Journal of the American College of Cardiology




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doi : 10.1016/S0735-1097(21)06228-8

Volume 78, Issue 17, 26 October 2021, Page e131

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Contents

doi : 10.1016/S0735-1097(21)06230-6

Volume 78, Issue 17, 26 October 2021, Pages e133-e135

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Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study

Nathan K.ItogaMDab?Daniel S.TawfikMDc?Maria E.Montez-RathPhDdTara I.ChangMD, MSd

doi : 10.1016/j.jacc.2021.08.035

Volume 78, Issue 17, 26 October 2021, Pages 1671-1678

SBP and DBP have important associations with cardiovascular events, but are seldom considered simultaneously.

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Optimal BP Targets to Prevent Stroke and MI: Is There a Lesser of 2 Evils??

Franz H.MesserliMDaEvgeniya V.ShalaevaMDbEmrushRexhajMDc

doi : 10.1016/j.jacc.2021.09.013

Volume 78, Issue 17, 26 October 2021, Pages 1679-1681

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Association of Genetic Variants With Outcomes in Patients With Nonischemic Dilated Cardiomyopathy

LuisEscobar-LopezMDabc?Juan PabloOchoaMD, PhDabcd?Jesús G.MirelisMD, PhDabcMaría ÁngelesEspinosaMDbeMarinaNavarroMDbcfMaríaGallego-DelgadoMD, PhDbgRobertoBarriales-VillaMD, PhDbhAinhoaRobles-MezcuaMDbiMaría TeresaBasurte-ElorzMDjLauraGutiérrez García-MorenoMDbkVicenteClimentMDlJuanJiménez-JaimezMD, PhDmMaría VictoriaMogollón-JiménezMDnJavierLopezMD, PhDboMaría LuisaPeña-PeñaMDpAnaGarcía-ÁlvarezMD, PhDbdqMaríaBrionPhDbrTomasRipoll-VeraMD, PhDs…PabloGarcia-PaviaMD, PhDabcdz

doi : 10.1016/j.jacc.2021.08.039

Volume 78, Issue 17, 26 October 2021, Pages 1682-1699

The clinical relevance of genetic variants in nonischemic dilated cardiomyopathy (DCM) is unsettled.

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The Evolving Science of Dilated Cardiomyopathy?

Ray E.HershbergerMD

doi : 10.1016/j.jacc.2021.08.038

Volume 78, Issue 17, 26 October 2021, Pages 1700-1702

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Improving Longitudinal Outcomes, Efficiency, and Equity in the Care of Patients With Congenital Heart Disease

Brett R.AndersonMD, MBA, MSaKacieDraganMPHbSarahCrookPhDaJoyce L.WooMD, MScStephenCookMDdEdward L.HannanPhDeJane W.NewburgerMD, MPHfMarshallJacobsMDgEmile A.BachaMDhRobertVincentMDiKhanhNguyenMDjKathleenWalsh-SpoonhowerMDkRalphMoscaMDlNeilDevejianMDmSteven A.KamenirMDnGeorge M.AlfierisMDopMichael F.SwartzPhDoDavidMeyerMD, MSqrErin A.PaulMDsJohnBillingsJDbon behalf of the

doi : 10.1016/j.jacc.2021.08.040

Volume 78, Issue 17, 26 October 2021, Pages 1703-1713

Longitudinal follow-up, resource utilization, and health disparities are top congenital heart research and care priorities. Medicaid claims include longitudinal data on inpatient, outpatient, emergency, pharmacy, rehabilitation, home health utilization, and social determinants of health—including mother-infant pairs.

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The Value of Longitudinal Follow-Up and Linked Registries?

