American Journal of Respiratory and Critical Care Medicine




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سفارش

Reconstructing Phenotypes in Recurrent Severe Wheeze in Young Children

Jonathan M. Gaffin

doi : 10.1164/rccm.202105-1294ED

Volume 204, Issue 5, pp. 495–496

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Place Matters: Residential Racial Segregation and Chronic Obstructive Pulmonary Disease

John R. Balmes

doi : 10.1164/rccm.202105-1209ED

Volume 204, Issue 5, pp. 496–498

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Bacterial Coinfection in COVID-19 and Influenza Pneumonia

Daniel M. Musher

doi : 10.1164/rccm.202106-1467ED

Volume 204, Issue 5, pp. 498–500

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Identifying Survivors of Sepsis at Risk for Adverse Cardiovascular Outcomes

Florian B. Mayr 1,2 and Hallie C. Prescott 3,4

doi : 10.1164/rccm.202105-1322ED

Volume 204, Issue 5, pp. 500–501

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The Conundrum of Pain, Opiate Use, and Delirium: Analgosedation or Analgesia-First Approach?

Christina J. Hayhurst 1,2, Christopher G. Hughes 1,2, and Pratik P. Pandharipande 1,2

doi : 10.1164/rccm.202104-0968ED

Volume 204, Issue 5, pp. 502–503

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Atrial Fibrillation, Obstructive Sleep Apnea, and Continuous Positive Airway Pressure: No Easy Fix

Matthew Hind 1,2 and Tom Wong 3

doi : 10.1164/rccm.202105-1208ED

Volume 204, Issue 5, pp. 503–505

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A Ginger Root or Plum Model for the Tuberculosis “Granuloma”?

Véronique Dartois 1,2 and Thomas Dick 1,2,3

doi : 10.1164/rccm.202104-1052ED

Volume 204, Issue 5, pp. 505–507

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Ensuring Access to Albuterol in Schools: From Policy to Implementation. An Official ATS/AANMA/ALA/NASN Policy Statement

Anna Volerman , Ashley A. Lowe , Andrea A. Pappalardo , Charmayne M. C. Anderson , Kathryn V. Blake , Tyra Bryant-Stephens , Thomas Carr , Heather Carter , Lisa Cicutto , Joe K. Gerald , Tina Miller , Nuala S. Moore , Hanna Phan , S. Christy Sadreameli , Andrea Tanner , Tonya A. Winders , and Lynn B. Gerald ; on behalf of the American Thoracic Society Assembly on Behavioral Science and Health Services Research

doi : 10.1164/rccm.202106-1550ST

Volume 204, Issue 5, pp. 508–522

For children with asthma, access to quick-relief medications is critical to minimizing morbidity and mortality. An innovative and practical approach to ensure access at school is to maintain a supply of stock albuterol that can be used by any student who experiences respiratory distress. To make this possible, state laws allowing for stock albuterol are needed to improve medication access.

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Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes

Polly F. M. Robinson 1,2*, Sara Fontanella 1*, Sachin Ananth 1,2, Aldara Martin Alonso 1, James Cook 1,2, Daphne Kaya-de Vries 1,2, Luisa Polo Silveira 1,2, Lisa Gregory 1, Clare Lloyd 1, Louise Fleming 1,2, Andrew Bush 1,2, Adnan Custovic 1‡§, and Sejal Saglani 1,2‡

doi : 10.1164/rccm.202009-3696OC

Volume 204, Issue 5, pp. 523–535

Preschool wheezing is heterogeneous, but the underlying mechanisms are poorly understood.

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Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease

Han Woo 1, Emily P. Brigham 1, Kassandra Allbright 1, Chinedu Ejike 1, Panagis Galiatsatos 1, Miranda R. Jones 2, Gabriela R. Oates 3, Jerry A. Krishnan 4*, Christopher B. Cooper 5,6, Richard E. Kanner 7, Russell P. Bowler 8, Eric A. Hoffman 9, Alejandro P. Comellas 9, Gerard Criner 10*, R. Graham Barr 11, Fernando J. Martinez 12*, MeiLan Han 13*, Victor E. Ortega 14, Trisha M. Parekh 15, Stephanie Christenson 16, Daniel Belz 1, Sarath Raju 1, Amanda Gassett 17,18,19, Laura M. Paulin 20, Nirupama Putcha 1, Joel D. Kaufman 17,18,19, and Nadia N. Hansel 1

doi : 10.1164/rccm.202009-3721OC

Volume 204, Issue 5, pp. 536–545

Racial residential segregation has been associated with worse health outcomes, but the link with chronic obstructive pulmonary disease (COPD) morbidity has not been established.

