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Transition to a fully online journal
Rowan H Harwood
doi : 10.1093/ageing/afab202
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1863–1864
Tobacco smoking and older people amid the COVID-19 pandemic: an elephant in the room
Yao Yao, Keyang Liu, Junfeng Zhang, Hiroyasu Iso, Tai Hing Lam
doi : 10.1093/ageing/afab170
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1865–1867
Enhanced lateral flow testing strategies in care homes are associated with poor adherence and were insufficient to prevent COVID-19 outbreaks: results from a mixed methods implementation study
John S P Tulloch, Massimo Micocci, Peter Buckle, Karen Lawrenson, Patrick Kierkegaard, Anna McLister, Adam L Gordon, Marta García-Fiñana, Steve Peddie, Matthew Ashton, Iain Buchan, Paula Parvulescu
doi : 10.1093/ageing/afab162
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1868–1875
Care homes have been severely affected by the SARS-CoV-2 pandemic. Rapid antigen testing could identify most SARS-CoV-2 infected staff and visitors before they enter homes. We explored implementation of staff and visitor testing protocols using lateral flow devices (LFDs).
Impact of COVID-19 restrictions on carers of persons with dementia in the UK: a qualitative study
Vimal Sriram, Crispin Jenkinson, Michele Peters
doi : 10.1093/ageing/afab156
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1876–1885
informal carers provide the majority of the support for persons with dementia living at home. Restrictions imposed due to COVID-19 have had a profound impact on the daily life of the entire population. This study provides insight into the impact of these restrictions on carers of people with dementia living at home.
Platypnoea-orthodeoxia syndrome in an older patient with COVID-19 pneumonia and orthostatic hypotension—a case of prolonged hospital admission
Muhammad Azam Ismail, Katie Trevest
doi : 10.1093/ageing/afab166
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1886–1887
An 89-year-old woman was admitted to hospital with a fall, general malaise and low oxygen saturations. She tested positive for SARS-CoV-2 and commenced on standard therapy for COVID-19 pneumonia. She improved initially but reported ongoing dyspnoea exacerbated by position. Following investigations to rule out other causes, she was given a diagnosis of platypnoea-orthodeoxia syndrome (POS). She was treated with gradual verticalization therapy with supplemental oxygen and subsequently discharged to an intermediate care bed (ICB).
Spontaneous psoas haematoma from enhanced venous thromboembolism (VTE) prophylaxis for COVID-19 infection
Abhay Kumar Das, Toby Price, Joshua Woodcock-Shaw, Ngoni Khomisani Zava
doi : 10.1093/ageing/afab181
Age and Ageing, Volume 50, Issue 6, November 2021, Page 1888
Shake, rattle and get moving again
Clemens Becker
doi : 10.1093/ageing/afab187
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1889–1890
Atrial fibrillation and cognitive decline: it takes more than an irregular heart beat, to beat the brain
Dimitrios Sagris, Gregory Y H Lip
doi : 10.1093/ageing/afab158
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1891–1893
Advance care planning for emergencies in care homes: meaningful conversations and trusting relationships matter
Anne Finucane, Bruce Mason, Kirsty Boyd
doi : 10.1093/ageing/afab159
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1894–1895
Managing older people with diabetes—we need better evidence with wise interpretation!
Alan J Sinclair
doi : 10.1093/ageing/afab165
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1896–1898
Aducanumab and the certainty of evidence
Jenny McCleery, Terence J Quinn
doi : 10.1093/ageing/afab167
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1899–1900
Supporting stroke survivors living in care homes: challenges and opportunities for practice development and research
Jennifer Kirsty Burton, Marion F Walker
doi : 10.1093/ageing/afab180
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1901–1903
Diagnosing sarcopenia: turn your eyes back on patients
Alfonso J Cruz-Jentoft
doi : 10.1093/ageing/afab184
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1904–1905
How do we define and measure sarcopenia? A meta-analysis of observational studies
Paulo R Carvalho do Nascimento, Martin Bilodeau, Stéphane Poitras
doi : 10.1093/ageing/afab148
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1906–1913
Effects of gait adaptability training on falls and fall-related fractures in older adults: a systematic review and meta-analysis
Jens Eg Nørgaard, Martin Gronbech Jorgensen, Jesper Ryg, Jane Andreasen, Mathias Brix Danielsen, Daniel Kjærgaard Steiner, Stig Andersen
doi : 10.1093/ageing/afab105
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1914–1924
falls among older adults are common and can have devastating consequences. A novel task-specific exercise modality, gait adaptability training (GAT), has shown promising preventive effects. This systematic review and meta-analysis synthesise the evidence regarding GATs effect on falls and fall-related fractures in community-dwelling older adults.
