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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Medical treatment for heavy bleeding in copper IUD users

Medical treatment for heavy bleeding in copper IUD users
Timing Medication class Medication Oral dose Frequency Length of time
Prophylaxis of postinsertion bleeding* NSAID Ibuprofen 400 mg 3 times daily 10 days
Antifibrinolytic Tranexamic acid 650 mg (US available prescription) 2 times daily 5 days
Tranexamic acid 500 mg (preparation is not available in US) 2 times daily 5 days
Treatment of heavy bleeding >3 months postinsertion NSAID Ibuprofen 400 mg 4 times daily 7 days
Indomethacin 25 mg 2 times daily 7 days
Indomethacin 25 mg 4 times daily 3 days
Mefenamic acid 100 mg (preparation is not available in US) 3 times daily 3 days
Mefenamic acid 500 mg (US available preparation) 3 times daily 5 days
Diclofenac 50 mg 3 times daily 1 day, then
25 mg 3 times daily 4 days
Antifibrinolytic Tranexamic acid 1300 mg (US available preparation) 3 times daily 5 days
Tranexamic acid 1500 mg (preparation is not available in US) 3 times daily 5 days
Antidiuretic Desmopressin 300 mcg intranasally Intranasal daily 5 days
Treatment is initiated on the first day of menses, or alternatively several days before expected menstruation, to reduce bleeding and cramping. Aspirin is not recommended.
NSAIDs are generally avoided in patients with renal impairment, reduced cardiac output, difficult to control hypertension and some other comorbidities; refer to UpToDate clinical reviews of NSAID safety and individual Lexicomp drug monograph for detail.
NSAID: nonsteroidal anti-inflammatory drug; US: United States.
* UpToDate contributors generally do not use prophylactic medication as the abnormal bleeding typically resolves quickly and most women do well with advance education.
¶ Dose adjustment needed in setting of renal impairment.
Reproduced from: Friedlander E, Kaneshiro B. Therapeutic options for unscheduled bleeding associated with long-acting reversible contraception. Obstet Gynecol Clin North Am 2015; 42:593. Table used with the permission of Elsevier Inc. All rights reserved.
Graphic 113193 Version 1.0

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