Journal of the American College of Cardiology




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doi : 10.1016/S0735-1097(21)07750-0

Volume 78, Issue 20, 16 November 2021, Page e165

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Contents

doi : 10.1016/S0735-1097(21)07887-6

Volume 78, Issue 20, 16 November 2021, Pages e167-e169

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Diagnostic Performance of Dynamic Myocardial Perfusion Imaging Using Dual-Source Computed Tomography

KakuyaKitagawaMDa?SatoshiNakamuraMDb?HidekiOtaMDcRyoOgawaMDdTakehitoShizukaMDeTadahiroKuboMDfYanYiMDgTatsuroItoMDhNaokiNagasawaRTbTakuOmoriMDiShiroNakamoriMDiTairoKuritaMDiJunSugisawaMDjNaokiHatoriMDeHitoshiNakashimaMDfYiningWangMDgTeruhitoKidoMDdKoukiWatanabeMDkYasuharuMatsumotoMDjlKaoruDohiMDiHajimeSakumaMDm

doi : 10.1016/j.jacc.2021.08.067

Volume 78, Issue 20, 16 November 2021, Pages 1937-1949

Single-center studies indicated a high diagnostic accuracy of dynamic computed tomography perfusion (CTP) imaging in the diagnosis of coronary artery disease (CAD).

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Dynamic Perfusion With CT Angiography: Adding Another Feather to a Heavily Decorated Cap?

GianlucaPontoneMD, PhDaSaimaMushtaqMDaJagatNarulaMD, PhDb

doi : 10.1016/j.jacc.2021.09.016

Volume 78, Issue 20, 16 November 2021, Pages 1950-1953

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Cost-Effectiveness of Lipid-Lowering Treatments in Young Adults

Ciaran N.Kohli-LynchPhDabcBrandon K.BellowsPharmDaYiyiZhangPhDaBonnieSpringPhDdDhruv S.KaziMDeMark J.PletcherMDfEricVittinghoffPhDfNorrina B.AllenPhDdAndrew E.MoranMDa

doi : 10.1016/j.jacc.2021.08.065

Volume 78, Issue 20, 16 November 2021, Pages 1954-1964

Raised low-density lipoprotein cholesterol (LDL-C) in young adulthood (aged 18-39 years) is associated with atherosclerotic cardiovascular disease (ASCVD) later in life. Most young adults with elevated LDL-C do not currently receive lipid-lowering treatment.

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Time to Relax the 40-Year Age Threshold for Pharmacologic Cholesterol Lowering?

Paul A.HeidenreichMD, MSabShoa L.ClarkeMD, PhDbDavid J.MaronMDbc

doi : 10.1016/j.jacc.2021.08.072

Volume 78, Issue 20, 16 November 2021, Pages 1965-1967

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Risk-Benefit of 1-Year DAPT After DES Implantation in Patients Stratified by Bleeding and Ischemic Risk

TullioPalmeriniMDaAntonio GiulioBrunoMDaBjörnRedforsMD, PhDbcdMarcoValgimigliMD, PhDeNevioTaglieriMDaFaustoFeresMDfAlexandreAbizaidMDfRicardoCostaMDfMartineGilardMDgMarie-ClaudeMoriceMDhMyeong-KiHongMD, PhDiByeong-KeukKimMD, PhDiYangsooJangMD, PhDiHyo-SooKimMD, PhDjKyung WooParkMDjAntonioColomboMDkAlaideChieffoMDlMasatoNakamuraMDmLak N.KotinkaduwaPhDbElenaNardiMStatanFrancescoSaiaMD, PhDaMauroGaspariniPhDoGiuliaRizzelloMStatoGioraWeiszMDbcAjay J.KirtaneMD, SMbcRoxanaMehranMDbpBernhardWitzenbichlerMDqNazzarenoGalièMDaGregg W.StoneMDbp

doi : 10.1016/j.jacc.2021.08.070

Volume 78, Issue 20, 16 November 2021, Pages 1968-1986

Although a 1-year duration of dual antiplatelet therapy (DAPT) is used in many patients after drug-eluting stent (DES) implantation, the evidence supporting this duration is uncertain.

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Dual Antiplatelet Duration After DES: Is it Time to Say Goodbye to 1-Year DAPT??