Perceptions and experiences of residents and relatives of emergencies in care homes: a systematic review and metasynthesis of qualitative research
Ffion Curtis, Withanage Iresha Udayangani Jayawickrama, Despina Laparidou, Dedunu Weligamage, Weerapperuma Kankanamge Wijaya Sarathchandra Kumarawansha, Marishona Ortega, Aloysius Niroshan Siriwardena
doi : 10.1093/ageing/afab182
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1925–1934
the perceptions and experiences of care home residents and their families are important for understanding and improving the quality of emergency care.
Individualisation of glycaemic management in older people with type 2 diabetes: a systematic review of clinical practice guidelines recommendations
Antoine Christiaens, Séverine Henrard, Lorène Zerah, Olivia Dalleur, Isabelle Bourdel-Marchasson, Benoit Boland
doi : 10.1093/ageing/afab157
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1935–1942
Recommendations for individualised glycaemic management in older people with type 2 diabetes (T2D) have recently been provided in clinical practice guidelines (CPGs) issued by major scientific societies. The aim of this systematic review is to compare the content of these recommendations concerning health assessment, targets for glycaemic control, lifestyle management and glucose-lowering therapy across CPGs.
Depressive symptom heterogeneity among older adults after hip fracture
Jennifer M Kirk, Jay Magaziner, Michelle D Shardell, Alice S Ryan, Ann L Gruber-Baldini, Denise Orwig, Marc C Hochberg, Alan M Rathbun
doi : 10.1093/ageing/afab168
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1943–1951
to evaluate patterns of depressive symptoms after hip fracture and examine their impact on functional recovery.
Age and clinical outcomes after hip fracture surgery: do octogenarian, nonagenarian and centenarian classifications matter?
Takahisa Ogawa, Haggai Schermann, Hiroki Kobayashi, Kiyohide Fushimi, Atsushi Okawa, Tetsuya Jinno
doi : 10.1093/ageing/afab137
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1952–1960
older patients with hip fractures are arbitrarily classified as octogenarians, nonagenarians and centenarians. We have designed this study to quantify in-hospital mortality and complications among each of these groups. We hypothesised that the associations between age and in-hospital mortality and complications are continuously increasing, and that these risks increase rapidly when patients reach a certain age.
Orthopaedic physiotherapists’ perceptions of mechanisms for observed variation in the implementation of physiotherapy practices in the early postoperative phase after hip fracture: a UK qualitative study
Brittannia Volkmer, Euan Sadler, Kate Lambe, Finbarr C Martin, Salma Ayis, Lauren Beaupre, Ian D Cameron, Celia L Gregson, Antony Johansen, Morten Tange Kristensen, Jay Magaziner, Catherine Sackley, Toby O Smith, Boris Sobolev, Katie J Sheehan
doi : 10.1093/ageing/afab131
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1961–1970
to explore physiotherapists’ perceptions of mechanisms to explain observed variation in early postoperative practice after hip fracture surgery demonstrated in a national audit.
Association of plasma FGF21 levels with muscle mass and muscle strength in a national multicentre cohort study: Korean Frailty and Aging Cohort Study
Eun Roh, Soon Young Hwang, Hye Jin Yoo, Sei Hyun Baik, Belong Cho, Yong Soon Park, Hyeon Ju Kim, Sam-Gyu Lee, Bong Jo Kim, Hak Chul Jang, Miji Kim, Chang Won Won, Kyung Mook Choi
doi : 10.1093/ageing/afab178
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1971–1978
despite of the beneficial effects of fibroblast growth factor (FGF) 21 in several metabolic diseases, the association of plasma FGF21 with muscle mass and muscle strength is still unclear.