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Early Bacterial Identification among Intubated Patients with COVID-19 or Influenza Pneumonia: A European Multicenter Comparative Clinical Trial

Anahita Rouzé 1,2, Ignacio Martin-Loeches 3,4,5, Pedro Povoa 6,7,8, Matthieu Metzelard 9, Damien Du Cheyron 10, Fabien Lambiotte 11, Fabienne Tamion 12, Marie Labruyere 13, Claire Boulle Geronimi 14, Ania Nieszkowska 15, Martine Nyunga 16, Olivier Pouly 17, Arnaud W. Thille 18, Bruno Megarbane 19, Anastasia Saade 20, Emili Diaz 21, Eleni Magira 22, Jean-François Llitjos 23, Catia Cilloniz 24, Iliana Ioannidou 25, Alexandre Pierre 26, Jean Reignier 27, Denis Garot 28, Louis Kreitmann 29, Jean-Luc Baudel 30, Muriel Fartoukh 31, Gaëtan Plantefeve 32, Alexandra Beurton 33,34, Pierre Asfar 35, Alexandre Boyer 36, Armand Mekontso-Dessap 37, Demosthenes Makris 38, Christophe Vinsonneau 39, Pierre-Edouard Floch 40, Nicolas Weiss 41,42, Adrian Ceccato 43, Antonio Artigas 44, Mathilde Bouchereau 1, Alain Duhamel 45,46, Julien Labreuche 45,46, and Saad Nseir 1,2; for the coVAPid Study Group

doi : 10.1164/rccm.202101-0030OC

Volume 204, Issue 5, pp. 546–556

Early empirical antimicrobial treatment is frequently prescribed to critically ill patients with coronavirus disease (COVID-19) based on Surviving Sepsis Campaign guidelines.

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Association between Troponin I Levels during Sepsis and Postsepsis Cardiovascular Complications

Michael A. Garcia 1*, Justin M. Rucci 1*, Khanh K. Thai 2, Yun Lu 2, Patricia Kipnis 2, Alan S. Go 2, Manisha Desai 3,4, Nicholas A. Bosch 1, Adriana Martinez 2, Heather Clancy 2, Ycar Devis 1, Laura C. Myers 2, Vincent X. Liu 2, and Allan J. Walkey 1

doi : 10.1164/rccm.202103-0613OC

Volume 204, Issue 5, pp. 557–565

Sepsis commonly results in elevated serum troponin levels and increased risk for postsepsis cardiovascular complications; however, the association between troponin levels during sepsis and cardiovascular complications after sepsis is unclear.

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Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain

Matthew S. Duprey 1, Sandra M. A. Dijkstra-Kersten 2,3, Irene J. Zaal 2,3, Becky A. Briesacher 1, Jane S. Saczynski 1, John L. Griffith 4, John W. Devlin 1,5, and Arjen J. C. Slooter 2,3,6

doi : 10.1164/rccm.202010-3794OC

Volume 204, Issue 5, pp. 566–572

It is unclear whether opioid use increases the risk of ICU delirium. Prior studies have not accounted for confounding, including daily severity of illness, pain, and competing events that may preclude delirium detection.

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Effect of Continuous Positive Airway Pressure on Arrhythmia in Atrial Fibrillation and Sleep Apnea: A Randomized Controlled Trial

Gunn Marit Traaen 1,2,3, Lars Aakerøy 4,5, Tove-Elizabeth Hunt 1,2,6, Britt Øverland 7, Christina Bendz 1, Lars Øivind Sande 8, Svend Aakhus 9,10, Morten Wang Fagerland 11, Sigurd Steinshamn 4,5, Ole-Gunnar Anfinsen 1,6, Richard John Massey 1,2, Kaspar Broch 1,3, Thor Ueland 12, Harriet Akre 2,13, Jan Pål Loennechen 5,10, and Lars Gullestad 1,2,3

doi : 10.1164/rccm.202011-4133OC

Volume 204, Issue 5, pp. 573–582

Sleep apnea (SA) is highly prevalent in patients with atrial fibrillation (AF), and both conditions are associated with adverse cardiovascular outcomes.

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Micro–Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology

Gordon Wells 1, Joel N. Glasgow 2, Kievershen Nargan 1, Kapongo Lumamba 1, Rajhmun Madansein 3, Kameel Maharaj 3, Robert L. Hunter 4, Threnesan Naidoo 5, Llelani Coetzer 6, Stephan le Roux 6, Anton du Plessis 6, and Adrie J. C. Steyn 1,2,7

doi : 10.1164/rccm.202101-0032OC

Volume 204, Issue 5, pp. 583–595

Our current understanding of tuberculosis (TB) pathophysiology is limited by a reliance on animal models, the paucity of human TB lung tissue, and traditional histopathological analysis, a destructive two-dimensional approach that provides limited spatial insight. Determining the three-dimensional (3D) structure of the necrotic granuloma, a characteristic feature of TB, will more accurately inform preventive TB strategies.