Jeffrey P.JacobsMDaDavid M.OvermanMDbJames S.TweddellMDc

doi : 10.1016/j.jacc.2021.08.041

Volume 78, Issue 17, 26 October 2021, Pages 1714-1716

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Burnout and Well-Being Among Cardiology Fellowship Program Directors

Michael W.CullenMDaJulie B.DampMDbVictorSoukoulisMD, PHDcFriederike K.KeatingMDdIslamAbudayyehMD, MPHeAlexAuseonDOfDeepakBhaktaMD, MBAgAtifQasimMDhAudreySeryakMD, MBAiSakima A.SmithMD, MPHjMarty C.TamMDkPaulTheriotlGabyWeissmanMDm

doi : 10.1016/j.jacc.2021.08.034

Volume 78, Issue 17, 26 October 2021, Pages 1717-1726

The third annual Cardiovascular Diseases (CV) Fellowship Program Directors (PDs) Survey sought to understand burnout and well-being among CV fellowship PDs.

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Cardiology Fellowship Program Director Wellness: The Future Depends on it?

Jeffrey T.KuvinMDaJonathanHalperinMDb

doi : 10.1016/j.jacc.2021.08.033

Volume 78, Issue 17, 26 October 2021, Pages 1727-1729

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Modulation of Cardiac Arrhythmogenesis by Epicardial Adipose Tissue: JACC State-of-the-Art Review

Auriane C.ErnaultMScabVeronique M.F.MeijborgPhDaRubenCoronelMD, PhDac

doi : 10.1016/j.jacc.2021.08.037

Volume 78, Issue 17, 26 October 2021, Pages 1730-1745

Obesity is a significant risk factor for arrhythmic cardiovascular death. Interactions between epicardial adipose tissue (EAT) and myocytes are thought to play a key role in the development of arrhythmias. In this review, the authors investigate the influence of EAT on arrhythmogenesis. First, they summarize electrocardiographic evidence showing the association between increased EAT volume and atrial and ventricular conduction delay. Second, they detail the structural cross talk between EAT and the heart and its arrhythmogenicity. Adipose tissue infiltration within the myocardium constitutes an anatomical obstacle to cardiac excitation. It causes activation delay and increases the risk of arrhythmias. Intercellular electrical coupling between cardiomyocytes and EAT can further slow conduction and increase the risk of block, favoring re-entry and arrhythmias. Finally, EAT secretes multiple substances that influence cardiomyocyte electrophysiology either by modulating ion currents and electrical coupling or by stimulating fibrosis. Thus, structural and paracrine cross talk between EAT and cardiomyocytes facilitates arrhythmias.

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Perspectives of Racially and Ethnically Diverse U.S. Cardiologists: Insights From the ACC Professional Life Survey

Kevin L.ThomasMDaLaxmi S.MehtaMDbAnne K.RzeszutMAcSandra J.LewisMDdClaire S.DuvernoyMDePamela S.DouglasMDaACC Diversity & Inclusion Task Force and ACC Women in Cardiology Section

doi : 10.1016/j.jacc.2021.09.002

Volume 78, Issue 17, 26 October 2021, Pages 1746-1750

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Early Impedance-Guided Intervention Improves Long-Term Outcome in Patients With Heart Failure

MichaelKleiner ShochatMD, PhDMaratFudimMD, MHSDanielKapustinBScMarkKazatskerMDIliaKleinerMDJean MarcWeinsteinMBBSGurusherPanjrathMDGuyRozenMD, MHAArielRoguinMD, PhDSimcha R.MeiselMD, MSc

doi : 10.1016/j.jacc.2021.08.036

Volume 78, Issue 17, 26 October 2021, Pages 1751-1752

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When Will We Stop Debating on the Value of TEE in CABG?

YongZhanMDEthan Y.BrovmanMDFrederickCobeyMD, MPH

doi : 10.1016/j.jacc.2021.08.031

Volume 78, Issue 17, 26 October 2021, Page e137

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Reply: When Will We Stop Debating on the Value of TEE in CABG?

Thomas S.MetkusMDMichael C.GrantMDBrittanyZwischenbergerMDRobertHigginsMD

doi : 10.1016/j.jacc.2021.08.032

Volume 78, Issue 17, 26 October 2021, Pages e139-e140

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