in respiration that may lead to a sequelae of pulmonary dysfunction, increased risk of infection, and death. The optimal timing for tracheostomy in patients with acute SCI is currently unknown. This systematic review and meta-analysis aims to assess the optimal timing of tracheostomy in SCI patients and evaluate the potential benefits of early versus late tracheostomy.
Do Elderly Patients With Diastolic Dysfunction Require Higher Doses of Norepinephrine During General Anesthesia for Noncardiac Surgeries? A Prospective Observational Study
Kahl, Ursula; Vens, Maren; Pollok, Franziska; Menke, Maja; Duckstein, Christoph; Gruetzmacher, Janna; Schirren, Leah; Yu, Yuanyuan; Fischer, Marlene; Z?llner, Christian; Goepfert, Matthias S.; Roeher, Katharina
doi : 10.1213/ANE.0000000000005304
Anesthesia & Analgesia. 132(2):420-429, February 2021.
Diastolic dysfunction is a risk factor for postoperative major cardiovascular events. During anesthesia, patients with diastolic dysfunction might experience impaired hemodynamic function and worsening of diastolic function, which in turn, might be associated with a higher incidence of postoperative complications.
Intraoperative Data Enhance the Detection of High-Risk Acute Kidney Injury Patients When Added to a Baseline Prediction Model
Kim, Minjae; Li, Gen; Mohan, Sumit; Turnbull, Zachary A.; Kiran, Ravi P.; Li, Guohua
doi : 10.1213/ANE.0000000000005057
Anesthesia & Analgesia. 132(2):430-441, February 2021.
Aspects of intraoperative management (eg, hypotension) are associated with acute kidney injury (AKI) in noncardiac surgery patients. However, it is unclear if and how the addition of intraoperative data affects a baseline risk prediction model for postoperative AKI.
Development and Impact of an Institutional Enhanced Recovery Program on Opioid Use, Length of Stay, and Hospital Costs Within an Academic Medical Center: A Cohort Analysis of 7774 Patients
Thiele, Robert H.; Sarosiek, Bethany M.; Modesitt, Susan C.; McMurry, Timothy L.; Tiouririne, Mohamed; Martin, Linda W.; Blank, Randal S.; Shilling, Ashley; Browne, James A.; Bogdonoff, David L.; Bauer, Todd W.; Hedrick, Traci L.
doi : 10.1213/ANE.0000000000005182
Anesthesia & Analgesia. 132(2):442-455, February 2021.
Enhanced Recovery (ER) is a change management framework in which a multidisciplinary team of stakeholders utilizes evidence-based medicine to protocolize all aspects of a surgical care to allow more rapid return of function. While service-specific reports of ER adoption are common, institutional-wide adoption is complex, and reports of institution-wide ER adoption are lacking in the United States. We hypothesized that ER principles were generalizable across an institution and could be implemented across a multitude of surgical disciplines with improvements in length of stay, opioid consumption, and cost of care.
Pharmacokinetics and Pharmacodynamics of 3 Doses of Oral-Mucosal Dexmedetomidine Gel for Sedative Premedication in Women Undergoing Modified Radical Mastectomy for Breast Cancer
Mohamed, Sahar Abdel-Baky; Abdel-Ghaffar, Hala Saad; Hassan, Nivin Abdel-Azim; El Sherif, Fatma Adel; Shouman, Samia Abdelsamie; Omran, Mervat Mostafa; Hassan, Sahar Badr; Allam, Ayat Ahmed Abd EL-Monsef; Sayed, Doaa Gomaa
doi : 10.1213/ANE.0000000000005108
Anesthesia & Analgesia. 132(2):456-464, February 2021.
Buccal dexmedetomidine (DEX) produces adequate preoperative sedation and anxiolysis when used as a premedication. Formulating the drug as a gel decreases oral losses and improves the absorption of buccal DEX. We compared pharmacokinetic and pharmacodynamic properties of 3 doses of buccal DEX gel formulated in our pharmaceutical laboratory for sedative premedication in women undergoing modified radical mastectomy for breast cancer.
Successful Implementation of a Perioperative Data Warehouse Using Another Hospital’s Published Specification From Epic’s Electronic Health Record System
Epstein, Richard H.; Hofer, Ira S.; Salari, Valiollah; Gabel, Eilon
doi : 10.1213/ANE.0000000000004806
Anesthesia & Analgesia. 132(2):465-474, February 2021.
Many hospitals have replaced their legacy anesthesia information management system with an enterprise-wide electronic health record system. Integrating the anesthesia data within the context of the global hospital information infrastructure has created substantive challenges for many organizations. A process to build a perioperative data warehouse from Epic was recently published from the University of California Los Angeles (UCLA), but the generalizability of that process is unknown. We describe the implementation of their process at the University of Miami (UM).