Associations between inflammation, cardiovascular biomarkers and incident frailty: the British Regional Heart Study
Douglas G J McKechnie, A Olia Papacosta, Lucy T Lennon, Sheena E Ramsay, Peter H Whincup, S Goya Wannamethee
doi : 10.1093/ageing/afab143
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1979–1987
cardiovascular disease (CVD) and chronic inflammation are implicated in the development of frailty. Longitudinal analyses of inflammatory markers, biomarkers of cardiac dysfunction and incidence of frailty are limited.
Barriers and potential solutions in the recruitment and retention of older patients in clinical trials—lessons learned from six large multicentre randomized controlled trials
Thomas Buttgereit, Andriko Palmowski, Noah Forsat, Maarten Boers, Miles D Witham, Nicolas Rodondi, Elisavet Moutzouri, Antonio Jesus Quesada Navidad, Arnoud W J van’t Hof, Bart van der Worp, Laura Coll-Planas, Marieke Voshaar, Maarten de Wit, José da Silva, Sven Stegemann, Johannes W Bijlsma, Marcus Koeller, Simon Mooijaart, Patricia M Kearney, Frank Buttgereit
doi : 10.1093/ageing/afab147
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1988–1996
older people remain underrepresented in clinical trials, and evidence generated in younger populations cannot always be generalized to older patients.
Dutch emergency physicians insufficiently educated in geriatric emergency medicine: results of a nationwide survey
Özcan Sir, Gijs Hesselink, Yvonne Schoon, Marcel G M Olde Rikkert
doi : 10.1093/ageing/afab175
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 1997–2003
Emergency physicians (EPs) provide care to older adults with complex health problems. Treating these patients is challenging for many EPs, which might originate from modest geriatric education.
Patients’ preferred place of death: patients are willing to consider their preferences, but someone has to ask them
Iris van Doorne, Marjon van Rijn, Sjoerd M Dofferhoff, Dick L Willems, Bianca M Buurman
doi : 10.1093/ageing/afab176
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2004–2011
end-of-life care is not always in line with end-of-life preferences, so patients do not always die at their preferred place of death (PPD). This study aims to identify factors associated with patients’ PPD and changes in PPD.
Preferred life expectancy and the association with hypothetical adverse life scenarios among Norwegians aged 60+
Vegard Skirbekk, Ellen Melbye Langballe, Bjørn Heine Strand
doi : 10.1093/ageing/afab113
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2012–2018
how long older individuals prefer to live given hypothetical adverse changes in health and living conditions has been insufficiently studied.
Why is living alone in older age related to increased mortality risk? A longitudinal cohort study
Jessica G Abell, Andrew Steptoe
doi : 10.1093/ageing/afab155
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2019–2024
Living alone has been associated with increased mortality risk, but it is unclear whether this is a result of a selection effect or the impact of stressful life changes such as widowhood or divorce leading to changes in living arrangements. We therefore examined the association between living alone, transitions in living arrangements and all-cause mortality.
The frequency and impact of undiagnosed benign paroxysmal positional vertigo in outpatients with high falls risk
Lyndon J Hawke, Christopher J Barr, James V McLoughlin
doi : 10.1093/ageing/afab122
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2025–2030
The frequency and impact of undiagnosed benign paroxysmal positional vertigo (BPPV) in people identified with high falls risk has not been investigated.
Activities of daily living (ADL) and instrumental activities of daily living (IADL) disability in Swedish 85-year-olds born three decades apart—findings from the H70 study
Hanna Falk Erhag, Hanna Wetterberg, Lena Johansson, Lina Rydén, Ingmar Skoog
doi : 10.1093/ageing/afab112
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2031–2037
Older adults make up the fastest growing segment of the population, and disability rates increase with age. There is much debate whether later born cohorts of 85-year-olds will face the same disability rates as earlier born cohorts. This study aimed to examine ADL and IADL disability in three birth cohorts of Swedish 85-year-olds born three decades apart, examined in 1986–87, 2008–10 and 2015-16, as well as potential factors associated with ADL and IADL disability in these birth-cohorts.
