NF-kappa-B-dependent signaling pathways

TLR: toll-like receptor; MyD88: myeloid differentiation primary response protein 88; IRAK: interleukin-1 receptor-associated kinase; NLRs: nucleotide oligomerization domain (NOD)-like receptors; RLRs: retinoic acid-inducible gene-I (RIG-I)-like receptors; TCR: T cell receptor; BCR: B cell receptor; CD40: cluster of differentiation 40, a costimulatory protein found on antigen-presenting cells, which is required for their activation; EDAR: ectodysplasin A receptor; NF-kappa-B: nuclear factor (NF) for the kappa light chain enhancer in B cells.