Trends in Comorbidities and Complications Among Patients Undergoing Hip Fracture Repair
Bekeris, Janis; Wilson, Lauren A.; Bekere, Dace; Liu, Jiabin; Poeran, Jashvant; Zubizarreta, Nicole; Fiasconaro, Megan; Memtsoudis, Stavros G.
doi : 10.1213/ANE.0000000000004519
Anesthesia & Analgesia. 132(2):475-484, February 2021.
Hip fracture patients represent various perioperative challenges related to their significant comorbidity burden and the high incidence of morbidity and mortality. As population trend data remain rare, we aimed to investigate nationwide trends in the United States in patient demographics and outcomes in patients after hip fracture repair surgery.
The Effect of Carbetocin Dose on Transmural Dispersion of Myocardial Repolarization in Healthy Parturients Scheduled for Elective Cesarean Delivery Under Spinal Anesthesia: A Prospective, Randomized Clinical Trial
Clunies-Ross, Natasha; Roston, Thomas M.; Taylor, James; Whyte, Simon; Albert, Arianne; G?rges, Matthias; Chau, Anthony
doi : 10.1213/ANE.0000000000004712
Anesthesia & Analgesia. 132(2):485-492, February 2021.
QT interval prolongation is associated with torsade de pointes but remains a poor predictor of drug torsadogenicity. Increased transmural dispersion of myocardial repolarization (TDR), measured as the time interval between the peak and end of the T wave (Tp-e), is a more reliable predictor. Carbetocin is recommended as an uterotonic in patients undergoing cesarean delivery (CD), but its effect on Tp-e is unknown. We evaluated the effect of carbetocin dose on Tp-e and Bazett-corrected QT intervals (QTc) during elective CD under spinal anesthesia.
A Retrospective Study of Neurological Complications in Pediatric Patients With Moyamoya Disease Undergoing General Anesthesia
Lang, Shih-Shan; Vollmer, Emma; Wu, Lezhou; Bathini, Abhijith; Kanuga, Bhavya; Ma, Annie; Barrett, Karyn; Galvez, Jorge A.; Storm, Phillip B.; Huh, Jimmy; Simpao, Allan F
doi : 10.1213/ANE.0000000000004715
Anesthesia & Analgesia. 132(2):493-499, February 2021.
Moyamoya disease is a condition with potentially devastating and permanent neurological sequelae. Adequate volume status and blood pressure, tight control of carbon dioxide to achieve normocarbia, and providing postoperative analgesia to prevent hyperventilation are typical goals that are used during anesthetic care in these patients. The purpose of this study was to assess postanesthesia neurological complications in moyamoya patients undergoing general anesthesia for imaging studies and surgical procedures excluding neurosurgical revascularization.
Influence of Levobupivacaine Regional Scalp Block on Hemodynamic Stability, Intra- and Postoperative Opioid Consumption in Supratentorial Craniotomies: A Randomized Controlled Trial
Carella, Michele; Tran, Gabriel; Bonhomme, Vincent L.; Franssen, Colette
doi : 10.1213/ANE.0000000000005230
Anesthesia & Analgesia. 132(2):500-511, February 2021.
The anesthetic management of supratentorial craniotomy (CR) necessitates tight intraoperative hemodynamic control. This type of surgery may also be associated with substantial postoperative pain. We aimed at evaluating the influence of regional scalp block (SB) on hemodynamic stability during the noxious events of supratentorial craniotomies and total intravenous anesthesia, its influence on intraoperative anesthetic agents’ consumption, and its effect on postoperative pain control.
Exploring Factors Associated With Morbidity and Mortality in Patients With Do-Not-Resuscitate Orders: A National Surgical Quality Improvement Program Database Analysis Within Surgical Groups
Cobert, Julien; Lerebours, Reginald; Peskoe, Sarah B.; Gordee, Alexander; Truong, Tracy; Krishnamoorthy, Vijay; Raghunathan, Karthik; Mureebe, Leila
doi : 10.1213/ANE.0000000000005311
Anesthesia & Analgesia. 132(2):512-523, February 2021.
Anesthesiologists caring for patients with do-not-resuscitate (DNR) orders may have ethical concerns because of their resuscitative wishes and may have clinical concerns because of their known increased risk of morbidity/mortality. Patient heterogeneity and/or emphasis on mortality outcomes make previous studies among patients with DNR orders difficult to interpret. We sought to explore factors associated with morbidity and mortality among patients with DNR orders, which were stratified by surgical subgroups.
