Journal of the American College of Cardiology




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doi : 10.1016/S0735-1097(21)05598-4

Volume 78, Issue 7, 17 August 2021, Page e37

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Contents

doi : 10.1016/S0735-1097(21)05600-X

Volume 78, Issue 7, 17 August 2021, Pages e39-e42

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Clinical Risk Prediction in Patients With Left Ventricular Myocardial Noncompaction

GuillemCasasMDabJavierLimeresMDabcGerardOristrellMDabLauraGutierrez-GarciaMDabcDanieleAndreiniMD, PhDdeMarBorreganPhDfJose M.Larra?aga-MoreiraMDgAngelaLopez-SainzMD, PhDbhiMartaCodina-SolàPhDcGiselaTeixido-TuraMD, PhDabcJosé AntonioSorolla-RomeroMDjPaulaFern?ndez-?lvarezMDcJosefaGonz?lez-CarrilloMDkAndreaGualaPhDaLuciaLa MuraMDlRafaelaSoler-Fern?ndezMDmAugustoSao AvilésPhDnopJuan JoséSantos-MateoMDqJosep RamonMarsalPhDrsAidaRiberaPhDrsJosé Luisde la PompaPhDbtEduardoVillacortaMDbuJuanJiménez-J?imezMD, PhDbvTom?sRipoll-VeraMD, PhDbwAntoniBayes-GenisMD, PhDbxyzJosé ManuelGarcia-PinillaMD, PhDbaaJuli?nPalomino-DozaMD, PhDbbbColomaTironMDbccddGianlucaPontoneMD, PhDdJanBogaertMDeeGiovanni D.AquaroMDffJuan RamonGimeno-BlanesMD, PhDbkEstherZorioMD, PhDbgghhPabloGarcia-PaviaMD, PhDbhiiiRobertoBarriales-VillaMD, PhDbgArturEvangelistaMD, PhDabcPier GiorgioMasciMD, PhDjjIgnacioFerreira-Gonz?lezMD, PhDarsJosé F.Rodr?guez-PalomaresMD, PhDabc

doi : 10.1016/j.jacc.2021.06.016

Volume 78, Issue 7, 17 August 2021, Pages 643-662

Left ventricular noncompaction (LVNC) is a heterogeneous entity with uncertain prognosis.

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Risk Prediction in a Debated Diagnosis: Is it Time for LVNC Guidelines??

John L.JefferiesMD, MPH

doi : 10.1016/j.jacc.2021.06.031

Volume 78, Issue 7, 17 August 2021, Pages 663-665

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Lignan Intake and Risk of Coronary Heart Disease

YangHuScDaYanpingLiPhDaLauraSampsonRDaMolinWangPhDbcJoAnn E.MansonMD, DrPHbdeEricRimmScDabdQiSunMD, ScDabdf

doi : 10.1016/j.jacc.2021.05.049

Volume 78, Issue 7, 17 August 2021, Pages 666-678

Evidence regarding lignan consumption in relation to coronary heart disease (CHD) risk remains limited and mixed.

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Plant Polyphenols Lignans and Cardiovascular Disease?

David J.A.JenkinsMD, PhDabcdeCyril W.C.KendallPhDacfJohn L.SievenpiperMD, PhDabcde

doi : 10.1016/j.jacc.2021.06.014

Volume 78, Issue 7, 17 August 2021, Pages 679-682

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Association of Preterm Birth With Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood

Adam J.LewandowskiDPhilabcBettyRamanMBBS, DPhilbcMarianeBertagnolliPhDadAfifahMohamedDPhilaeWilbyWilliamsonBMBS, DPhilaJoana LealPeladoBScbcAngusMcCanceBMBChaWinokLapidairePhDaStefanNeubauerMDbcPaulLeesonMB, PhDac

doi : 10.1016/j.jacc.2021.05.053

Volume 78, Issue 7, 17 August 2021, Pages 683-692

Preterm birth affects about 10% of live births worldwide and is associated with cardiac alterations. Animal models of preterm birth suggest that left ventricular functional impairment may be due to an up-regulation of myocardial fibrosis.

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Is Myocardial Fibrosis the Missing Link Between Prematurity, Cardiac Remodeling, and Long-Term Cardiovascular Outcomes??

TalGevaMDEmily M.BucholzMD, PhD, MPH

doi : 10.1016/j.jacc.2021.05.052

Volume 78, Issue 7, 17 August 2021, Pages 693-695

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Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors

JonasGhouseMD, PhDabGustavAhlbergMSc, PhDabLauraAndreasenMDabKarinaBanasikMSc, PhDcS?renBrunakMSc, PhD, DMSccMichaelSchwinnMSc, PhDdIna HolstLarsenMScdOscarPetersenMScdErikS?rensenMSc, PhDdHenrikUllumMD, PhDeEva RyeRasmussenMD, PhDfNiclasErikssonMSc, PhDgP?rHallbergMD, PhDhMiaWadeliusMD, PhDhHenningBundgaardMD, DMSciMorten S.OlesenMSc, PhDab

doi : 10.1016/j.jacc.2021.05.054

Volume 78, Issue 7, 17 August 2021, Pages 696-709

Angioedema is a rare but potentially life-threatening adverse reaction associated with angiotensin-converting enzyme (ACE) inhibitors. Identification of potential genetic factors related to this adverse event may help identify at-risk patients.