Physical multimorbidity and incident urinary incontinence among community-dwelling adults aged ?50 years: findings from a prospective analysis of the Irish Longitudinal Study on Ageing
Lee Smith, Jae Il Shin, Ramy Abou Ghayda, Adonis Hijaz, David Sheyn, Rachel Pope, Sun Hwi Hong, Sung Eun Kim, Petre Cristian Ilie, Anne Marie Carrie, Simona Ippoliti, Pinar Soysal, Yvonne Barnett, Damiano Pizzol, Ai Koyanagi
doi : 10.1093/ageing/afab151
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2038–2046
There are no prospective studies on the association between multimorbidity and urinary incontinence (UI), while mediators in this association are unknown. Thus, we aimed to (i) investigate the longitudinal association between multimorbidity and UI in a large sample of Irish adults aged ?50 years and (ii) investigate to what extent physical activity, polypharmacy, cognitive function, sleep problems, handgrip strength and disability mediate the association.
Life satisfaction among older adults with impairment in activities of daily living
Dominic E Boccaccio, Irena Cenzer, Kenneth E Covinsky
doi : 10.1093/ageing/afab172
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2047–2054
Many older adults experience decline in function, but maintain high levels of life satisfaction. The factors associated with high life satisfaction among those with functional impairment are not well understood.
The impact of additional payments on functional decline among long-term care health facility residents in Japan
Xueying Jin, Nanako Tamiya, Kazuaki Uda, Hideo Yasunaga
doi : 10.1093/ageing/afab121
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2055–2062
Additional payment approach has been one of the most important incentives in long-term care (LTC) systems for the past 20 years in Japan.
An intervention to increase physical activity in care home residents: results of a cluster-randomised, controlled feasibility trial (the REACH trial)
Anne Forster, Jennifer Airlie, Alison Ellwood, Mary Godfrey, John Green, Bonnie Cundill, Bryony Dawkins, Nicola McMaster, Claire Hulme, Robert Cicero, Vicki McLellan, Liz Graham, Bev Gallagher, David R Ellard, Joan Firth, Amanda Farrin, the REACH Programme Team
doi : 10.1093/ageing/afab130
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2063–2078
Care home (CH) residents are mainly inactive, leading to increased dependency and low mood. Strategies to improve activity are required.
Survival and outcomes for stroke survivors living in care homes: a prospective cohort study
Amanda Clery, Finbarr C Martin, Patrick Redmond, Iain Marshall, Christopher McKevitt, Catherine Sackley, Jill Manthorpe, Charles Wolfe, Yanzhong Wang
doi : 10.1093/ageing/afab140
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2079–2087
Stroke survivors living in care homes require high levels of support with everyday living. The aims of this study were to describe the survival, health status and care received by stroke survivors living in care homes at 1-year post-stroke, compared with those in their own homes.
Frequent and severe hypoglycaemia detected with continuous glucose monitoring in older institutionalised patients with diabetes
Benjamin Bouillet, Pauline Tscherter, Laurence Vaillard, Christine Nonciaux, Philippe Hourdain, Anne Ravier, Alexia Rouland, Jean Michel Petit, Bruno Vergès, Emilienne Quilot
doi : 10.1093/ageing/afab128
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2088–2093
Little is known about the prevalence of hypoglycaemia in older people with diabetes. However, the HbA1c goal is ?8% for institutionalised patients with treatments that can cause hypoglycaemia.
All-cause mortality, cardiovascular mortality, major cardiovascular events and hypoglycaemia of patients with diabetes onset at an older age: results from the 10-year nationwide cohort study
Ming-Yueh Chou, Shih-Tsung Huang, Chih-Kuang Liang, Li-Ning Peng, Yu-Te Lin, Fei-Yuan Hsiao, Liang-Kung Chen
doi : 10.1093/ageing/afab183
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2094–2104
Longitudinal adverse outcomes are unclear among adults with diabetes according to the age of onset.