Macintosh Videolaryngoscope for Intubation in the Operating Room: A Comparative Quality Improvement Project
De Jong, Audrey; Pouzeratte, Yvan; Laplace, Alexandre; Normanno, Marco; Rollé, Amélie; Verzilli, Daniel; Perrigault, Pierre-François; Colson, Pascal; Capdevila, Xavier; Molinari, Nicolas; Jaber, Samir
doi : 10.1213/ANE.0000000000005031
Anesthesia & Analgesia. 132(2):524-535, February 2021.
“Macintosh”-videolaryngoscopes (VLs) are VLs that allow both direct and indirect laryngoscopy for intubation. We describe the decision-making and implementation-processes that our hospital used regarding the choice of device. We compared the performances of 4 Macintosh-VLs both in direct and indirect laryngoscopy.
Assessment of Anesthesia Capacity in Public Surgical Hospitals in Guatemala
Zha, Yuanting; Truché, Paul; Izquierdo, Erick; Zimmerman, Kathrin; de Izquierdo, Sandra; Lipnick, Michael S.; Law, Tyler J.; Gelb, Adrian W.; Evans, Faye M.
doi : 10.1213/ANE.0000000000005297
Anesthesia & Analgesia. 132(2):536-544, February 2021.
International standards for safe anesthetic care have been developed by the World Federation of Societies of Anaesthesiologists (WFSA) and the World Health Organization (WHO). Whether these standards are met is unknown in many nations, including Guatemala, a country with universal health coverage. We aimed to establish an overview of anesthesia care capacity in public surgical hospitals in Guatemala to help guide public sector health care development.
Using Machine Learning to Evaluate Attending Feedback on Resident Performance
Neves, Sara E.; Chen, Michael J.; Ku, Cindy M.; Karan, Suzanne; DiLorenzo, Amy N.; Schell, Randall M.; Lee, Daniel E.; Diachun, Carol Ann B.; Jones, Stephanie B.; Mitchell, John D.
doi : 10.1213/ANE.0000000000005265
Anesthesia & Analgesia. 132(2):545-555, February 2021.
High-quality and high-utility feedback allows for the development of improvement plans for trainees. The current manual assessment of the quality of this feedback is time consuming and subjective. We propose the use of machine learning to rapidly distinguish the quality of attending feedback on resident performance.
Real-Time Injection Pressure Sensing and Minimal Intensity Stimulation Combination During Ultrasound-Guided Peripheral Nerve Blocks: An Exploratory Observational Trial
Varobieff, Maxime; Choquet, Olivier; Swisser, Fabien; Coudray, Adrien; Menace, Cecilia; Molinari, Nicolas; Bringuier, Sophie; Capdevila, Xavier
doi : 10.1213/ANE.0000000000005308
Anesthesia & Analgesia. 132(2):556-565, February 2021.
Nerve damage can occur after peripheral nerve block (PNB). Ultrasound guidance does not eliminate the risk of intraneural injection or nerve injury. Combining nerve stimulation and injection pressure (IP) monitoring with ultrasound guidance has been suggested to optimize needle tip location in PNB. In this prospective observational study, we hypothesized that measured pairs of IP and minimum intensity of stimulation (MIS) might differentiate successive needle tip locations established by high-resolution ultrasound during PNB.
High-Dose Dabigatran Is an Effective Anticoagulant for Simulated Cardiopulmonary Bypass Using Human Blood
Nadtochiy, Sergiy M.; Baldzizhar, Aksana; Stefanos, Tatsiana; Feng, Changyong; O’Leary, Kade E.; Jones-Smith, Karen L.; Angona, Ronald E.; Eaton, Michael P.
doi : 10.1213/ANE.0000000000005089
Anesthesia & Analgesia. 132(2):566-574, February 2021.
Currently no ideal alternative exists for heparin for cardiopulmonary bypass (CPB). Dabigatran is a direct thrombin inhibitor for which a reversal agent exists. The primary end point of the study was to explore whether Dabigatran was an effective anticoagulant for 120 minutes of simulated CPB.
Anesthetic Potency of Intravenous Infusion of 20% Emulsified Sevoflurane and Effect on the Blood-Gas Partition Coefficient in Dogs
Morohashi, Toru; Itakura, Sayako; Shimokawa, Ken-ichi; Ishii, Fumiyoshi; Sanjo, Yoshimitsu; Kazama, Tomiei
doi : 10.1213/ANE.0000000000005232
Anesthesia & Analgesia. 132(2):575-583, February 2021.
Intravenous (IV) infusions of volatile anesthetics in lipid emulsion may increase blood lipid concentration, potentially altering the anesthetic agent’s blood solubility and blood-gas partition coefficient (BGPC). We examined the influence of a low-lipid concentration 20% sevoflurane emulsion on BGPC, and the anesthetic potency of this emulsion using dogs.
