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It Is Time to Focus on Pustular Psoriasis
Edward W. Cowen, MD, MHSc1
doi : 10.1001/jamadermatol.2021.4634
JAMA Dermatol. 2022;158(1):13-14
Introducing JAMA Network Insights in JAMA Dermatology
John S. Barbieri, MD, MBA1,2; Kanade Shinkai, MD, PhD3,4
doi : 10.1001/jamadermatol.2021.4799
JAMA Dermatol. 2022;158(1):15
The Genomic and Phenotypic Landscape of Ichthyosis
Qisi Sun, MD1; Nareh M. Burgren, MD1; Shayan Cheraghlou, MD2; Amy S. Paller, MD3; Margarita Larralde, MD, PhD4; Lionel Bercovitch, MD5; Jonathan Levinsohn, MD, PhD1; Ivy Ren, BS1; Rong Hua Hu, PhD6; Jing Zhou, PhD6; Theodore Zaki, MD1; Ryan Fan, BA1; Charlie Tian, BA/BS1; Corey Saraceni, MD1; Carol J. Nelson-Williams, BS6; Erin Loring, MS6; Brittany G. Craiglow, MD1; Leonard M. Milstone, MD1; Richard P. Lifton, MD, PhD6,7; Lynn M. Boyden, PhD6; Keith A. Choate, MD, PhD1,6,8
doi : 10.1001/jamadermatol.2021.4242
JAMA Dermatol. 2022;158(1):16-25
Ichthyoses are clinically and genetically heterogeneous disorders characterized by scaly skin. Despite decades of investigation identifying pathogenic variants in more than 50 genes, clear genotype-phenotype associations have been difficult to establish.
Association Between Atopic Dermatitis and Height, Body Mass Index, and Weight in Children
Mathew N. Nicholas, MD1; Charles D. G. Keown-Stoneman, PhD2,3; Jonathon L. Maguire, MD, MSc2,4,5,6; Aaron M. Drucker, MD, ScM1,4,7
doi : 10.1001/jamadermatol.2021.4529
JAMA Dermatol. 2022;158(1):26-32
Atopic dermatitis may be associated with short stature and obesity in children, but most previous studies have been either small or cross-sectional.
Assessing the Potential for Patient-led Surveillance After Treatment of Localized Melanoma (MEL-SELF)
Deonna M. Ackermann, MPH1; Mbathio Dieng, PhD2; Ellie Medcalf, MPH1; Marisa C. Jenkins, MScMed1; Cathelijne H. van Kemenade, MPH1; Monika Janda, PhD3; Robin M. Turner, PhD4; Anne E. Cust, PhD1,5,6; Rachael L. Morton, PhD2; Les Irwig, PhD1; Pascale Guitera, PhD5,7,8; H. Peter Soyer, MD9; Victoria Mar, MD10; Jolyn K. Hersch, PhD1; Donald Low11; Cynthia Low, MLitt11; Robyn P. M. Saw, MS5,12; Richard A. Scolyer, MD5,7,8,13,14; Dorothy Drabarek, MIPH1; David Espinoza, MBiostat2; Anthony Azzi, MD15; Alister M. Lilleyman, MD15; Amelia K. Smit, PhD1,6; Peter Murchie, PhD16; John F. Thompson, MD5,7; Katy J. L. Bell, PhD1
doi : 10.1001/jamadermatol.2021.4704
JAMA Dermatol. 2022;158(1):33-42
Patient-led surveillance is a promising new model of follow-up care following excision of localized melanoma.
Prevalence of Vitiligo Among Adults in the United States
Kavita Gandhi, MS, BSPharm1; Khaled Ezzedine, MD, PhD2; Kathryn P. Anastassopoulos, MS3; Reema Patel, MPH3; Vanja Sikirica, PharmD, MPH1; Shoshana R. Daniel, PhD3; Lynne Napatalung, MD, MA4; Yuji Yamaguchi, MD, PhD5; Rebecca Baik, BS3; Amit G. Pandya, MD6,7
doi : 10.1001/jamadermatol.2021.4724
JAMA Dermatol. 2022;158(1):43-50
Vitiligo can have profound effects on patients and is often associated with other autoimmune comorbid conditions. It is important to understand the current prevalence of vitiligo, including diagnosed, undiagnosed, and subtypes (nonsegmental and segmental).