The nurse-coordinated cardiac care bridge transitional care programme: a randomised clinical trial
Patricia Jepma, Lotte Verweij, Bianca M Buurman, Michel S Terbraak, Sara Daliri, Corine H M Latour, Gerben ter Riet, Fatma Karapinar - Çarkit, Jill Dekker, Jose L Klunder, Su-San Liem, Arno H M Moons, Ron J G Peters, Wilma J M Scholte op Reimer
doi : 10.1093/ageing/afab146
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2105–2115
after hospitalisation for cardiac disease, older patients are at high risk of readmission and death.
Total cost of care increases significantly from early to mild Alzheimer’s disease: 5-year ALSOVA follow-up
Viivi Jetsonen, Virpi Kuvaja-Köllner, Tarja Välimäki, Tuomas Selander, Janne Martikainen, Anne M Koivisto
doi : 10.1093/ageing/afab144
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2116–2122
We studied the costs of formal and informal care in relation to Alzheimer’s disease (AD) progression.
Reduced Clostridioides difficile infections in hospitalised older people through multiple quality improvement strategies
Carla Maria Dohrendorf, Steffen Unkel, Simone Scheithauer, Martin Kaase, Volker Meier, Diana Fenz, Jürgen Sasse, Manfred Wappler, Jutta Schweer-Herzig, Tim Friede, Utz Reichard, Helmut Eiffert, Roland Nau, Jana Seele
doi : 10.1093/ageing/afab169
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2123–2132
To reduce infections with Clostridioides difficile (CDI) in geriatric patients by interventions easily implementable in standard clinical care.
Relationship between Fried’s frailty phenotype and oral frailty in long-term care residents
Kaija Hiltunen, Riitta K T Saarela, Hannu Kautiainen, Hanna-Maria Roitto, Kaisu H Pitkälä, Päivi Mäntylä
doi : 10.1093/ageing/afab177
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2133–2139
oral frailty (OFr) may be called a syndrome lacking a consensus on its definition.
Acute sarcopenia changes following hospitalization: influence of pre-admission care dependency level
Anton De Spiegeleer, Hasan Kahya, Dolores Sanchez-Rodriguez, Karolina Piotrowicz, Murielle Surquin, Ester Marco, Celine Detremerie, Dhurgham Hussein, Suzy Hope, Dhayana Dallmeier, Genia Decker, Dana Hrnciarikova, Joanna Czesak, Miguel Toscano-Rico, Delky Meza-Valderrama, Gülistan Bahat, Amélie Descamps, Evelien Wynendaele, Dirk Elewaut, Hana Vankova, Francesco Landi, Florence Benoit, Jerzy Gasowski, Nele Van Den Noortgate
doi : 10.1093/ageing/afab163
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2140–2146
Hospitalization is associated with acute changes in sarcopenia status in older people, but the influencing factors are not fully understood. Pre-admission care dependency level as a risk factor has not yet been investigated.
Sarcopenia is associated with 3-month and 1-year mortality in geriatric rehabilitation inpatients: RESORT
Jane Xu, Esmee M Reijnierse, Jacob Pacifico, Ching S Wan, Andrea B Maier
doi : 10.1093/ageing/afab134
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2147–2156
Sarcopenia is highly prevalent in geriatric rehabilitation patients and can worsen prognosis. This study aimed to investigate the association of sarcopenia and components of sarcopenia with 3-month and 1-year post-discharge mortality in geriatric rehabilitation inpatients.
Long-term effect of a 24-week multicomponent intervention on physical performance and frailty in community-dwelling older adults
Gahee Oh, Heayon Lee, Chan Mi Park, Hee-Won Jung, Eunju Lee, Il-Young Jang, Jack M Guralnik, Dae Hyun Kim
doi : 10.1093/ageing/afab149
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2157–2166
Multicomponent interventions improve physical function and frailty in older adults, but their long-term benefit remains uncertain.