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Novel Pharmacogenomic Locus Implicated in Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema?

Stuart A.ScottPhDabPaolaNicolettiMD, PhDcd

doi : 10.1016/j.jacc.2021.05.050

Volume 78, Issue 7, 17 August 2021, Pages 710-712

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Coronary Computed Tomographic Angiography for Complete Assessment of Coronary Artery Disease: JACC State-of-the-Art Review

Patrick W.SerruysMD, PhDab?HironoriHaraMDac?ScotGargMD, PhDdHideyukiKawashimaMDacBjarne L.N?rgaardMD, PhDeMarc R.DweckMD, PhDfJeroen J.BaxMD, PhDgJuhaniKnuutiMD, PhDhKoenNiemanMD, PhDiJonathon A.LeipsicMDjSaimaMushtaqMDkDanieleAndreiniMD, PhDklYoshinobuOnumaMD, PhDa

doi : 10.1016/j.jacc.2021.06.019

Volume 78, Issue 7, 17 August 2021, Pages 713-736

Coronary computed tomography angiography (CTA) has shown great technological improvements over the last 2 decades. High accuracy of CTA in detecting significant coronary stenosis has promoted CTA as a substitute for conventional invasive coronary angiography in patients with suspected coronary artery disease. In patients with coronary stenosis, CTA-derived physiological assessment is surrogate for intracoronary pressure and velocity wires, and renders possible decision-making about revascularization solely based on computed tomography. Computed tomography coronary anatomy with functionality assessment could potentially become a first line in diagnosis. Noninvasive imaging assessment of plaque burden and morphology is becoming a valuable substitute for intravascular imaging. Recently, wall shear stress and perivascular inflammation have been introduced. These assessments could support risk management for both primary and secondary cardiovascular prevention. Anatomy, functionality, and plaque composition by CTA tend to replace invasive assessment. Complete CTA assessment could provide a 1-stop-shop for diagnosis, risk management, and decision-making on treatment.

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Increasing Participation of Women in Cardiovascular Trials: JACC Council Perspectives

LeslieChoMDaAmanda R.VestMBBS, MPHbMichelle L.O’DonoghueMD, MPHcModele O.OgunniyiMDdAmy A.SarmaMDeKara J.DenbyMDaEmily S.LauMDeJeanne E.PooleMDfKathryn J.LindleyMDgRoxanaMehranMDhCardiovascular Disease in Women Committee Leadership Council

doi : 10.1016/j.jacc.2021.06.022

Volume 78, Issue 7, 17 August 2021, Pages 737-751

Although some progress has been made in the last 3 decades to increase the number of women in clinical cardiology trials, review of recent cardiovascular literature demonstrates that women and underrepresented minority women are still underrepresented in most clinical cardiology trials. This is especially notable in trials of patients with coronary artery disease, heart failure with reduced ejection fraction, and arrhythmia studies, especially those involving devices and procedures. Despite the call from National Institutes of Health, Food and Drug Administration, Institute of Medicine, and various professional societies, the gap remains. This paper seeks to identify the barriers for low enrollment and retention from patient, clinician, research team, study design, and system perspectives, and offers recommendations to improve recruitment and retention in the current era.

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Clinician Well-Being: Addressing Global Needs for Improvements in the Health Care Field A Joint Opinion From the American College of Cardiology, American Heart Association, European Society of Cardiology, and the World Heart Federation

Laxmi S.MehtaMD, FACC, FAHAaMitchell S.V.ElkindMD, MS, FAHAbcStephanAchenbachMD, FACC, FESCdeFausto J.PintoMD, FACC, FESCfgAthenaPoppasMD, MACC, FAHAhi

doi : 10.1016/j.jacc.2021.04.043

Volume 78, Issue 7, 17 August 2021, Pages 752-756

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Rivaroxaban in Patients With Recent Peripheral Artery Revascularization and Renal Impairment: The VOYAGER PAD Trial

JudithHsiaMDMichaelSzarekPhDSoniaAnandMDManesh R.PatelMDSebastianDebusMD, PhDScott D.BerkowitzMDEvaMuehlhoferMDLloyd P.HaskellMDRupert M.BauersachsMDMarc P.BonacaMD, MPH

doi : 10.1016/j.jacc.2021.06.021

Volume 78, Issue 7, 17 August 2021, Pages 757-759

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Pneumonia in Chronic Heart Failure: What About a Full Picture of the Puzzle?

NathanMewtonMD, PhDGuillaumeBaudryMDLaurentSebbagMD, PhD

doi : 10.1016/j.jacc.2021.04.107

Volume 78, Issue 7, 17 August 2021, Page 759

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Infection and Adverse Outcomes in People With Chronic Heart Failure: Highlighting a Neglected Problem

MichaelDrozdMBChBRichard M.CubbonMBChB, PhD

doi : 10.1016/j.jacc.2021.04.106

Volume 78, Issue 7, 17 August 2021, Page 760

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Reply: Pneumonia and the Bigger Picture of Infection in Heart Failure

LiShenMBChB, PhDPardeep S.JhundMBChB, MSc, PhDJohn J.V.McMurrayMD

doi : 10.1016/j.jacc.2021.06.006

Volume 78, Issue 7, 17 August 2021, Pages 760-761

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Correction

doi : 10.1016/j.jacc.2021.06.032

Volume 78, Issue 7, 17 August 2021, Page 762

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