Sentinel Lymph Node Biopsy Positivity in Patients With Acral Lentiginous and Other Subtypes of Cutaneous Melanoma
Shayan Cheraghlou, MD1; Nelson Ugwu, MD2; Michael Girardi, MD2
doi : 10.1001/jamadermatol.2021.4812
JAMA Dermatol. 2022;158(1):51-58
Acral lentiginous melanoma (ALM) is a rare subtype of malignant melanoma typically occurring on the palmar and plantar surfaces. Although it has distinctive genetic, prognostic, and behavioral characteristics relative to cutaneous melanomas overall, owing to its rarity, treatment is largely guided by data extrapolated from more common subtypes. Although sentinel lymph node (SLN) status has been shown to be a significant prognostic factor for ALM, the independent effect of ALM-subtype disease on the likelihood of SLN positivity and the stage-specific positivity rates for ALM are not well characterized.
Association of Psoriasis With Incident Venous Thromboembolism and Peripheral Vascular Disease
Tai-Li Chen, MD1; Ling-Ling Lee, PhD, RN2; Huei-Kai Huang, MD3,4; Jen-Hung Wang, MSc4; Li-Yu Chen, BA5; Hou-Ren Tsai, MD1; Ching-Hui Loh, MD, PhD6,7; Ching-Chi Chi, MD, MMS, DPhil8,9
doi : 10.1001/jamadermatol.2021.4918
JAMA Dermatol. 2022;158(1):59-67
Psoriasis, venous thromboembolism (VTE), and peripheral vascular disease (PVD) share similar mechanisms involving chronic inflammation. However, the associations between psoriasis and VTE or PVD are unclear.
Evaluation of a Case Series of Patients With Palmoplantar Pustulosis in the United States
Megan H. Noe, MD, MPH, MSCE1; Marilyn T. Wan, MBChB, MPH2; Arash Mostaghimi, MD, MPH, MPA1; Joel M. Gelfand, MD, MSCE3,4; and the Pustular Psoriasis in the US Research Group
doi : 10.1001/jamadermatol.2021.4635
JAMA Dermatol. 2022;158(1):68-72
Palmoplantar pustulosis (PPP) is a is a chronic, orphan disease with limited epidemiological data.
Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States
Megan H. Noe, MD, MPH, MSCE1; Marilyn T. Wan, MBChB, MPH2,3; Arash Mostaghimi, MD, MPH, MPA1,4; Joel M. Gelfand, MD, MSCE2,5; and the Pustular Psoriasis in the US Research Group
doi : 10.1001/jamadermatol.2021.4640
JAMA Dermatol. 2022;158(1):73-78
Generalized pustular psoriasis (GPP) is a chronic, orphan disease with limited epidemiological data.
Physician Perspectives on the Effect of Topical Steroid Costs on Patients and Proposed Solutions
Bina Kassamali, BS1,2; Adam Faletsky, BS1,3; Jane J. Han, BS1,4; Karen Lee, BS1; Christina Lopez, BS1,5; Michelle S. Lee, BA1,2; Lourdes M. Pérez-Chada, MD, MSSc1; Arash Mostaghimi, MD, MPA, MPH1,2,6; Avery Lachance, MD, MPH1,2
doi : 10.1001/jamadermatol.2021.4140
JAMA Dermatol. 2022;158(1):79-83
Rising costs of topical steroids have increased overall health care and patient out-of-pocket costs while increasing administrative burden on dermatologists and office staff.