Puja B.ParikhMD, MPH

doi : 10.1016/j.jacc.2021.08.071

Volume 78, Issue 20, 16 November 2021, Pages 1987-1989

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Echocardiographic Ischemic Memory Molecular Imaging for Point-of-Care Detection of Myocardial Ischemia

Brian P.DavidsonMDaJamesHodovanRDCSaMichael E.LayounMDbHarshGolwalaMDaFirasZahrMDaJonathan R.LindnerMDab

doi : 10.1016/j.jacc.2021.08.068

Volume 78, Issue 20, 16 November 2021, Pages 1990-2000

Noninvasive molecular imaging of recent ischemia can potentially be used to diagnose acute coronary syndrome (ACS) with high accuracy.

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The Potential for Retained Microbubbles: To Imaging . . . and Beyond?

Thomas R.PorterMD

doi : 10.1016/j.jacc.2021.08.069

Volume 78, Issue 20, 16 November 2021, Pages 2001-2003

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In-Hospital Initiation of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Reduced Ejection Fraction

Vishal N.RaoMD, MPHabEvanMurrayBScJavedButlerMD, MPH, MBAdLauren B.CooperMD, MHSeZachary L.CoxPharmDfMonaFiuzatPharmDbcJennifer B.GreenMDbgJoAnnLindenfeldMDhDarren K.McGuireMD, MHSciMichael E.NassifMDjCaraO’BrienMDkNehaPagidipatiMD, MPHabKavitaSharmaMDlMuthiahVaduganathanMD, MPHmOrlyVardenyPharmDnGregg C.FonarowMDoRobert J.MentzMDabStephen J.GreeneMDab

doi : 10.1016/j.jacc.2021.08.064

Volume 78, Issue 20, 16 November 2021, Pages 2004-2012

Sodium-glucose cotransporter-2 inhibitor therapy is well suited for initiation during the heart failure hospitalization, owing to clinical benefits that accrue rapidly within days to weeks, a strong safety and tolerability profile, minimal to no effects on blood pressure, and no excess risk of adverse kidney events. There is no evidence to suggest that deferring initiation to the outpatient setting accomplishes anything beneficial. Instead, there is compelling evidence that deferring in-hospital initiation exposes patients to excess risk of early postdischarge clinical worsening and death. Lessons from other heart failure with reduced ejection fraction therapies highlight that deferring initiation of guideline-recommended medications to the U.S. outpatient setting carries a >75% chance they will not be initiated within the next year. Recognizing that 1 in 4 patients hospitalized for worsening heart failure die or are readmitted within 30 days, clinicians should embrace the in-hospital period as an optimal time to initiate sodium-glucose cotransporter-2 inhibitor therapy and treat this population with the urgency it deserves.

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Heart Failure With Reduced Ejection Fraction: “Guideline-Directed Medical Therapy (GDMT)” Versus “The Art of Medicine”

Sheldon H.GottliebMD

doi : 10.1016/j.jacc.2021.09.015

Volume 78, Issue 20, 16 November 2021, Pages 2013-2016

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Aldo R. Castañeda, MD, PhD, In Memoriam: Reflections on a Mentor and Program Leader

John E.MayerJr.MD

doi : 10.1016/j.jacc.2021.10.005

Volume 78, Issue 20, 16 November 2021, Pages 2017-2018

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The Fifth-Generation Cardiac Troponin T and Cardiovascular Disease in the Community

YasuyukiHondaMDYejinMokPhD, MPHJunichiIshigamiMD, PhD, MPHKellan E.AshleyMDRon C.HoogeveenPhDChristie M.BallantyneMDAmy B.KargerMD, PhDDavidCouperPhDElizabethSelvinPhD, MPHKunihiroMatsushitaMD, PhD

doi : 10.1016/j.jacc.2021.08.066

Volume 78, Issue 20, 16 November 2021, Pages 2019-2021

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Does Repeat Revascularization Introduce Bias for Reducing Mortality in the Antiplatelet Therapy Group?

WenhuiLiMPharmHanxuZhangPhDQianXiangPhDYiminCuiMD, PhD

doi : 10.1016/j.jacc.2021.08.063

Volume 78, Issue 20, 16 November 2021, Page e171

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Reply: Does Repeat Revascularization Introduce Bias for Reducing Mortality in the Antiplatelet Therapy Group?

HideyukiKawashimaMDPatrick W.SerruysMD, PhDRutaoWangMDMattiaLunardiMDYoshinobuOnumaMD, PhDSYNTAX Extended Survival Investigators

doi : 10.1016/j.jacc.2021.09.012

Volume 78, Issue 20, 16 November 2021, Pages e173-e174

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Correction

doi : 10.1016/j.jacc.2021.09.014

Volume 78, Issue 20, 16 November 2021, Page 2022

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