Developing and evaluating a frailty index for older South Africans—findings from the HAALSI study
Fred J Barker, Justine I Davies, F Xavier Gomez-Olive, Kathleen Kahn, Fiona E Matthews, Collin F Payne, Joshua A Salomon, Stephen M Tollman, Alisha N Wade, Richard W Walker, Miles D Witham
doi : 10.1093/ageing/afab111
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2167–2173
despite rapid population ageing, few studies have investigated frailty in older people in sub-Saharan Africa. We tested a cumulative deficit frailty index in a population of older people from rural South Africa.
Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?
Ge Bai, Agnieszka Szwajda, Yunzhang Wang, Xia Li, Hannah Bower, Ida K Karlsson, Boo Johansson, Anna K Dahl Aslan, Nancy L Pedersen, Sara Hägg, Juulia Jylhävä
doi : 10.1093/ageing/afab106
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2174–2182
frailty shows an upward trajectory with age, and higher levels increase the risk of mortality. However, it is less known whether the shape of frailty trajectories differs by age at death or whether the rate of change in frailty is associated with mortality.
Multimorbidity patterns and risk of frailty in older community-dwelling adults: a population-based cohort study
Clare Tazzeo, Debora Rizzuto, Amaia Calderón-Larrañaga, Albert Roso-Llorach, Alessandra Marengoni, Anna-Karin Welmer, Graziano Onder, Caterina Trevisan, Davide Liborio Vetrano
doi : 10.1093/ageing/afab138
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2183–2191
the aim of this study was to examine the cross-sectional and longitudinal associations of different multimorbidity patterns with physical frailty in older adults.
Global cognitive performance at 4-year follow-up in individuals with atrial fibrillation—findings from The Irish Longitudinal Study on Ageing
Triona McNicholas, Katy Tobin, Susan O’Callaghan, Rose Anne Kenny
doi : 10.1093/ageing/afab141
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2192–2198
Atrial fibrillation (AF) has been proposed as a risk factor for cognitive impairment, even in the absence of a history of stroke. This study investigates whether AF is associated with increased risk of cognitive decline in a community-dwelling population of adults over the age of 50.
Longitudinal associations between C-reactive protein and cognitive performance in normative cognitive ageing and dementia
Nathan A Lewis, Jamie E Knight
doi : 10.1093/ageing/afab152
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2199–2205
systemic inflammation appears to play an important role in the pathogenesis and expression of Alzheimer’s disease and other dementias. Previous research has found that elevated levels of serum C-reactive protein (CRP) is associated with poorer cognitive functioning and increased risk for dementia. However, most studies are limited by single CRP measurements, which fail to capture long-term inflammatory exposures or dynamic changes in inflammation and cognition which may occur across repeated measurements.
What gets recorded, counts: dementia recording in primary care compared with a specialist database
Katrina A S Davis, Christoph Mueller, Mark Ashworth, Matthew Broadbent, Amelia Jewel, Mariam Molokhia, Gayan Perera, Robert J Stewart
doi : 10.1093/ageing/afab164
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2206–2213
databases of electronic health records are powerful tools for dementia research, but data can be influenced by incomplete recording. We examined whether people with dementia recorded in a specialist database (from a mental health and dementia care service) differ from those recorded in primary care.
Creation and validation of a polysocial score for mortality among community-dwelling older adults in the USA: the health and retirement study
Yongjing Ping, Michelle C Oddén, Robert S Stawski, Hoda S Abdel Magid, Chenkai Wu
doi : 10.1093/ageing/afab174
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2214–2221
the interrelatedness between social determinants of health impedes researchers to identify important social factors for health investment. A new approach is needed to quantify the aggregate effect of social factors and develop person- centred social interventions.
Long-term conditions, multimorbidity, lifestyle factors and change in grip strength over 9 years of follow-up: Findings from 44,315 UK biobank participants
Christopher Hurst, James C Murray, Antoneta Granic, Susan J Hillman, Rachel Cooper, Avan Aihie Sayer, Sian M Robinson, Richard M Dodds
doi : 10.1093/ageing/afab195
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2222–2229
Weak grip strength is associated with a range of adverse health outcomes and an accelerated decline in grip strength confers an even greater risk. The factors associated with change in grip strength in mid-life remain to be fully determined.
