Journal of the American College of Cardiology




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doi : 10.1016/S0735-1097(21)05733-8

Volume 78, Issue 9, 31 August 2021, Page e49

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Contents

doi : 10.1016/S0735-1097(21)05735-1

Volume 78, Issue 9, 31 August 2021, Pages e51-e54

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Colchicine in Patients With Chronic Coronary Disease in Relation to Prior Acute Coronary Syndrome

Tjerk S.J.OpstalMDabAernoud T.L.FioletMDcdAmbervan BroekhovenMDaArendMosterdMD, PhDdeJohn W.EikelboomMD, PhDfStefan M.NidorfMD, PhDghPeter L.ThompsonMD, PhDgijMichielDuyvendakPharmD, PhDklJ.W. Martijnvan EckMD, PhDmEugène A.van BeekMD, PhDnFrankden HartogMD, PhDoCharley A.BudgeonPhDjWillem A.BaxMD, PhDpJan G.P.TijssenPhDqrSalouaEl MessaoudiMD, PhDaJan H.CornelMD, PhDabd

doi : 10.1016/j.jacc.2021.06.037

Volume 78, Issue 9, 31 August 2021, Pages 859-866

Colchicine reduces risk of cardiovascular events in patients post–myocardial infarction and in patients with chronic coronary disease. It remains unclear whether this effect is related to the time of onset of treatment following an acute coronary syndrome (ACS).

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Low-Dose Colchicine for the Management of Coronary Artery Disease?

Jean-ClaudeTardifMDGuillaumeMarquis-GravelMD, MSc

doi : 10.1016/j.jacc.2021.07.002

Volume 78, Issue 9, 31 August 2021, Pages 867-869

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Pregnancy-Related Aortic Complications in Women With Marfan Syndrome

NupoorNarulaMDRichard B.DevereuxMDGrace P.MalongaMPHIngridHriljacMDMary J.RomanMD

doi : 10.1016/j.jacc.2021.06.034

Volume 78, Issue 9, 31 August 2021, Pages 870-879

The risk of pregnancy-associated vascular complications in Marfan syndrome (MFS) is uncertain because of ascertainment bias, prepartum lack of knowledge of diagnosis, and insufficient peripartum imaging data. Furthermore, U.S. and European guidelines differ in pregnancy recommendations in MFS.

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Further Evidence for the Safety Considerations in Pregnancy of Women With Marfan Syndrome?

Melissa L.RussoMDaAnji T.YetmanMDb

doi : 10.1016/j.jacc.2021.07.010

Volume 78, Issue 9, 31 August 2021, Pages 880-882

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Contemporary Left Ventricular Assist Device Outcomes in an Aging Population: An STS INTERMACS Analysis

DominicEmersonMDaJoannaChikweMDaPedroCatarinoMDaMohamedHassaneinMD, PhDaLuqinDengPhDbRyan S.CantorPhDbAmyRoachMDaRobertColeMDaFardadEsmailianMDaJonKobashigawaMDaJaimeMoriguchiMDaJames K.KirklinMDb

doi : 10.1016/j.jacc.2021.06.035

Volume 78, Issue 9, 31 August 2021, Pages 883-894

Survival, functional outcomes, and quality of life after left ventricular assist device (LVAD) are ill-defined in elderly patients, and with new-generation devices.

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Is Durable Left Ventricular Assist Device Therapy a Viable Option for the Elderly??

Francis D.PaganiMD, PhD

doi : 10.1016/j.jacc.2021.07.001

Volume 78, Issue 9, 31 August 2021, Pages 895-897

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Gender Differences in the Pursuit of Cardiac Electrophysiology Training in North America

NashwaAbdulsalamMBBChabAnne M.GillisMDcAnne K.RzeszutMAdCelina M.YongMD, MBA, MScefClaire S.DuvernoyMDgMarie-NoelleLanganMDhKristinWestBAiPoonamVelagapudiMDaSenaKillicMDjEdward L.O’LearyMD, MBA, MHCMa

doi : 10.1016/j.jacc.2021.06.033

Volume 78, Issue 9, 31 August 2021, Pages 898-909

Despite the increase in the number of female physicians across most specialties within cardiology, <10% of clinical cardiac electrophysiology (EP) fellows are women.

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Getting Into the Rhythm of Gender Parity in Electrophysiology?