Setting Health-Care Priorities: What Ethical Theories Tell Us
Sookhoo, Nicholas D.; Zhou, Jie
doi : 10.1213/ANE.0000000000005275
Anesthesia & Analgesia. 132(2):e15, February 2021.
Telemedicine in the ICU
Charchaflieh, Jean Gabriel
doi : 10.1213/ANE.0000000000005283
Anesthesia & Analgesia. 132(2):e16, February 2021.
Pocket Anesthesia, 4th ed
Hahn, Robert G.
doi : 10.1213/ANE.0000000000005291
Anesthesia & Analgesia. 132(2):e17, February 2021.
Obstetric Anesthesia: A Case Based and Visual Approach
Kumar, Nishant
doi : 10.1213/ANE.0000000000005310
Anesthesia & Analgesia. 132(2):e18, February 2021.
Chronic Pain Management in General and Hospital Practice
Adams, Meredith C. B.
doi : 10.1213/ANE.0000000000005312
Anesthesia & Analgesia. 132(2):e19, February 2021.
Cricoid Pressure: Do No Harm, But Do It Correctly
Khorasani, Arjang; Salem, M. Ramez; Zeidan, Ahed; Al-Faraj, Ahmed
doi : 10.1213/ANE.0000000000004523
Anesthesia & Analgesia. 132(2):e20-e21, February 2021.
In Response
Zdravkovic, Marko; Rice, Mark J.; Brull, Sorin J.
doi : 10.1213/ANE.0000000000004524
Anesthesia & Analgesia. 132(2):e21-e22, February 2021.
Lack of Evidence for the Benefit of Cricoid Pressure
Priebe, Hans-Joachim
doi : 10.1213/ANE.0000000000004657
Anesthesia & Analgesia. 132(2):e22-e24, February 2021.
In Response
Zdravkovic, Marko; Rice, Mark J.; Brull, Sorin J.
doi : 10.1213/ANE.0000000000004658
Anesthesia & Analgesia. 132(2):e24-e25, February 2021.
Remapping End of Life Discussions
Ballard, Heather A.
doi : 10.1213/ANE.0000000000005277
Anesthesia & Analgesia. 132(2):e25-e26, February 2021.
In Response
Udelsman, Brooks V.; Govea, Nicolas; Cooper, Zara; Chang, David C.; Bader, Angela; Meyer, Matthew J
doi : 10.1213/ANE.0000000000004910
Anesthesia & Analgesia. 132(2):e26-e27, February 2021.
Multimodal Analgesia for Spine Surgery: Does the Intraoperative Opioid Dose Matter?
Forget, Patrice; Cata, Juan P.
doi : 10.1213/ANE.0000000000005006
Anesthesia & Analgesia. 132(2):e27-e28, February 2021.
In Response
Brinck, Elina C. V.; Kontinen, Vesa K.
doi : 10.1213/ANE.0000000000005007
Anesthesia & Analgesia. 132(2):e28-e29, February 2021.
Oral Perphenazine 8 mg: A Low-Cost, Efficacious Antiemetic Option
Williams, Brian A.; Holder-Murray, Jennifer M.; Esper, Stephen A.; Subramaniam, Kathirvel; Skledar, Susan J.; Kentor, Michael L.; Orebaugh, Steven L.; Mangione, Michael P.; Ibinson, James W.; Waters, Jonathan H.; Williams, John P.; Chelly, Jacques E.
doi : 10.1213/ANE.0000000000005279
Anesthesia & Analgesia. 132(2):e29-e31, February 2021.
In Response
Jin, Zhaosheng; Gan, Tong J.; Belani, Kumar G.; Bergese, Sergio; Chung, Frances; Diemunsch, Pierre; Habib, Ashraf S.; Kovac, Anthony L.; Meyer, Tricia A.; Urman, Richard D.; Apfel, Christian C.; Ayad, Sabry; Beagley, Linda; Candiotti, Keith; Englesakis, Marina; Hedrick, Traci L.; Kranke, Peter; Lee, Samuel; Lipman, Daniel; Minkowitz, Harold S.; Morton, John; Philip, Beverly K
doi : 10.1213/ANE.0000000000005280
Anesthesia & Analgesia. 132(2):e31-e33, February 2021.
A New Standard Intubating Position?
Pribonic, Anne P.; Torre, Bryna C.; Cady, Chelsea N.; McHugh, Stephen M.
doi : 10.1213/ANE.0000000000005306
Anesthesia & Analgesia. 132(2):e33, February 2021.
In Response
Tsan, Samuel Ern Hung; Wang, Chew Yin
doi : 10.1213/ANE.0000000000005307
Anesthesia & Analgesia. 132(2):e33-e34, February 2021.