Implementing post-diagnostic support for people living with dementia in England: a qualitative study of barriers and strategies used to address these in practice
Alison Wheatley, Claire Bamford, Greta Brunskill, Laura Booi, Karen Harrison Dening, Louise Robinson on behalf of the PriDem study team
doi : 10.1093/ageing/afab114
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2230–2237
inequalities and gaps in post-diagnostic support (PDS) for people with dementia persist despite a policy focus on dementia in England and Wales. Understanding and overcoming the factors contributing to these inequalities is vital to improve care for people living with dementia (PLWD) and their families.
Understanding the experience of living well, beyond the age of 85 years: a qualitative analysis using themes from a meta-ethnography
Francine Toye, Cathy Jenkins, Karen Barker
doi : 10.1093/ageing/afab179
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2238–2245
Increase in life-expectancy is not necessarily matched by an increase in quality of life.
A realist evaluation of loneliness interventions for older people
Alice Day, Kay Phelps, John Maltby, Emma Palmer, Keith Snell, Derek Raine, Simon Conroy
doi : 10.1093/ageing/afab188
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2246–2253
the aim of this study was to develop a programme theory to inform the design of loneliness interventions and guide any future evaluations.
Preventing depression in older people with multimorbidity: 24-month follow-up of a trial of internet-delivered cognitive behaviour therapy
Jennifer R Read, Louise Sharpe, Amy L Burton, Patricia A Areán, Patrick J Raue, Sarah McDonald, Nickolai Titov, Milena Gandy, Blake F Dear
doi : 10.1093/ageing/afab145
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2254–2258
older people coping with the impacts of living with multimorbidity are at increased risk of developing a depressive disorder.
Feasibility of remote Memory Clinics using the plan, do, study, act (PDSA) cycle
Jemima T Collins, Biju Mohamed, Antony Bayer
doi : 10.1093/ageing/afab173
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2259–2263
A timely diagnosis of dementia is crucial for initiating and maintaining support for people living with dementia. The coronavirus disease (COVID) pandemic temporarily halted Memory Clinics, where this is organised, and rate of dementia diagnosis has fallen. Despite increasing use of alternatives to face-to-face (F2F) consultations in other departments, it is unclear whether this is feasible within the traditional Memory Clinic model.
‘What matters to you?’ Health outcome prioritisation in treatment decision-making for older patients
Suzanne Festen, Yvette Z van Twisk, Barbara C van Munster, Pauline de Graeff
doi : 10.1093/ageing/afab160
Age and Ageing, Volume 50, Issue 6, November 2021, Pages 2264–2269
for shared decision-making, it is important to discuss of the patients’ priorities in order to align treatment decisions with these priorities.
Syphilis has no age limit
Clarisse Marcombes, Barbara Papouin, Nicolas Ortonne, Charlotte Wemmert, Anne Sophie Lascaux, Saskia Ingen-Housz-Oro, Charlotte Bernigaud
doi : 10.1093/ageing/afab161
Age and Ageing, Volume 50, Issue 6, November 2021, Page 2270
Perspectives on hypertension treatment in older persons
David J Stott, William B Applegate
doi : 10.1093/ageing/afy055
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e1–e2
Computerised prescribing support still needs a human touch
Charlotte Quintens, Greet Van de Sijpe, Lorenz Van der Linden, Isabel Spriet
doi : 10.1093/ageing/afaa200
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e3–e4
Risk from low blood pressure in frail older adults: diastolic pressure and pulse pressure are important
J David Spence
doi : 10.1093/ageing/afaa084
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e5–e6
Reply to ‘Seasonal ambient changes influence inpatient falls’ Magota et al.