Evaluation of Site- and Autoantigen-Specific Characteristics of Mucous Membrane Pemphigoid
Nina van Beek, MD1; Khalaf Kridin, MD, PhD2,3; Elena Bühler1; Anne S. Kochan4; Sascha Ständer, MD1; Ralf J. Ludwig, MD2; Detlef Zillikens, MD1; Enno Schmidt, MD, PhD1,2; Claudia Günther, MD4
doi : 10.1001/jamadermatol.2021.4773
JAMA Dermatol. 2022;158(1):84-89
Mucous membrane pemphigoid (MMP) is a rare, heterogeneous subepithelial autoimmune bullous disease. The association between its clinical and immunological features is yet to be fully evaluated.
Checklist for Evaluation of Image-Based Artificial Intelligence Reports in Dermatology
Roxana Daneshjou, MD, PhD1,2; Catarina Barata, PhD3; Brigid Betz-Stablein, PhD4; M. Emre Celebi, PhD5; Noel Codella, PhD6; Marc Combalia, MSc7; Pascale Guitera, MD, PhD8,9; David Gutman, MD, PhD10; Allan Halpern, MD11; Brian Helba, BS12; Harald Kittler, MD13; Kivanc Kose, PhD11; Konstantinos Liopyris, MD, PhD14; Josep Malvehy, MD7; Han Seung Seog, MD, PhD15,16; H. Peter Soyer, MD4; Eric R. Tkaczyk, MD, PhD17,18,19; Philipp Tschandl, MD, PhD13; Veronica Rotemberg, MD, PhD11
doi : 10.1001/jamadermatol.2021.4915
JAMA Dermatol. 2022;158(1):90-96
The use of artificial intelligence (AI) is accelerating in all aspects of medicine and has the potential to transform clinical care and dermatology workflows. However, to develop image-based algorithms for dermatology applications, comprehensive criteria establishing development and performance evaluation standards are required to ensure product fairness, reliability, and safety.
Pseudoxanthoma Elasticum With Cutis Laxa-Like Features
Meredith Gaufin, MD1; Michael A. Cardis, MD1
doi : 10.1001/jamadermatol.2021.4063
JAMA Dermatol. 2022;158(1):99
Pseudoxanthoma Elasticum
Gabrielle Brokamp, BS1; Mari Mori, MD, MS1,2; Esteban Fernandez Faith, MD1,3
doi : 10.1001/jamadermatol.2021.4059
JAMA Dermatol. 2022;158(1):100
Patient-Reported Outcomes in Dermatology
Joslyn S. Kirby, MD, MS, MEd1
doi : 10.1001/jamadermatol.2021.1559
JAMA Dermatol. 2022;158(1):97-98
Arc-Shaped Furrow on the Forehead Extending From Linear Alopecia on the Vertex
Il-Jae Lee, MD1; Seok-Kweon Yun, MD, PhD1,2; Kyung-Hwa Nam, MD, PhD1,2
doi : 10.1001/jamadermatol.2021.4714
JAMA Dermatol. 2022;158(1):101-102
Oral Lichenoid Lesions Associated With Mediastinal Mass and Hypogammaglobulinemia in a Middle-aged Man
Mar Luque-Luna, MD1; Francesc Alamon-Reig, MD1; Pilar Iranzo, MD1
doi : 10.1001/jamadermatol.2021.5087
JAMA Dermatol. 2022;158(1):103-104
Treatment of Cutaneous Squamous Cell Carcinoma With the Topical Histone Deacetylase Inhibitor Remetinostat
James M. Kilgour, MD1; Aatman Shah, MD2; Shaundra Eichstadt, MD3; Irene Bailey, AIBMS1; Sumaira Z. Aasi, MD1; Kavita Y. Sarin, MD, PhD1
doi : 10.1001/jamadermatol.2021.4549
JAMA Dermatol. 2022;158(1):105-107
Treatment of Severe Nail Lichen Planus With Baricitinib
Jöri Pünchera, MD1; Emmanuel Laffitte, MD1
doi : 10.1001/jamadermatol.2021.5082
JAMA Dermatol. 2022;158(1):107-108