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Novelties in Lung Cancer Screening

Vicky Mai 1,2, Nicholas Quigley 1, Pascalin Roy 1, and Catherine Labbé 1,3

doi : 10.1164/rccm.202012-4505RR

Volume 204, Issue 5, pp. 596–598

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Evaluation of Droplet Countermeasures by a Particle Visualization System in Simulated Bronchoscopy

Kei Morikawa , Hirotaka Kida , Hiroshi Handa , Takeo Inoue , and Masamichi Mineshita

doi : 10.1164/rccm.202009-3430IM

Volume 204, Issue 5, pp. 599–602

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Development of a Mask for Bronchoscopy to Prevent Infection during the COVID-19 Pandemic: Image Evaluation

Hirotoshi Yasui 1, Shotaro Okachi 1, Noriaki Fukatsu 2, and Kazuhide Sato 1,2,3,4,5

doi : 10.1164/rccm.202010-4037IM

Volume 204, Issue 5, pp. e56–e58

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New Guideline Diagnosis of Fibrotic Hypersensitivity Pneumonitis in Idiopathic Pulmonary Fibrosis

Reoto Takei 1, Yasuhiko Yamano 1, Kensuke Kataoka 1, Toshiki Yokoyama 1, Toshiaki Matsuda 1, Tomoki Kimura 1, Mutsumi Ozasa 2, Junya Fukuoka 2, Takeshi Johkoh 3, and Yasuhiro Kondoh 1*

doi : 10.1164/rccm.202102-0407LE

Volume 204, Issue 5, pp. 603–605

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Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis

Paul McNally 1,2*, Daryl Butler 1,2, Yuliya V. Karpievitch 3,4, Barry Linnane 1,5, Sarath Ranganathan 6,7,8, Stephen M. Stick 3,4,9, Graham L. Hall 4,10, and André Schultz 3,4,9; on behalf of SHIELD CF and AREST CF

doi : 10.1164/rccm.202012-4332LE

Volume 204, Issue 5, pp. 605–608

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Reduced Proportion and Activity of Natural Killer Cells in the Lung of Patients with Idiopathic Pulmonary Fibrosis

Tamara Cruz 1*, Minxue Jia 1,2*, John Sembrat 1, Tracy Tabib 1, Naomi Agostino 1, Tullia C. Bruno 1, Dario Vignali 1, Pablo Sanchez 1, Robert Lafyatis 1, Ana L. Mora 1, Panayiotis Benos 1,2, and  Mauricio Rojas 1‡

doi : 10.1164/rccm.202012-4418LE

Volume 204, Issue 5, pp. 608–610

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Opioids for Sedation: Has the Pendulum Swung Too Far?

Brian P. Murray 1* and Andrea Sikora Newsome 2,3

doi : 10.1164/rccm.202104-1012LE

Volume 204, Issue 5, pp. 611

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Reply to Murray and Newsome

Matthew S. Duprey 1, Arjen J. C. Slooter 2,3, and John W. Devlin 4,5*

doi : 10.1164/rccm.202105-1085LE

Volume 204, Issue 5, pp. 612

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No Strong Evidence for Ruling Out the Role of Coagulation in Long-Term Disability after Critical Illness

Taro Yasuma 1, Corina N. D’Alessandro-Gabazza 1, Osamu Hataji 2, Tetsu Kobayashi 1, and Esteban C. Gabazza 1*,

doi : 10.1164/rccm.202104-0980LE

Volume 204, Issue 5, pp. 613

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Reply to Yasuma et al.

Nathan E. Brummel 1,2, Lorraine B. Ware 4,2, and Timothy D. Girard 3,2*; on behalf of all the authors

doi : 10.1164/rccm.202105-1133LE

Volume 204, Issue 5, pp. 613–614

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Neighborhoods with 25% Minority Residents Are Still Mostly White

Andrew R. Spector 1* and Onyinye I. Iweala 2

doi : 10.1164/rccm.202103-0810LE

Volume 204, Issue 5, pp. 614–615

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Reply to Spector and Iweala

Priya V. Borker 1*, Emely Carmona 1, Utibe R. Essien 1, Gul Jana Saeed 1, S. Mehdi Nouraie 1, Jessie P. Bakker 2, Christy J. Stitt 2, Mark S. Aloia 2, and Sanjay R. Patel 1

doi : 10.1164/rccm.202104-1030LE

Volume 204, Issue 5, pp. 615–616

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Erratum: Patient-centered Outcomes Research in Interstitial Lung Disease: An Official American Thoracic Society Research Statement

doi : 10.1164/rccm.v204erratum1a

Volume 204, Issue 5, pp. 616

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Inhaled Marijuana and the Lungs

Sarah Neff , Matthew G. Drake , Christopher G. Slatore , and Ellen Burnham

doi : 10.1164/rccm.2044P9

Volume 204, Issue 5, pp. P9–P10

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