P J López-Soto, M H Smolensky, L L Sackett-Lundeen, L M A Rodríguez-Borrego
doi : 10.1093/ageing/afx156
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e7–e8
Mary Godfrey 1953–2020
Anne Forster, John Young
doi : 10.1093/ageing/afaa291
Age and Ageing, Volume 50, Issue 6, November 2021, Page e9
Corrigendum to: Prevention of adverse drug reactions in hospitalized older patients with multi-morbidity and polypharmacy: the SENATOR* randomized controlled clinical trial
Denis O'Mahony, Adalsteinn Gudmundsson, Roy L Soiza, Mirko Petrovic, Alfonso Jose Cruz-Jentoft, Antonio Cherubini, Richard Fordham, Stephen Byrne, Darren Dahly, Paul Gallagher, Amanda Lavan, Denis Curtin, Kieran Dalton, Shane Cullinan, Evelyn Flanagan, Frances Shiely, Olafur Samuelsson, Astros Sverrisdottir, Selvarani Subbarayan, Lore Vandaele, Eline Meireson, Beatriz Montero-Errasquin, Aurora Rexach-Cano, Andrea Correa Perez, Isabel Lozano-Montoya, Manuel Vélez-Díaz-Pallarés, Annarita Cerenzia, Samanta Corradi, Maria Soledad Cotorruelo Ferreiro, Federica Dimitri, Paolo Marinelli, Gaia Martelli, Rebekah Fong Soe Khioe, Joseph Eustace
doi : 10.1093/ageing/afab120
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e10–e11
Corrigendum to: The role of illness acuity on the association between frailty and mortality in emergency department patients referred to internal medicine
Mohammad Habibullah Pulok, Olga Theou, Alexandra M van der Valk, Kenneth Rockwood
doi : 10.1093/ageing/afaa153
Age and Ageing, Volume 50, Issue 6, November 2021, Page e12
A Hospital Wide Point Prevalence of Adult Urinary Incontinence and Audit of Continence Care
Patricia Harkins, Helen O'Brien, Deirdre McCartan, Nizrull Nasir, Billy Twomey, Karthika Srikumar, Tara Coughlan, Sean Kennelly, Paul McElwaine, Desmond O'Neill, Dan Ryan, Collins Ronan
doi : 10.1093/ageing/afy222
Age and Ageing, Volume 50, Issue 6, November 2021, Page e13
Changes in time spent walking and the risk of incident dementia in older Japanese people: the Ohsaki Cohort 2006 Study
Yasutake Tomata, Shu Zhang, Kemmyo Sugiyama, Yu Kaiho, Yumi Sugawara, Ichiro Tsuji
doi : 10.1093/ageing/afy066
Age and Ageing, Volume 50, Issue 6, November 2021, Page e14
Systematic reviews: guidance relevant for studies of older people
Susan D Shenkin, Jennifer K Harrison, Tim Wilkinson, Richard M Dodds, John P A Ioannidis
doi : 10.1093/ageing/afx185
Age and Ageing, Volume 50, Issue 6, November 2021, Page e15
Erratum to: Diagnostic accuracy of dementia screening tools in the Chinese population: a systematic review and meta-analysis of 167 diagnostic studies
Zhaohua Huo, Jiaer Lin, Baker K K Bat, Joyce Y C Chan, Kelvin K F Tsoi, Benjamin H K Yip
doi : 10.1093/ageing/afab190
Age and Ageing, Volume 50, Issue 6, November 2021, Page e16
Erratum to: The Pathfields Tool: a frailty case-finding tool using primary care IT—implications for population health management
David Attwood, James Boorer, Wendy Ellis, Michelle Earley, Jillian Denovan, Agnies Calkoen, Gerard Hart, Maria Williams, Nicholas Burdett, Mel Lemon, Suzy Hope, Julia Chisnell
doi : 10.1093/ageing/afaa181
Age and Ageing, Volume 50, Issue 6, November 2021, Pages e17–e18
Drug consumption and futile medication prescribing in the last year of life: an observational study
D Curtin, D O'mahony, P Gallagher
doi : 10.1093/ageing/afy084
Age and Ageing, Volume 50, Issue 6, November 2021, Page e19
Retracted: Effect of immobilization on vitamin D status and bone mass in chronically hospitalized disabled stroke patients
Sato Yoshihiro, Kuno Haruko, Asoh Takeshi, Honda Yoshiaki, Oizumi Kotaro
doi : 10.1093/ageing/afz156
Age and Ageing, Volume 50, Issue 6, November 2021, Page e20