Erin D.MichosMD, MHSaAnnabelle SantosVolgmanMDbKamala P.TamirisaMDc

doi : 10.1016/j.jacc.2021.06.036

Volume 78, Issue 9, 31 August 2021, Pages 910-913

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Cryoballoon Ablation as Initial Treatment for Atrial Fibrillation: JACC State-of-the-Art Review

Jason G.AndradeMDabcOussama M.WazniMDdMalteKunissMDeNathaniel M.HawkinsMDabMarc W.DeyellMD, MScabGian-BattistaChierchiaMDfStevenNissenMDdAtulVermaMDgGeorge A.WellsPhDhRicky D.TurgeonPharmDa

doi : 10.1016/j.jacc.2021.06.038

Volume 78, Issue 9, 31 August 2021, Pages 914-930

Atrial fibrillation (AF), the most common sustained arrhythmia observed in clinical practice, is a chronic and progressive disorder characterized by exacerbations and remissions. Guidelines recommend antiarrhythmic drugs as the initial therapy for the maintenance of sinus rhythm; however, antiarrhythmic drugs have modest efficacy to maintain sinus rhythm and can be associated with significant adverse effects. An initial treatment strategy of cryoballoon catheter ablation in patients with treatment-naïve AF has been shown to significantly improve arrhythmia outcomes (freedom from any, or symptomatic atrial tachyarrhythmia), produce clinically meaningful improvements in patient-reported outcomes (symptoms and quality of life), and significantly reduce subsequent health care resource use (hospitalization), and it does not increase the risk of serious or any adverse events compared with initial antiarrhythmic drug therapy. These findings are relevant to inform patients, providers, and health care systems regarding the initial choice of rhythm-control therapy in patients with treatment-naïve AF.

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Device Therapy in Chronic Heart Failure: JACC State-of-the-Art Review

MaratFudimMD, MHSabWilliam T.AbrahamMDcRalph Stephanvon BardelebenMDdJoAnnLindenfeldMDePiotr P.PonikowskiMD, PhDfgHusam M.SalahMDhMuhammad ShahzebKhanMD, MSiHorstSievertMDjkGregg W.StoneMDlmStefan D.AnkerMDnopJavedButlerMD, MBA, MPHi

doi : 10.1016/j.jacc.2021.06.040

Volume 78, Issue 9, 31 August 2021, Pages 931-956

The regulatory landscape for device-based heart failure (HF) therapies has seen a major shift in the last 7 years. In 2013, the U.S. Food and Drug Administration released guidance for early feasibility and first-in-human studies, thereby encouraging device innovation, and in 2016 the U.S. Congress authorized the Breakthrough Devices Program to expedite access for Americans to innovative devices indicated for diagnosis and treatment of serious illnesses, such as HF. Since December 2016, there has been an increase in the number of HF devices for which manufacturers are seeking approval through the breakthrough designation pathway. This has led to a rapid uptake in the development and evaluation of device-based HF therapies. This article reviews the current and future landscape of device therapies for chronic HF and associated comorbidities and the regulatory environment that is driving current and future innovation.

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The Ancient Heart: What the Heart Meant to Our Ancestors

Vincent MichaelFigueredoMD

doi : 10.1016/j.jacc.2021.06.041

Volume 78, Issue 9, 31 August 2021, Pages 957-959

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2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia: A Report of the American College of Cardiology Solution Set Oversight Committee

Salim S.ViraniMD, PhD, FACC(Chair)Pamela B.MorrisMD, FACC(Vice Chair)AnanditaAgarwalaMDChristie M.BallantyneMD, FACCKim K.BirtcherPharmD, MS, CDE, AACCPenny M.Kris-EthertonPhD, RDAmanda B.Ladden-StirlingMPPMichaelMillerMD, FACCCarl E.OrringerMD, FACCNeil J.StoneMD, FACC

doi : 10.1016/j.jacc.2021.06.011

Volume 78, Issue 9, 31 August 2021, Pages 960-993

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Innovation: Food, Nutrition, and the Promise of Heart Health

DiptiItchhaporiaMD, FACC(President, American College of Cardiology)

doi : 10.1016/j.jacc.2021.07.021

Volume 78, Issue 9, 31 August 2021, Pages 994-997

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Oxalic Cardiomyopathy: Could it Influence Treatment Plans in Patients With Primary Hyperoxaluria Type 1?

AlessandroDi ToroMDMarioUrtisBMELorenzoGiulianiBSCarloPellegriniMD, PhDAlexandraSmirnovaPhDRaffaeleGalatoMDAdeleValentiniMDHusseinJallousMDSergioScaccabarozziMDEloisaArbustiniMD

doi : 10.1016/j.jacc.2021.06.039

Volume 78, Issue 9, 31 August 2021, Pages 998-999

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